Annotation Detail
Information
- Associated Genes
- HTR2A
- Associated Variants
-
TPH2 c.608+9108T>C
(
ENST00000333850.4 )
HTR2A p.Val241Leu (p.V241L) ( ENST00000543956.5, ENST00000542664.4 )
HTR2A p.Val241Met (p.V241M) ( ENST00000542664.4, ENST00000543956.5 )
COMT p.Val158Met (p.V158M) ( ENST00000361682.11, ENST00000403184.5, ENST00000403710.5, ENST00000406520.7, ENST00000407537.5, ENST00000428707.2, ENST00000449653.5, ENST00000676678.1, ENST00000678255.1, ENST00000678769.1, ENST00000678868.1 )
TPH2 c.608+9108T>C ( ENST00000333850.4 )
HTR2A p.Val241Leu (p.V241L) ( ENST00000542664.4, ENST00000543956.5 )
HTR2A p.Val241Met (p.V241M) ( ENST00000542664.4, ENST00000543956.5 )
COMT p.Val158Met (p.V158M) ( ENST00000361682.11, ENST00000403184.5, ENST00000403710.5, ENST00000406520.7, ENST00000407537.5, ENST00000428707.2, ENST00000449653.5, ENST00000676678.1, ENST00000678255.1, ENST00000678769.1, ENST00000678868.1 ) - Associated Disease
- panic disorder
- Source Database
- DisGeNET
- Description
- Nine gene-candidates, including 5-HTTLPR, MAO-A VNTR, TPH2 rs1386494, 5-HTR1A -1019C-G, 5-HTR2A 102T-C, CCKR1 246G-A, CCKR2 -215C-A, DRD1 -94G-A and COMT Val158Met, were selected for genotyping based on previous positive findings from genetic association studies in PD.
- Pubmed
- 18832011
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0197268372266672
- Year of publication
- 2008
Drugs