Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
-
MGMT MUTATION
MGMT MUTATION - Associated Disease
- Glioma
- Source Database
- DisGeNET
- Description
- MGMT (O(6)-methylguanine-DNA methyltransferase) controls DNA repair pathways, and its epigenetic silencing is used for predicting the response to the alkylating drug temozolomide in patients with glioma.
- Pubmed
- 24709436
- Section of the abstract supporting the evidence
- BACKGROUND
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.176010290518581
Drugs