Annotation Detail
Information
- Associated Genes
- CCR5
- Associated Variants
-
CCR5 MUTATION
CCR5 MUTATION - Associated Disease
- HIV Infections
- Source Database
- DisGeNET
- Description
- When pDC were depleted prior to HIV-1 infection, the induction of IFN-I and interferon-stimulated genes (ISGs) were abolished during acute HIV-1 infection with either a highly pathogenic CCR5/CXCR4-dual tropic HIV-1 or a standard CCR5-tropic HIV-1 isolate.
- Pubmed
- 25077616
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.184519152182205
Drugs