Mitomycin-C

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Information
Drug Name
Mitomycin-C
Description
Entry(CIViC)
CIViC
[No Data.]
Annotation
Description Associated Genes Associated Variants Sensitivity Supported Source Links
O(6)-methylguanine DNA-methyltransferase (MGMT) ov... MGMT MGMT OVEREXPRESSION Sensitivity true MMMP detail
Cells were transfected with ATF2 cDNA lacking the ... ATF2 ATF2 UNDEREXPRESSION Sensitivity true MMMP detail
NCT ID Status Phase Summary Start date Completion date
NCT02369458 Active, not recruiting Phase 2 Mitomycin C in Patients With Incurable p16 Positive Oropharyngeal and p16 Negative Head and Neck Squamous Cell Carcinoma (HNSCC) Resistant to Standard Therapies April 14, 2015 June 30, 2024
NCT02805257 Completed Phase 2 Ahmed Glaucoma Valve Surgery With Mitomycin-C June 2016 March 2020
NCT01504282 Completed N/A Mitomycin-c Application for PRK
NCT01296763 Completed Phase 1 Trial of ICM With or Without AZD2281 (Olaparib) in Patients With Advanced Pancreatic Cancer January 2011 February 2016
NCT02016898 Completed Phase 2 The Effect of Sponge Versus No-Sponge Placement of Mitomycin-C on the Outcomes of Trabeculectomy With Ex-PRESS Glaucoma Filtration Device March 2014 January 17, 2017
NCT05688488 Recruiting Phase 1/Phase 2 Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords May 5, 2023 December 31, 2026
NCT05838391 Recruiting N/A Adaptive Radiation in Anal Cancer May 18, 2023 December 31, 2028
NCT02982395 Terminated Phase 3 Study to Evaluate the Efficacy and Safety Of Intravesical Nanoxel®M In BCG Refractory NMIBC January 2017 August 2018
NCT01324141 Terminated Phase 1 Topical MTS-01 for Dermatitis During Radiation and Chemotherapy for Anal Cancer March 18, 2011 April 15, 2015
NCT02030990 Unknown status Phase 2/Phase 3 The Use of MMC During PRK and Its Effect on Postoperative Topical Steroid Requirements August 2014 July 2023
NCT01858025 Unknown status Early Phase 1 Concurrent Chemoradiation + 5-FU + Mitomycin-C in Anal Carcinoma July 2013 December 2019
NCT02989207 Unknown status N/A Surgical Approaches in Treating Uncontrolled Glaucoma in Black African and African-Caribbeans August 2016 December 2017
NCT00386399 Withdrawn Phase 2 Study of Mitomycin-C in Patients With Advanced or Recurrent Pancreatic Cancer With Mutated BRCA2 Gene October 2006 February 2008