chr17:7661779:> Detail (hg38) (TP53)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr17:7,565,097-7,590,864 |
| hg38 | chr17:7,661,779-7,687,546 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
| Disease | Drug | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| ovarian cancer | Carboplatin,Cisplatin | B |
Predictive
|
Supports
|
Resistance | Somatic | 4 | 11595686 | Detail |
| ovarian cancer | B |
Prognostic
|
Supports
|
Poor Outcome | Somatic | 4 | 11595686 | Detail |
DisGeNET
[No Data.]
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| In a group of patients with invasive ovarian carcinoma who had undergone surgery, a subset of 74 pat... | CIViC Evidence | Detail |
| In a study of invasive ovarian carcinoma patients who had undergone surgery, the p53 alteration vari... | CIViC Evidence | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- Genome
- hg38
- Position
- chr17:7,661,779-7,687,546
- Variant Type
- snv
- Variant (CIViC) (CIViC Variant)
- ALTERATION
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/1307
- Summary (CIViC Variant)
- P53 ALTERATION is a bucket type variant used in studies which is constructed by combining all cases of p53 mutation together with p53 overexpression. This includes cases which have p53 mutation or overexpression alone or as well as cases where both occur in combination.
- Variant (CIViC) (CIViC Variant)
- L3 Domain Mutation
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/1318
- Variant (CIViC) (CIViC Variant)
- V135A
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/2624
- Variant (CIViC) (CIViC Variant)
- K132
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/2722
- Variant (CIViC) (CIViC Variant)
- R273
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/2725
- Variant (CIViC) (CIViC Variant)
- E204
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/2730
- Variant (CIViC) (CIViC Variant)
- T170
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/2733
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