TOP3A DNA topoisomerase III alpha

Information
Symbol
TOP3A
Type
protein-coding
Description
DNA topoisomerase III alpha
Entrez Gene ID
7156
Genome
hg19
Position
chr17:18,174,742-18,218,308
Genome
hg38
Position
chr17:18,271,428-18,314,994
MIM
601243 OMIM
HGNC
HGNC:11992 HGNC
Ensembl
ENSG00000177302 Ensembl
Links
NCBI Gene Cards OncoKB
Clinical Significance
MGeND ClinVar
Pathogenic 14 26
Likely pathogenic 0 16
Benign 0 64
Likely benign 0 328
Conflicting classifications of pathogenicity 0 16
not provided 2 0
Uncertain significance 0 270
Ranking
ClinVar
0
0
114
562
10
Frequency
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
Disease area statistics
Locus Zoom
Variants
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Variant name Gene AA change CDS Japanese
frequency		 TogoVar MGeND Genome ClinVar CIViC evidence DisGeNET entry COSMIC
occurrence		 Prediction
Entry Origin Type Annotation Entry Origin Annotation
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Name MGeND Type Genome Size Chromosome Start Stop Ref Alt ClinVar Origin Entry CIViC evidence DisGeNET entry
Entry Origin Type Annotation
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Name MGeND Type Genome Gene symbol Chromosome Genomic start Genomic stop Strand Ref Alt ClinVar Origin Entry CIViC evidence DisGeNET entry
Entry Origin Type Annotation
TypeID
SYNONYM MGRISCE2
SYNONYM PEOB5
SYNONYM TOP3
SYNONYM ZGRF7
MIM 601243 OMIM
HGNC HGNC:11992 HGNC
Ensembl ENSG00000177302 Ensembl
AllianceGenome HGNC:11992
DescrptionSourceLinks
IDGenomeChromosomeStartEndLength
ENST00000321105.10 hg38 chr17 18,271,428 18,314,994 43,567
ENST00000321105.10 hg19 chr17 18,174,742 18,218,308 43,567
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