Annotation Detail
Information
- Associated Genes
- CCNE1
- Associated Variants
-
CCNE1 AMPLIFICATION
(
ENST00000262643.8 )
CCNE1 AMPLIFICATION ( ENST00000262643.8 ) - Associated Disease
- ovarian carcinoma
- Source Database
- CIViC Evidence
- Description
- In a retrospective study of 88 ovarian carcinomas, 18 had amplification of CCNE1. Those with amplification had worse overall and disease-free survival.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/466
- Gene URL
- https://civic.genome.wustl.edu/links/genes/11
- Variant URL
- https://civic.genome.wustl.edu/links/variants/187
- Rating
- 4
- Evidence Type
- Prognostic
- Disease
- Ovarian Carcinoma
- Evidence Direction
- Supports
- Evidence Level
- B
- Clinical Significance
- Poor Outcome
- Pubmed
- 20336784
Drugs