Annotation Detail

Information
Associated Genes
TYMS
Associated Variants
TYMS MUTATION
TYMS MUTATION
Associated Disease
colorectal carcinoma
Source Database
DisGeNET
Description
Arsenic trioxide (ATO) has been shown to suppress thymidylate synthase (TYMS) in lung adenocarcinoma and colorectal cancer, and induce apoptosis in acute promyelocytic leukemia.
Pubmed
25335113
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0325730246496364
Drugs