chr17:76210267:> Detail (hg19) (BIRC5)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr17:76,210,267-76,221,717 |
hg38 | chr17:78,214,186-78,225,636 |
HGVS
Type | Transcript | Protein |
---|---|---|
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
Clinical Significance | |
Review star | [No Data.] |
Show details |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
Disease | Drug | EL | ET | ED | CS | VO | TR | Pubmed | Links |
---|---|---|---|---|---|---|---|---|---|
lung non-small cell carcinoma | Taxane Compound,Platinum Compound | B |
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Sensitivity/Response |
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3 | 24961465 | Detail |
DisGeNET
[No Data.]
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
Patients with nuclear survivin (BIRC5) expression had significantly better responses to taxane-plati... | CIViC Evidence | Detail |
Impossible to determine whether survivin acts as a prognostic or predictive marker | MMMP | Detail |
TAT-Surv-T34A is a cell permeable survivin dominant-negative mutant | MMMP | Detail |
Dominant negative experiments | MMMP | Detail |
Uveal melanoma. Results based on both expression levels, forced expression and antisense oligo | MMMP | Detail |
Uveal melanoma. The combination of cisplatin and actinomycin-D significantly decreased survivin expr... | MMMP | Detail |
Uveal melanoma | MMMP | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- Genome
- hg19
- Position
- chr17:76,210,267-76,221,717
- Variant Type
- snv
- Variant (CIViC) (CIViC Variant)
- NUCLEAR EXPRESSION
- Transcript 1 (CIViC Variant)
- ENST00000301633.4
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/368
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