Thioguanine
Information
- Drug Name
- Thioguanine
- Description
- Entry(CIViC)
- 22
CIViC
Annotation
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT02723994 | Active, not recruiting | Phase 2 | A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia | September 30, 2016 | February 1, 2026 |
| NCT02521493 | Active, not recruiting | Phase 3 | Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome | December 23, 2015 | June 30, 2024 |
| NCT02828358 | Active, not recruiting | Phase 2 | Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement | April 1, 2017 | September 22, 2024 |
| NCT02883049 | Active, not recruiting | Phase 3 | Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations | February 29, 2012 | September 22, 2024 |
| NCT02101853 | Active, not recruiting | Phase 3 | Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia | December 17, 2014 | September 22, 2024 |
| NCT01228331 | Active, not recruiting | Phase 2/Phase 3 | Clofarabine or High-Dose Cytarabine and Pegaspargase in Children With ALL | October 2010 | December 2024 |
| NCT02112916 | Active, not recruiting | Phase 3 | Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma | October 4, 2014 | September 22, 2024 |
| NCT00408005 | Active, not recruiting | Phase 3 | Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma | January 22, 2007 | March 7, 2025 |
| NCT03117751 | Active, not recruiting | Phase 2/Phase 3 | Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma | March 29, 2017 | March 31, 2028 |
| NCT01190930 | Active, not recruiting | Phase 3 | Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma | August 9, 2010 | March 31, 2028 |
| NCT00003671 | Completed | Phase 2 | Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia | December 1998 | February 2009 |
| NCT00004056 | Completed | Phase 1 | Combination Chemotherapy Followed by Melphalan and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Acute Myeloid Leukemia | October 1999 | March 2007 |
| NCT00002514 | Completed | Phase 3 | Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First Remission | May 7, 1993 | |
| NCT00005585 | Completed | Phase 3 | Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia | April 2000 | |
| NCT00005596 | Completed | Phase 3 | Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia | April 2000 | July 2007 |
| NCT00005603 | Completed | Phase 3 | Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia | March 2000 | |
| NCT00005823 | Completed | Phase 3 | Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome | December 1998 | December 2007 |
| NCT00005945 | Completed | Phase 3 | Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia | June 2000 | June 2008 |
| NCT00016302 | Completed | N/A | Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia | April 2001 | |
| NCT00022126 | Completed | Phase 2 | Combination Chemotherapy With or Without Donor Bone Marrow Transplantation in Treating Infants With Previously Untreated Acute Lymphoblastic Leukemia | November 2002 | April 2006 |
| NCT00075725 | Completed | Phase 3 | Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia | December 29, 2003 | March 31, 2021 |
| NCT00103285 | Completed | Phase 3 | Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia | April 11, 2005 | March 31, 2021 |
| NCT00109837 | Completed | Phase 2 | S0333 Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia | April 2005 | November 2014 |
| NCT00198991 | Completed | Phase 4 | German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003) | April 2003 | June 30, 2013 |
| NCT00199004 | Completed | Phase 4 | Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab | April 2004 | March 2009 |
| NCT00199017 | Completed | Phase 4 | German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults | April 2004 | |
| NCT00199056 | Completed | Phase 4 | German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99) | October 1999 | December 2005 |
| NCT00266136 | Completed | Phase 3 | Biology and Treatment Strategy of AML in Its Subgroups: Multicenter Randomized Trial by the German Acute Myeloid Leukemia Cooperative Group (AMLCG) | June 1999 | October 2012 |
| NCT00369317 | Completed | Phase 3 | Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes | March 2007 | December 31, 2021 |
| NCT00430118 | Completed | Phase 3 | Combination Chemotherapy Based on Risk of Relapse in Treating Young Patients With Acute Lymphoblastic Leukemia | July 2000 | January 2012 |
| NCT00004228 | Completed | Phase 3 | Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma | June 2000 | March 31, 2015 |
| NCT00002517 | Completed | Phase 3 | Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome | March 1993 | |
| NCT00002590 | Completed | Phase 2 | Combination Chemotherapy in Treating Children With Lymphoma | July 1994 | March 2007 |
| NCT00002665 | Completed | Phase 2 | SWOG-9400 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Previously Untreated Acute Lymphocytic Leukemia | July 1995 | December 2003 |
| NCT00002744 | Completed | Phase 3 | Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia | May 1996 | March 2007 |
| NCT00002798 | Completed | Phase 3 | Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome | August 1996 | |
| NCT00002812 | Completed | Phase 3 | Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia | September 1996 | |
| NCT00002816 | Completed | Phase 3 | Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia | December 1996 | April 2006 |
| NCT00002944 | Completed | Phase 3 | Combination Chemotherapy in Treating Children With Progressive Brain Tumors | April 1997 | April 2012 |
| NCT00003593 | Completed | Phase 3 | Chemotherapy in Treating Children With Down Syndrome and Myeloproliferative Disorder, Acute Myelogenous Leukemia, or Myelodysplastic Syndrome | June 1999 | April 2012 |
| NCT00613457 | Completed | Phase 3 | Combination Chemotherapy Based on Risk of Relapse in Treating Young Patients With Acute Lymphoblastic Leukemia | September 2000 | July 2006 |
| NCT00671034 | Completed | Phase 3 | Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia | July 21, 2008 | March 31, 2021 |
| NCT00866307 | Completed | Phase 1 | Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia (Closed to Accrual 4-22-2011) | February 23, 2009 | March 31, 2021 |
| NCT00866749 | Completed | Phase 2 | Augmented Berlin-Frankfurt-Munster (BFM) Therapy for Adolescent/Young Adults With Acute Lymphoblastic Leukemia or Acute Lymphoblastic Lymphoma | September 12, 2006 | July 26, 2018 |
| NCT01117441 | Completed | Phase 3 | International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic Leukemia | June 2010 | December 31, 2021 |
| NCT01156883 | Completed | N/A | Combination Chemotherapy in Treating Young Adult Patients With Acute Lymphoblastic Leukemia | April 2010 | October 31, 2017 |
| NCT01451515 | Completed | Phase 2 | NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma | May 25, 2012 | May 31, 2022 |
| NCT06390319 | Not yet recruiting | Phase 2 | Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL) | June 2024 | December 2033 |
| NCT06317662 | Not yet recruiting | Phase 2 | Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia | July 31, 2024 | December 21, 2027 |
| NCT06124157 | Not yet recruiting | Phase 3 | A Study Comparing the Combination of Dasatinib and Chemotherapy Treatment With or Without Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or Philadelphia Chromosome-Like (Ph-Like) ABL-Class B-Cell Acute Lymphoblastic Leukemia (B-ALL) | July 22, 2024 | December 1, 2030 |
| NCT03007147 | Recruiting | Phase 3 | Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia | August 8, 2017 | September 30, 2027 |
| NCT06336395 | Recruiting | Phase 2 | Ma-Spore ALL 2020 Study | March 4, 2020 | March 2030 |
| NCT03571321 | Recruiting | Phase 1 | Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia | May 28, 2019 | September 5, 2027 |
| NCT03914625 | Recruiting | Phase 3 | A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia | July 3, 2019 | June 30, 2029 |
| NCT03959085 | Recruiting | Phase 3 | Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy | October 31, 2019 | March 31, 2030 |
| NCT04043494 | Recruiting | Phase 3 | International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma | August 23, 2019 | November 22, 2027 |
| NCT04546399 | Suspended | Phase 2 | A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL) | December 4, 2020 | June 30, 2028 |
| NCT03150693 | Suspended | Phase 3 | Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia | June 1, 2017 | August 2025 |
| NCT00275106 | Terminated | Phase 3 | Prednisolone or Dexamethasone Combined With Chemotherapy in Treating Young Patients With Newly Diagnosed Lymphoblastic Lymphoma | September 2004 | August 2012 |
| NCT02419469 | Terminated | Phase 2 | Augmented Berlin-Frankfurt-Munster Therapy Plus Ofatumumab for Young Adults With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma | November 13, 2015 | June 22, 2017 |
| NCT00002531 | Unknown status | Phase 2 | Combination Chemotherapy in Treating Adults With Acute Lymphocytic Leukemia | January 1993 | |
| NCT00764907 | Unknown status | Phase 3 | Risk-Adjusted Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia | November 2002 | |
| NCT00343369 | Unknown status | N/A | Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia | January 2003 | |
| NCT00558519 | Unknown status | Phase 2 | Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia | March 12, 2008 | |
| NCT00550992 | Unknown status | N/A | Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia | January 2006 | |
| NCT00003728 | Unknown status | Phase 3 | Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma | December 1998 | |
| NCT02660762 | Unknown status | Phase 2 | Modified MRCUKALLⅫ/ECOGE2993 Regimen for ALL | January 2016 | January 2019 |
| NCT00002701 | Unknown status | Phase 3 | Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Promyelocytic Leukemia | October 1995 | |
| NCT00002658 | Unknown status | Phase 3 | Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia | January 1994 | |
| NCT02894645 | Unknown status | Phase 4 | Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study | October 2008 | |
| NCT00003423 | Unknown status | Phase 3 | Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma | May 1995 | |
| NCT00003437 | Unknown status | Phase 3 | Hormone Therapy Plus Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia | January 1997 | |
| NCT06210750 | Withdrawn | Phase 2 | Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL) | August 9, 2024 | September 22, 2026 |