Annotation Detail

Information
Associated Genes
CDKN2A
Associated Variants
CDKN2A MUTATION
CDKN2A MUTATION
Associated Disease
colorectal carcinoma
Source Database
DisGeNET
Description
An adenoviral construct of the human p14ARF gene (a tumor suppressor) and a 22 amino acid sequence of the ARF gene product, which has cell membrane penetrating properties, were assayed for proapoptotic properties in a human colorectal cancer cell line (Clone A) cells in vitro.
Pubmed
25935465
Section of the abstract supporting the evidence
MATERIALS AND METHODS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0236154428709864
Drugs