Annotation Detail
Information
- Associated Genes
- TLR4
- Associated Variants
-
TLR4 MUTATION
TLR4 MUTATION - Associated Disease
- diabetic retinopathy
- Source Database
- DisGeNET
- Description
- Collectively, our novel data suggest that hyperglycemia induces TLR-2 and TLR-4 activation and downstream signaling mediating increased inflammation possibly via reactive oxygen species (ROS) and could contribute to DR.
- Pubmed
- 25610879
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00135720936040152
Drugs