Annotation Detail

Information
Associated Genes
GATA4
Associated Variants
GATA4 p.Gly88Val (p.G88V) ( ENST00000335135.8, ENST00000528712.5, ENST00000532059.6, ENST00000622443.3 )
GATA4 p.Gly88Val (p.G88V) ( ENST00000335135.8, ENST00000528712.5, ENST00000532059.6, ENST00000622443.3 )
Associated Disease
Atrial septal defect 2 Testicular anomalies with or without congenital heart disease Ventricular septal defect 1 Atrioventricular septal defect 4 tetralogy of Fallot
Source Database
ClinVar
Description
NM_001308093.3(GATA4):c.263G>T (p.Gly88Val) AND multiple conditions
ClinVar Allele ID
457788
ClinVar RefSeq Alternation Syntax
NM_001374273.1:c.-3+4271G>T
ClinVar RefSeq Alternation Syntax
NM_001308094.2:c.-6+7797G>T
ClinVar RefSeq Alternation Syntax
NM_001308093.3:c.263G>T
ClinVar RefSeq Alternation Syntax
NM_001374274.1:c.-3+561G>T
ClinVar RefSeq Alternation Syntax
NM_002052.5:c.263G>T
Clinical Significance Description
Uncertain significance
Clinical Significance Last Update
2018-10-31
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000765985
ClinVar Disease
Tetralogy of Fallot
ClinVar Disease
Ventricular septal defect 1
ClinVar Disease
Atrioventricular septal defect 4
ClinVar Disease
Atrial septal defect 2
ClinVar Disease
Testicular anomalies with or without congenital heart disease
Observed Origin Sample
unknown
Drugs