Annotation Detail
Information
- Associated Genes
- CCR5
- Associated Variants
-
CCR5 MUTATION
CCR5 MUTATION - Associated Disease
- HIV Infections
- Source Database
- DisGeNET
- Description
- HIV-1 Nef, a key factor for viral pathogenesis, downregulates functionally important molecules from the surface of infected cells, including the viral entry receptor CD4 and coreceptors CCR5 and CXCR4.
- Pubmed
- 26178998
- Section of the abstract supporting the evidence
- IMPORTANCE
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 11
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.184519152182205
Drugs