RG7112

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Information
Drug Name
RG7112
Description
Entry(CIViC)
2
CIViC
Disease Mutation EL ET ED CS VO TR Pubmed Links
leukemia TP53 WILD TYPE TP53 WILD TYPE B Predictive Supports Sensitivity/Response N/A 3 26459177 Detail
leukemia TP53 DELETERIOUS MUTATION TP53 DELETERIOUS MUTATION B Predictive Supports Resistance Somatic 3 26459177 Detail
Annotation
Description Associated Genes Associated Variants Sensitivity Supported Source Links
Phase I Trial of RG7112 in 116 heavily pretreated ... TP53 TP53 WILD TYPE TP53 WILD TYPE Sensitivity true CIViC Evidence detail
Phase I Trial of MDM2 inhibitor RG7112 in 116 pati... TP53 TP53 DELETERIOUS MUTATION TP53 DELETERIOUS MUTATION Resitance or Non-Reponse true CIViC Evidence detail