Annotation Detail

Information
Associated Genes
IL6
Associated Variants
IL6 MUTATION
IL6 MUTATION
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
In addition, blocking the autocrine-loop of IL-6 in SLE B cells with an anti-IL-6 receptor monoclonal antibody restores DNA methylation and control of HRES-1/p28 expression became effective.
Pubmed
24117194
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN
DisGENET score for the Gene Disease association
0.150227193846014
Drugs