Annotation Detail

Information
Associated Genes
TSC2
Associated Variants
TSC2 p.His1746_Arg1751del (p.H1746_R1751del) ( ENST00000644329.1, ENST00000642797.1, ENST00000350773.9, ENST00000644043.1, ENST00000382538.10, ENST00000439673.6, ENST00000642365.2, ENST00000646388.1, ENST00000642561.1, ENST00000643088.1, ENST00000401874.7, ENST00000568454.6, ENST00000643946.1, ENST00000642206.2, ENST00000644335.1, ENST00000642936.1, ENST00000219476.9, ENST00000645186.2 )
TSC2 p.His1746_Arg1751del (p.H1746_R1751del) ( ENST00000219476.9, ENST00000350773.9, ENST00000382538.10, ENST00000401874.7, ENST00000439673.6, ENST00000568454.6, ENST00000642206.2, ENST00000642365.2, ENST00000642561.1, ENST00000642797.1, ENST00000642936.1, ENST00000643088.1, ENST00000643946.1, ENST00000644043.1, ENST00000644329.1, ENST00000644335.1, ENST00000645186.2, ENST00000646388.1 )
TSC2 p.Glu366Lys (p.E366K) ( ENST00000401874.7, ENST00000350773.9, ENST00000568454.6, ENST00000382538.10, ENST00000219476.9, ENST00000439673.6, ENST00000642206.2, ENST00000642365.2, ENST00000642561.1, ENST00000642797.1, ENST00000642936.1, ENST00000643088.1, ENST00000643946.1, ENST00000644043.1, ENST00000644329.1, ENST00000644335.1, ENST00000645186.2, ENST00000646388.1 )
TSC2 p.Glu366Ter (p.E366*) ( ENST00000642936.1, ENST00000642561.1, ENST00000401874.7, ENST00000643088.1, ENST00000644329.1, ENST00000642206.2, ENST00000644335.1, ENST00000439673.6, ENST00000642365.2, ENST00000646388.1, ENST00000350773.9, ENST00000382538.10, ENST00000644043.1, ENST00000219476.9, ENST00000645186.2, ENST00000568454.6, ENST00000643946.1, ENST00000642797.1 )
TSC2 p.Arg505Ter (p.R505*) ( ENST00000350773.9, ENST00000642797.1, ENST00000646388.1, ENST00000439673.6, ENST00000643946.1, ENST00000644335.1, ENST00000642206.2, ENST00000568454.6, ENST00000644329.1, ENST00000642561.1, ENST00000645186.2, ENST00000642936.1, ENST00000644043.1, ENST00000382538.10, ENST00000642365.2, ENST00000401874.7, ENST00000643088.1, ENST00000219476.9 )
TSC2 p.Arg611Gln (p.R611Q) ( ENST00000350773.9, ENST00000644043.1, ENST00000646388.1, ENST00000642561.1, ENST00000642797.1, ENST00000382538.10, ENST00000439673.6, ENST00000642365.2, ENST00000644329.1, ENST00000643088.1, ENST00000401874.7, ENST00000568454.6, ENST00000643946.1, ENST00000644335.1, ENST00000642206.2, ENST00000642936.1, ENST00000219476.9, ENST00000645186.2 )
TSC2 p.Pro1675Leu (p.P1675L) ( ENST00000439673.6, ENST00000401874.7, ENST00000219476.9, ENST00000382538.10, ENST00000568454.6, ENST00000350773.9, ENST00000642206.2, ENST00000642365.2, ENST00000642561.1, ENST00000642797.1, ENST00000642936.1, ENST00000643088.1, ENST00000643946.1, ENST00000644043.1, ENST00000644329.1, ENST00000644335.1, ENST00000645186.2, ENST00000646388.1 )
TSC2 p.Glu366Lys (p.E366K) ( ENST00000219476.9, ENST00000350773.9, ENST00000382538.10, ENST00000401874.7, ENST00000439673.6, ENST00000568454.6, ENST00000642206.2, ENST00000642365.2, ENST00000642561.1, ENST00000642797.1, ENST00000642936.1, ENST00000643088.1, ENST00000643946.1, ENST00000644043.1, ENST00000644329.1, ENST00000644335.1, ENST00000645186.2, ENST00000646388.1 )
TSC2 p.Glu366Ter (p.E366*) ( ENST00000219476.9, ENST00000350773.9, ENST00000382538.10, ENST00000401874.7, ENST00000439673.6, ENST00000568454.6, ENST00000642206.2, ENST00000642365.2, ENST00000642561.1, ENST00000642797.1, ENST00000642936.1, ENST00000643088.1, ENST00000643946.1, ENST00000644043.1, ENST00000644329.1, ENST00000644335.1, ENST00000645186.2, ENST00000646388.1 )
TSC2 p.Arg505Ter (p.R505*) ( ENST00000219476.9, ENST00000350773.9, ENST00000382538.10, ENST00000401874.7, ENST00000439673.6, ENST00000568454.6, ENST00000642206.2, ENST00000642365.2, ENST00000642561.1, ENST00000642797.1, ENST00000642936.1, ENST00000643088.1, ENST00000643946.1, ENST00000644043.1, ENST00000644329.1, ENST00000644335.1, ENST00000645186.2, ENST00000646388.1 )
TSC2 p.Arg611Gln (p.R611Q) ( ENST00000219476.9, ENST00000350773.9, ENST00000382538.10, ENST00000401874.7, ENST00000439673.6, ENST00000568454.6, ENST00000642206.2, ENST00000642365.2, ENST00000642561.1, ENST00000642797.1, ENST00000642936.1, ENST00000643088.1, ENST00000643946.1, ENST00000644043.1, ENST00000644329.1, ENST00000644335.1, ENST00000645186.2, ENST00000646388.1 )
TSC2 p.Pro1675Leu (p.P1675L) ( ENST00000219476.9, ENST00000350773.9, ENST00000382538.10, ENST00000401874.7, ENST00000439673.6, ENST00000568454.6, ENST00000642206.2, ENST00000642365.2, ENST00000642561.1, ENST00000642797.1, ENST00000642936.1, ENST00000643088.1, ENST00000643946.1, ENST00000644043.1, ENST00000644329.1, ENST00000644335.1, ENST00000645186.2, ENST00000646388.1 )
Associated Disease
lymphangioleiomyomatosis
Source Database
DisGeNET
Description
NA
Original source reporting the Gene Disease association
CLINVAR
DisGENET score for the Gene Disease association
0.576859190633971
Year of publication
NA
Drugs