Annotation Detail

Information
Associated Genes
IL1B
Associated Variants
IL1B MUTATION
IL1B MUTATION
Associated Disease
Metabolic Diseases
Source Database
DisGeNET
Description
IL-1β-secreting nucleotide-binding oligomerization domain protein 3 (NLRP3) inflammasomes play a pivotal role in triggering innate immune responses in metabolic disease.
Pubmed
25651569
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs