Annotation Detail

Information
Associated Genes
SLC6A3
Associated Variants
COMT p.Val158Met (p.V158M) ( ENST00000361682.11, ENST00000403184.5, ENST00000403710.5, ENST00000406520.7, ENST00000407537.5, ENST00000428707.2, ENST00000449653.5, ENST00000676678.1, ENST00000678255.1, ENST00000678769.1, ENST00000678868.1 )
MEPE p.Val189Met (p.V189M) ( ENST00000361056.4, ENST00000395102.8, ENST00000424957.8, ENST00000497649.6, ENST00000560249.6 )
COMT p.Val158Met (p.V158M) ( ENST00000361682.11, ENST00000403184.5, ENST00000403710.5, ENST00000406520.7, ENST00000407537.5, ENST00000428707.2, ENST00000449653.5, ENST00000676678.1, ENST00000678255.1, ENST00000678769.1, ENST00000678868.1 )
MEPE p.Val189Met (p.V189M) ( ENST00000361056.4, ENST00000395102.8, ENST00000424957.8, ENST00000497649.6, ENST00000560249.6 )
Associated Disease
attention deficit hyperactivity disorder
Source Database
DisGeNET
Description
We genotyped a sample of 45 adults with ADHD at four candidate polymorphisms for the disorder (DRD4 48 base pair (bp) repeat, DRD4 120 bp duplicated repeat, SLC6A3 (DAT1) 40 bp variable number of tandem repeats (VNTR), and COMT Val158Met).
Pubmed
17886261
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.340018448294739
Year of publication
2008
Drugs