Annotation Detail

Information
Associated Genes
MGMT
Associated Variants
MGMT MUTATION
MGMT MUTATION
MGMT p.Leu84Phe (p.L84F) ( ENST00000306010.8, ENST00000651593.1 )
MGMT p.Ile143Val (p.I143V) ( ENST00000651593.1, ENST00000306010.8 )
MGMT p.Leu84Phe (p.L84F) ( ENST00000306010.8, ENST00000651593.1 )
MGMT p.Ile143Val (p.I143V) ( ENST00000306010.8, ENST00000651593.1 )
Associated Disease
colorectal carcinoma
Source Database
DisGeNET
Description
O6-methylguanine-DNA methyltransferase Leu84Phe and Ile143Val polymorphisms and risk of colorectal cancer in the Nurses' Health Study and Physicians' Health Study (United States).
Pubmed
16633920
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0143864192202561
Year of publication
2006
Drugs