Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
IL10 c.378+19T>C
(
ENST00000664374.2,
ENST00000659065.2,
ENST00000471071.2,
ENST00000656872.2,
ENST00000659997.3,
ENST00000659642.2,
ENST00000423557.1 )
IL19 c.-149+2474T>C ( ENST00000656872.2, ENST00000659642.2, ENST00000659997.3, ENST00000664374.2, ENST00000659065.2 )
TNF c.-488G>A
IL10 c.378+19T>C ( ENST00000423557.1, ENST00000471071.2, ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
IL19 c.-149+2474T>C ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
TNF c.-488G>A - Associated Disease
- Cervical Intraepithelial Neoplasia
- Source Database
- DisGeNET
- Description
- When compared to controls, the CIN patients showed increased frequencies of CC (rs1554286) and AG+GG (rs1800896) genotypes in IL-10 and GA+AA (rs1800629) genotype in TNF-α (OR = 2.24 (1.13-4.44), p = 0.018; OR = 2.61 (1.30-5.26), p = 0.005, and OR = 2.11 (1.08-4.09), p = 0.025, respectively).
- Pubmed
- 23363891
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00609127331760558
- Year of publication
- 2013
Drugs