chrX:107642390:> Detail (hg38) (PRPS1)

Information

Genome

Assembly Position
hg19 chrX:106,885,620-106,885,622 
hg38 chrX:107,642,390-107,642,392

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
Disease Drug EL ET ED CS VO TR Pubmed Links
childhood B-cell acute lymphoblastic leukemia Mercaptopurine,Thioguanine D Predictive Supports Resistance Somatic 4 25962120 Detail
childhood B-cell acute lymphoblastic leukemia Cytarabine D Predictive Supports Sensitivity/Response Somatic 2 25962120 Detail
childhood B-cell acute lymphoblastic leukemia Daunorubicin,Methotrexate,Asparaginase D Predictive Does Not Support Resistance Somatic 3 25962120 Detail
DisGeNET
[No Data.]
Annotation

Annotations

DescrptionSourceLinks
Lentiviral-mediated overexpression of PRPS1 N144S in Reh cells resulted in significant resistance ag... CIViC Evidence Detail
Lentiviral-mediated overexpression of PRPS1 N144S in Reh cells resulted in sensitivity to cytarabine... CIViC Evidence Detail
Lentiviral-mediated overexpression of PRPS1 N144S in Reh cells resulted no difference in response to... CIViC Evidence Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
Genome
hg38
Position
chrX:107,642,390-107,642,392
Variant Type
snv
Variant (CIViC) (CIViC Variant)
N144S
Variant URL (CIViC Variant)
https://civic.genome.wustl.edu/links/variants/2923
Genome browser