Annotation Detail

Information
Associated Genes
PTPRC
Associated Variants
PTPRC MUTATION
PTPRC MUTATION
Associated Disease
cholestasis
Source Database
DisGeNET
Description
The in vivo experiments using PXR siRNA revealed that Tan IIA could protect against LCA-induced hepatotoxicity and cholestasis in a dose-dependent manner.
Pubmed
25660334
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs