Annotation Detail

Information
Associated Genes
CCR5
Associated Variants
CCR5 MUTATION
CCR5 MUTATION
Associated Disease
HIV Infections
Source Database
DisGeNET
Description
The entry inhibitor drug maraviroc makes the cell coreceptor CCR5 unavailable for use by HIV-1 and is now used in combination antiretroviral therapy.
Pubmed
26339063
Section of the abstract supporting the evidence
IMPORTANCE
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.184519152182205
Drugs