Annotation Detail

Information
Associated Genes
CCR5
Associated Variants
CCR5 MUTATION
CCR5 MUTATION
Associated Disease
HIV Infections
Source Database
DisGeNET
Description
Enhanced HIV-1 replication was associated with increased CD4, CCR5, and CD38 transcription (P<0.05) and increased number of CD4(+)/CCR5(+)/CD38(+) T cells in HIV-1/HSV-2 co-infected tissues compared with tissues infected with HIV-1 alone.
Pubmed
24496317
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.184519152182205
Drugs