Annotation Detail

Information
Associated Genes
PON1
Associated Variants
PON1 MUTATION
PON1 MUTATION
Associated Disease
male infertility
Source Database
DisGeNET
Description
We speculate that the low activity of PON1 can be a risk factor for male infertility probably due to a decrease in antioxidant activity of PON1 and increase in lipid peroxidation.
Pubmed
25264968
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree,CTD_human
DisGENET score for the Gene Disease association
0.121085767488321
Drugs