Annotation Detail

Information
Associated Genes
TLR2
Associated Variants
TLR2 MUTATION
TLR2 MUTATION
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
Increased expression of TLR2 in CD4(+) T cells from SLE patients enhances immune reactivity and promotes IL-17 expression through histone modifications.
Pubmed
26079624
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Drugs