Annotation Detail

Information
Associated Genes
MGMT
Associated Variants
MGMT MUTATION
MGMT MUTATION
Associated Disease
Glioma
Source Database
DisGeNET
Description
The O6-methylguanine-DNAmethyltransferase (MGMT) promoter methylation and 1p19q codeletion status can predict sensitivity to chemotherapy and radiation in low- and intermediate-grade gliomas.
Pubmed
25727224
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN
DisGENET score for the Gene Disease association
0.176010290518581
Drugs