Annotation Detail

Information
Associated Genes
CCR5
Associated Variants
CCR5 MUTATION
CCR5 MUTATION
Associated Disease
Graft-vs-Host Disease
Source Database
DisGeNET
Description
Several recent clinical trials were all based on previously reported findings from the mouse model of GvHD such as the trials on CCR5-blockade, donor statin treatment, vorinostat treatment or adoptive transfer of regulatory T cells for GvHD prevention.
Pubmed
25532439
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0130068037731162
Drugs