Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
-
MGMT c.-12-9206C>T
(
ENST00000651593.1,
ENST00000306010.8 )
MGMT c.-12-9206C>T ( ENST00000306010.8, ENST00000651593.1 ) - Associated Disease
- gastroesophageal reflux disease
- Source Database
- DisGeNET
- Description
- Homozygous carriers of MGMT rs12268840 with frequent acid reflux had significantly higher risks of EAC (OR 15.5, 95% CI 5.8-42) than expected under an additive model, consistent with biological interaction (S = 3.3, 95% CI 1.1-10).
- Pubmed
- 18386788
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2008
Drugs