Melphalan

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Information
Drug Name
Melphalan
Description
Entry(CIViC)
17
CIViC
Disease Mutation EL ET ED CS VO TR Pubmed Links
pancreatic cancer FANCC LOSS-OF-FUNCTION FANCC LOSS-OF-FUNCTION D Predictive Supports Sensitivity/Response Unknown 3 16243825 Detail
multiple myeloma KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000692768.1, ENST00000693229.1, ENST00000686969.1, ENST00000688940.1 )
B Predictive Supports Resistance Somatic 2 19284554 Detail
multiple myeloma KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000692768.1, ENST00000693229.1, ENST00000686969.1, ENST00000688940.1 )
D Predictive Supports Resistance Somatic 2 11050000 Detail
multiple myeloma KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000692768.1, ENST00000693229.1, ENST00000686969.1, ENST00000688940.1 )
D Predictive Supports Resistance Somatic 2 12483530 Detail
multiple myeloma KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000692768.1, ENST00000693229.1, ENST00000686969.1, ENST00000688940.1 )
D Predictive Supports Resistance Somatic 2 16497971 Detail
multiple myeloma KRAS p.Gly12Asp (p.G12D)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Asp (p.G12D)
( ENST00000692768.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000693229.1 )
B Predictive Supports Resistance Somatic 2 19284554 Detail
multiple myeloma KRAS p.Gly12Asp (p.G12D)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Asp (p.G12D)
( ENST00000692768.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000693229.1 )
D Predictive Supports Resistance Somatic 2 11050000 Detail
multiple myeloma KRAS p.Gly12Asp (p.G12D)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Asp (p.G12D)
( ENST00000692768.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000693229.1 )
D Predictive Supports Resistance Somatic 12483530 Detail
multiple myeloma KRAS p.Gly12Asp (p.G12D)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Asp (p.G12D)
( ENST00000692768.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000693229.1 )
D Predictive Supports Resistance Somatic 2 16497971 Detail
multiple myeloma KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
B Predictive Supports Resistance Somatic 19284554 Detail
multiple myeloma KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
D Predictive Supports Resistance Somatic 2 11050000 Detail
multiple myeloma KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
D Predictive Supports Resistance Somatic 12483530 Detail
multiple myeloma KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
D Predictive Supports Resistance Somatic 2 16497971 Detail
multiple myeloma KRAS p.Gly12Ser (p.G12S)
( ENST00000685328.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ser (p.G12S)
( ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000686969.1, ENST00000556131.2, ENST00000557334.6, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
B Predictive Supports Resistance Somatic 19284554 Detail
multiple myeloma KRAS p.Gly12Ser (p.G12S)
( ENST00000685328.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ser (p.G12S)
( ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000686969.1, ENST00000556131.2, ENST00000557334.6, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
D Predictive Supports Resistance Somatic 2 11050000 Detail
multiple myeloma KRAS p.Gly12Ser (p.G12S)
( ENST00000685328.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ser (p.G12S)
( ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000686969.1, ENST00000556131.2, ENST00000557334.6, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
D Predictive Supports Resistance Somatic 2 12483530 Detail
multiple myeloma KRAS p.Gly12Ser (p.G12S)
( ENST00000685328.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ser (p.G12S)
( ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000686969.1, ENST00000556131.2, ENST00000557334.6, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
D Predictive Supports Resistance Somatic 2 16497971 Detail
Annotation
Description Associated Genes Associated Variants Sensitivity Supported Source Links
In the pancreatic cell lines PL11 (FANCC homozygou... FANCC FANCC LOSS-OF-FUNCTION FANCC LOSS-OF-FUNCTION Sensitivity true CIViC Evidence detail
In a study of patients receiving melphalan-based t... KRAS KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000692768.1, ENST00000693229.1, ENST00000686969.1, ENST00000688940.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000692768.1, ENST00000693229.1, ENST00000686969.1, ENST00000688940.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000692768.1, ENST00000693229.1, ENST00000686969.1, ENST00000688940.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ala (p.G12A)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000692768.1, ENST00000693229.1, ENST00000686969.1, ENST00000688940.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In a study of patients receiving melphalan-based t... KRAS KRAS p.Gly12Asp (p.G12D)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Asp (p.G12D)
( ENST00000692768.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Asp (p.G12D)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Asp (p.G12D)
( ENST00000692768.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Asp (p.G12D)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Asp (p.G12D)
( ENST00000692768.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Asp (p.G12D)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Asp (p.G12D)
( ENST00000692768.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In a study of patients receiving melphalan-based t... KRAS KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Cys (p.G12C)
( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In a study of patients receiving melphalan-based t... KRAS KRAS p.Gly12Ser (p.G12S)
( ENST00000685328.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ser (p.G12S)
( ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000686969.1, ENST00000556131.2, ENST00000557334.6, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Ser (p.G12S)
( ENST00000685328.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ser (p.G12S)
( ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000686969.1, ENST00000556131.2, ENST00000557334.6, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Ser (p.G12S)
( ENST00000685328.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ser (p.G12S)
( ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000686969.1, ENST00000556131.2, ENST00000557334.6, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
In in vitro experiments, myeloma cell lines expres... KRAS KRAS p.Gly12Ser (p.G12S)
( ENST00000685328.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 ) KRAS p.Gly12Ser (p.G12S)
( ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000686969.1, ENST00000556131.2, ENST00000557334.6, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
Resitance or Non-Reponse true CIViC Evidence detail
The consistent synergy seen for imexon and alkylat... ROS1 ROS1 OVEREXPRESSION Sensitivity true MMMP detail
In patients treated with melphalan based isolated ... PIK3C2A PIK3C2A EXPRESSION toxicity increased true MMMP detail
NCT ID Status Phase Summary Start date Completion date
NCT04339101 Active, not recruiting Phase 2 Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation November 11, 2020 May 22, 2024
NCT01526096 Active, not recruiting Phase 1 Stem Cell Transplantation for Patients With Multiple Myeloma July 12, 2011 September 12, 2025
NCT03346135 Active, not recruiting Phase 2 Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma July 17, 2019 July 17, 2025
NCT00003042 Active, not recruiting Phase 2 Chemotherapy and Stem Cell Transplantation in Treating Patients With Stage IIIB Breast Cancer May 30, 1997 December 30, 2024
NCT04872595 Active, not recruiting Phase 2 A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant April 30, 2021 April 2025
NCT01476839 Active, not recruiting Phase 1 Radiolabeled Monoclonal Antibody Therapy and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Primary Refractory or Relapsed Hodgkin Lymphoma November 9, 2012 December 31, 2024
NCT00114101 Active, not recruiting Phase 3 Lenalidomide in Treating Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant December 15, 2004 February 22, 2025
NCT02195479 Active, not recruiting Phase 3 A Study of Combination of Daratumumab and Velcade (Bortezomib) Melphalan-Prednisone (DVMP) Compared to Velcade Melphalan-Prednisone (VMP) in Participants With Previously Untreated Multiple Myeloma December 9, 2014 June 30, 2024
NCT04395222 Active, not recruiting Phase 2 Tocilizumab for the Prevention of Graft Failure and GVHD in Haplo-Cord Transplantation October 7, 2020 May 2027
NCT04191187 Active, not recruiting Phase 2 Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies December 6, 2019 February 2025
NCT02866136 Active, not recruiting Phase 2 Conservative Treatments of Retinoblastoma February 2012 September 2035
NCT02061800 Active, not recruiting Phase 1/Phase 2 CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant June 3, 2013 July 2026
NCT03786783 Active, not recruiting Phase 2 Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma March 4, 2019 September 22, 2024
NCT01175356 Active, not recruiting Phase 1 Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin October 4, 2010 September 28, 2024
NCT04342572 Active, not recruiting Phase 1 Intra-arterial Chemotherapy for Retinoblastoma August 11, 2020 January 4, 2025
NCT01163357 Active, not recruiting Phase 1 Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma January 28, 2011 December 31, 2024
NCT01885689 Active, not recruiting Phase 2 Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia February 10, 2014 December 30, 2024
NCT03691376 Active, not recruiting Phase 1 Genetically Engineered Cells (NY-ESO-1 TCR Engineered T Cells and HSCs) After Melphalan Conditioning Regimen in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer March 8, 2019 January 24, 2027
NCT03849651 Active, not recruiting Phase 2 TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies January 31, 2019 July 1, 2025
NCT03342196 Active, not recruiting Phase 2 Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor Transplantation March 21, 2018 June 9, 2025
NCT03292263 Active, not recruiting Phase 1/Phase 2 ASCT With Nivolumab in Patients With Multiple Myeloma April 24, 2017 December 30, 2024
NCT01091831 Active, not recruiting Phase 3 Cyclophosphamide, Lenalidomide and Dexamethasone (CRD) Versus Melphalan (200 mg/m2) Followed By Autologous Stem Cell Transplant (ASCT) In Newly Diagnosed Multiple Myeloma Subjects July 2009 December 2024
NCT01857934 Active, not recruiting Phase 2 Therapy for Children With Advanced Stage Neuroblastoma July 5, 2013 December 2024
NCT01085617 Active, not recruiting Phase 3 Standard Chemotherapy With or Without Nelarabine or Rituximab in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia December 2010 December 2025
NCT03259503 Active, not recruiting Phase 1 Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant September 13, 2019 July 31, 2024
NCT03188172 Active, not recruiting Phase 2 MUK Nine b: OPTIMUM Treatment Protocol September 28, 2017 May 31, 2026
NCT02797470 Active, not recruiting Phase 1/Phase 2 Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant June 23, 2016 June 30, 2025
NCT02443077 Active, not recruiting Phase 3 Ibrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma October 12, 2016 May 10, 2025
NCT03004287 Active, not recruiting Phase 2 2015-12: A Study Exploring the Use of Early and Late Consolidation/Maintenance Therapy July 1, 2017 October 2025
NCT03742297 Active, not recruiting Phase 3 Treatment for Elderly Fit Newly Diagnosed Multiple Myeloma Patients Aged Between 65 and 80 Years October 22, 2018 January 2031
NCT01840566 Active, not recruiting Phase 1 High Dose Therapy and Autologous Stem Cell Transplantation Followed by Infusion of Chimeric Antigen Receptor (CAR) Modified T-Cells Directed Against CD19+ B-Cells for Relapsed and Refractory Aggressive B Cell Non-Hodgkin Lymphoma April 2013 April 2025
NCT03674411 Active, not recruiting Phase 2 Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy January 2, 2019 June 28, 2024
NCT03821610 Active, not recruiting Phase 2 A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With Fludarabine and Melphalan Reduced Intensity Conditioning in Adults With Acute Lymphoblastic Leukaemia (ALL) in Complete Remission. (ALL-RIC) November 22, 2018 November 22, 2027
NCT02415413 Active, not recruiting Phase 2 Carfilzomib in Treatment Patients Under 65 Years With High Risk Smoldering Multiple Myeloma May 2015 June 2027
NCT01054196 Active, not recruiting Phase 1/Phase 2 Lenalidomide Plus Melphalan as a Preparative Regimen for Autologous Stem Cell Transplantation in Relapsed Multiple Myeloma: A Phase 1 / 2 Study August 2010 December 2024
NCT01810588 Active, not recruiting Phase 2 Targeting the IPA and Matching for the Non-Inherited Maternal Antigen for Haplo-Cord Transplantation October 16, 2012 April 2028
NCT00871013 Active, not recruiting Phase 2 Trial for Patients Not Qualifying for TT4 and TT5 Protocols Because of Prior Therapy March 2009 December 2024
NCT01798004 Active, not recruiting Phase 1 Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma April 8, 2013
NCT01758328 Active, not recruiting Phase 1 Dose Escalation Trial of WT1-specific Donor-derived T Cells Following T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Relapsed/Refractory Multiple Myeloma December 2012 December 2024
NCT02342782 Active, not recruiting Phase 1 Yttrium Y 90 Basiliximab and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Mature T-cell Non-Hodgkin Lymphoma June 8, 2020 December 31, 2024
NCT02251821 Active, not recruiting Phase 2 JAK Inhibitor Before Donor Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis October 20, 2014 December 28, 2025
NCT00869232 Active, not recruiting Phase 2 UARK 2008-02 A Trial for High-risk Myeloma Evaluating Accelerating and Sustaining Complete Remission October 2008 October 2024
NCT00716066 Active, not recruiting Phase 2 Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases June 2008 January 31, 2030
NCT00638898 Active, not recruiting Phase 1 Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor February 26, 2007 December 30, 2024
NCT03352765 Active, not recruiting Phase 1 A Phase I Study of Bendamustine and Melphalan Conditioning and Autologous Stem Cell Transplantation for Treatment of Multiple Myeloma and Relapsed/Refractory B-cell Lymphoma in Elderly Patients November 20, 2017 November 2024
NCT02909036 Active, not recruiting Phase 1 Study of Captisol Enabled Melphalan and Pharmacokinetics for Patients With Multiple Myeloma or Light Chain Amyloidosis That Are Receiving an Autologous Transplant. September 2016 September 2024
NCT00602641 Active, not recruiting Phase 3 Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma February 29, 2008 February 22, 2025
NCT00544115 Active, not recruiting Phase 2 Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders October 16, 2001 December 30, 2024
NCT00544466 Active, not recruiting Phase 1/Phase 2 Helical Tomotherapy, Fludarabine Phosphate, and Melphalan Followed By Allo-HSCT in Hematological Malignancies July 31, 2006 December 30, 2024
NCT01729091 Active, not recruiting Phase 2 Umbilical Cord Blood-Derived Natural Killer Cells, Elotuzumab, Lenalidomide, and High Dose Melphalan, Followed by Stem Cell Transplant in Treating Patients With Multiple Myeloma June 10, 2013 June 30, 2025
NCT04473911 Active, not recruiting Phase 1 Haplo Peripheral Blood Sct In GVHD Prevention August 14, 2020 October 2024
NCT02896582 Active, not recruiting Phase 2 Efficacy of Upfront and Maintenance Obinutuzumab in Mantle Cell Lymphoma Treated by DHAP and MRD Driven Maintenance October 2016 March 2025
NCT00551928 Active, not recruiting Phase 3 Lenalidomide Melphalan and Prednisone Versus High Dose Melphalan in Newly Diagnosed Multiple Myeloma Patients June 2007 June 2025
NCT00004165 Completed Phase 3 Melphalan Followed by Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma October 1999 August 2003
NCT00004188 Completed Phase 3 Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma February 2001
NCT00004250 Completed Phase 2 Isolated Limb Infusion of Chemotherapy in Treating Patients With Melanoma or Soft Tissue Sarcoma of the Arm or Leg That Cannot Be Removed By Surgery August 1999
NCT00004921 Completed Phase 3 High-Dose Chemotherapy Compared With Standard Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer That Has Been Removed During Surgery September 1998 September 2007
NCT00005589 Completed Phase 3 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation With or Without Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma October 1999 April 2013
NCT00005792 Completed Phase 1 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma June 2, 1998 November 1, 2018
NCT00005803 Completed Phase 1/Phase 2 Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma September 1999 October 2018
NCT00005835 Completed Phase 1 N99-02: Melphalan and Buthionine Sulfoximine August 2001 April 2016
NCT00005978 Completed Phase 1 N99-01: Combination Chemotherapy, Radiation Therapy, and Stem Cell Transplantation in Treating Patients With Neuroblastoma May 2000
NCT00006244 Completed Phase 2 Melphalan, Peripheral Stem Cell Transplantation, and Interleukin-2 Followed by Interferon Alfa in Treating Patients With Advanced Multiple Myeloma February 2000 April 2016
NCT00006695 Completed Phase 2 Monoclonal Antibody Therapy, Combination Chemotherapy, and Peripheral Stem Cell Transplant in Non-Hodgkin's Lymphoma April 1, 2000 December 16, 2014
NCT00006747 Completed Phase 2 Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphoma November 2000 February 2003
NCT00007852 Completed Phase 2 Rituximab & Combination Chemotherapy Followed by Transplantation in Relapsed or Refractory Non-Hodgkin's Lymphoma September 1, 2000 January 1, 2011
NCT00007995 Completed Phase 2 Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Patients Who Have Multiple Myeloma or Primary Systemic Amyloidosis July 1999 May 2008
NCT00008190 Completed Phase 2 Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Acute Leukemia March 1999 May 2008
NCT00008229 Completed Phase 3 Melphalan With or Without Holmium Ho 166 DOTMP Followed by Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma August 2000 September 2001
NCT00008268 Completed Phase 2 Melphalan and Filgrastim to Stimulate Peripheral Stem Cells in Patients With Multiple Myeloma August 2000 June 2003
NCT00012051 Completed Phase 3 Chemotherapy and Peripheral Stem Cell Transplant With or Without Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma September 2000 October 2007
NCT00014469 Completed Phase 2 Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Advanced Hematologic Cancer December 2000 May 2007
NCT00014508 Completed Phase 2 Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma November 19, 2001 May 27, 2011
NCT00017225 Completed Phase 2 Chemotherapy and Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma May 1997 February 2002
NCT00017368 Completed Phase 2 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Neuroblastoma April 2001 January 2012
NCT00017680 Completed Phase 2 Study of High-Dose Melphalan and Autologous Stem Cell Transplantation in Patients With Primary Light Chain Amyloidosis July 1999 April 2004
NCT00019097 Completed Phase 2 Vaccine Therapy in Treating Patients With Multiple Myeloma July 1995 March 2007
NCT00019760 Completed Phase 2 Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver April 1999 March 2002
NCT00019786 Completed Phase 2 Isolated Hepatic Perfusion With Melphalan in Treating Patients With Primary Unresectable Liver Cancer or Liver Metastases August 1999 January 2006
NCT00019968 Completed Phase 2 Isolated Limb Perfusion of Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Soft Tissue Sarcoma of the Arm or Leg August 1999 March 2002
NCT00020501 Completed Phase 3 Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver March 2001 January 2005
NCT00025649 Completed Phase 2 Combination Chemotherapy Followed by Surgery and Peripheral Stem Cell or Bone Marrow Transplantation in Treating Infants With Newly Diagnosed Neuroblastoma July 1999 March 2009
NCT00027560 Completed Phase 2 Melphalan, Fludarabine, and Alemtuzumab Followed by Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer July 2001 April 2009
NCT00027937 Completed Phase 2 Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Biological Therapy in Treating Patients With Solid Tumors or Lymphoma August 2001 November 2007
NCT00028600 Completed Phase 2 Peripheral Stem Cell Transplant in Treating Patients With Multiple Myeloma November 2001 February 2010
NCT00030082 Completed Phase 1 Hepatic Arterial Infusion With Melphalan in Treating Patients With Unresectable Liver Cancer July 2001
NCT00038831 Completed Phase 1/Phase 2 Allo Transplantation With Mylotarg, Fludarabine and Melphalan for AML, CML and MDS May 2001 October 2006
NCT00038857 Completed Phase 2 Megadose CD34 Selected Progenitor Cells for Transplantation in Patients With Advanced Hematological Malignant Diseases September 2001 June 2009
NCT00040937 Completed Phase 2 S0204 Thalidomide, Chemotherapy, and Peripheral Stem Cell Transplant in Treating Patients With Multiple Myeloma June 2002 October 2015
NCT00043979 Completed Phase 2 Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas September 19, 2002 December 14, 2011
NCT00045136 Completed Phase 1/Phase 2 Chemotherapy, Holmium Ho 166 DOTMP, and Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma January 2002
NCT00046852 Completed Phase 1/Phase 2 Chemotherapy and Peripheral Stem Cell Transplantation Followed By Immunotherapy in Treating Patients With Multiple Myeloma December 2001 February 2008
NCT00054353 Completed Phase 1/Phase 2 Reduced-Intensity Conditioning Followed By Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma October 2002 October 14, 2012
NCT00055653 Completed Phase 2 Donor Umbilical Cord Blood Transplantation in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders January 2003 September 2005
NCT00058292 Completed Phase 1 Radiolabeled Monoclonal Antibody Therapy and High-Dose Chemotherapy Followed By Autologous Peripheral Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma April 2000 March 2009
NCT00060255 Completed Phase 2 High-Dose Chemotherapy, Total-Body Irradiation, and Autologous Stem Cell Transplantation or Bone Marrow Transplantation in Treating Patients With Hematologic Cancer or Solid Tumors December 1991 February 2013
NCT00064337 Completed Phase 2 S0115, High-Dose Melphalan and Autologous Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma or Primary Systemic Amyloidosis January 2004 November 2015
NCT00067002 Completed Phase 2 Randomized Double Cord Blood Transplant Study April 2003 July 2016
NCT00070187 Completed Phase 2/Phase 3 Immunotherapy Using Cyclosporine, Interferon Gamma, and Interleukin-2 After High-Dose Myeloablative Chemotherapy With Autologous Stem Cell Transplantation in Treating Patients With Refractory or Relapsed Hodgkin's Lymphoma November 2003
NCT00070200 Completed Phase 1 Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive Neuroblastoma March 2004 December 2013
NCT00075621 Completed Phase 2 Tandem Autologous Stem Cell Transplantation in Treating Patients With Primary Systemic (AL) Amyloidosis August 2000 September 4, 2020
NCT00080886 Completed Phase 2 Rituximab, Carmustine; Cytarabine, Etoposide, & Melphalan; Stem Cell Transplantation for Non-Hodgkin's Lymphoma May 8, 2002 March 12, 2015
NCT00083551 Completed Phase 3 UARK 98-026 TT II: Multiple Myeloma Evaluating Anti-Angiogenesis With Thalidomide and Post-Transplant Consolidation Chemotherapy August 1998 August 2014
NCT00083915 Completed Phase 3 DTPACE Followed by Tandem Transplant With Melphalan (MEL) 200 Versus MEL/Dexamethasone/Thalidomide (DT) Platinol/Adriamycin/Etoposide (PACE) Hybrid and DTPACE Consolidation June 2001 June 2010
NCT00089167 Completed Phase 2 Melphalan, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed, Previously Untreated Primary Systemic Amyloidosis May 2002
NCT00089401 Completed Phase 2 Isolated Hepatic Perfusion With Melphalan in Treating Patients With Unresectable Colorectal Cancer That Has Metastasized to the Liver July 2004 March 2008
NCT00089453 Completed Phase 1 Study of KIR-Ligand Mismatched Haplo-Identical Natural Killer Cells Transfused Before Autologous Stem Cell Transplant September 2003 May 2010
NCT00096083 Completed Phase 2 Hepatic Arterial Infusion of Melphalan With Hepatic Perfusion in Treating Patients With Unresectable Liver Cancer September 2004 August 2012
NCT00103298 Completed Phase 2 Isolated Hepatic Perfusion With Melphalan Followed by Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer December 2004 July 2006
NCT00104975 Completed Phase 1 Alemtuzumab and Combination Chemotherapy Followed By Donor Lymphocytes in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer February 2005 May 2008
NCT00112645 Completed Phase 1 Donor Stem Cell Transplant in Treating Young Patients With Relapsed or Refractory Solid Tumors April 2005 February 2011
NCT00112827 Completed Phase 1/Phase 2 Melphalan and Radiation Therapy Followed By Lenalidomide in Treating Patients Who Are Undergoing Autologous Stem Cell Transplant for Stage I, Stage II, or Stage III Multiple Myeloma November 2004 February 15, 2019
NCT00133367 Completed Phase 2 Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus August 2005 November 2011
NCT00137995 Completed Phase 3 R-ICE Versus R-DHAP in Patients Aged 18-65 With Relapse Diffuse Large B-cell Lymphoma June 2003 October 2008
NCT00165139 Completed Phase 2 Intensive Chemo-Radiotherapy With Peripheral Blood Progenitor Cell Rescue for Children With Advanced Neuroblastoma and Sarcomas January 1996 February 2009
NCT00176865 Completed Phase 2 Stem Cell Transplant for Immunologic or Histiocytic Disorders August 2002 August 2014
NCT00177047 Completed Phase 2/Phase 3 Autologous Transplant for Multiple Myeloma April 20, 2004 August 1, 2020
NCT00182793 Completed Phase 2 Combination Chemotherapy With or Without Trastuzumab Followed By an Autologous Stem Cell Transplant and Radiation Therapy in Treating Patients With Stage III or Stage IV Breast Cancer July 2005 October 2014
NCT00185614 Completed Phase 2 Non-myeloablative Allogeneic Transplantation for the Treatment of Multiple Myeloma August 2000 April 2010
NCT00202917 Completed Phase 1/Phase 2 Haploidentical Transplantation With CD3/CD19 Depleted Grafts in Patients With Hematologic Malignancies February 2004 December 2010
NCT00205764 Completed Phase 3 Tandem High Dose Melphalan Versus Triple Intermediate Dose Melphalan and Stem Cell Transplantation in Induction Phase and Prednisolone/IFN Versus IFN in Maintenance Therapy March 1999 October 2009
NCT00217438 Completed Phase 3 Melphalan and Amifostine Followed By One or Two Autologous or Syngeneic Stem Cell Transplants and Maintenance Therapy in Treating Patients With Stage II-III Multiple Myeloma July 2005
NCT00233987 Completed Phase 2 S0410 Tandem Stem Cell Transplantation in Treating Patients With Progressive or Recurrent Hodgkin's Lymphoma October 2005 December 2017
NCT00238433 Completed Phase 2 Busulfan, Melphalan, and Thiotepa in Treating Patients Who Are Undergoing an Autologous Stem Cell Transplant for Hodgkin's or Non-Hodgkin's Lymphoma March 2005 December 2016
NCT00244946 Completed Phase 1 Combination Chemotherapy Followed By Autologous Stem Cell Transplant, and White Blood Cell Infusions in Treating Patients With Non-Hodgkin's Lymphoma March 2004 March 2013
NCT00248430 Completed Phase 1/Phase 2 Donor White Blood Cell Infusions and Interleukin-2 in Treating Patients Who Are Undergoing an Autologous Stem Cell Transplant for Relapsed Advanced Lymphoid Cancer August 2003 July 2007
NCT00253435 Completed Phase 2 N2001-02: I-MIBG With Intensive Chemotherapy and Autologous Stem Cell Rescue for High-Risk Neuroblastoma September 2005 December 2013
NCT00265889 Completed Phase 2 Autologous Stem Cell Transplant in Treating Patients With Progressive or Recurrent Hodgkin's Lymphoma February 2002 April 2010
NCT00275015 Completed Phase 2 Cyclophosphamide and Total Body Irradiation in Treating Patients Who Are Undergoing an Autologous Peripheral Stem Cell Transplant For Chronic Lymphocytic Leukemia January 1998 April 2012
NCT00276809 Completed Phase 2 Combination Chemotherapy, Total-Body Irradiation, and Alemtuzumab in Treating Patients Undergoing an Autologous Stem Cell Transplant for Stage I, Stage II, Stage III, or Stage IV Chronic Lymphocytic Leukemia June 2001 September 2004
NCT00303849 Completed Phase 1/Phase 2 Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors September 15, 2005 March 12, 2021
NCT00305812 Completed Phase 2 Lenalidomide and Melphalan in Treating Patients With Previously Untreated Multiple Myeloma March 9, 2006 June 30, 2008
NCT00307086 Completed Phase 2 Bortezomib Followed by High-Dose Melphalan and Bortezomib as Conditioning Regimen for Tandem Stem Cell Transplants June 2005 March 2012
NCT00313625 Completed Phase 2 Melphalan and Busulfan Followed By Donor Peripheral Stem Cell Transplant, Tacrolimus, and Methotrexate in Treating Patients With Multiple Myeloma September 2005
NCT00317811 Completed Phase 2 Bortezomib, Ascorbic Acid, and Melphalan in Treating Patients With Newly Diagnosed Multiple Myeloma November 2005
NCT00324727 Completed Phase 3 Hepatic Arterial Infusion With Melphalan Compared With Standard Therapy in Treating Patients With Unresectable Liver Metastases Due to Melanoma February 2006 August 2012
NCT00325416 Completed Phase 1/Phase 2 Study of Melphalan and Topotecan (MT) Followed by Autologous Stem Cell Rescue in Patients With Multiple Myeloma. November 19, 2001 January 30, 2018
NCT00344526 Completed Phase 3 Intensive Versus Conventional Treatment in Patients With Primary Amyloidosis January 2000 June 2006
NCT00349778 Completed Phase 2 High-Dose Sequential Therapy and Single Autologous Transplantation for Multiple Myeloma August 2006 April 2010
NCT00357396 Completed Phase 2 Busulfan, Melphalan, and Thiotepa Followed By a Donor Stem Cell Transplant in Treating Patients With High-Risk Ewing's Tumors June 2005 October 2009
NCT00365755 Completed Phase 3 Combination Chemotherapy in Treating Young Patients Who Are Undergoing Surgery and an Autologous Bone Marrow Transplant for Disseminated Neuroblastoma March 2008
NCT00383448 Completed Phase 2 HSCT for High Risk Inherited Inborn Errors September 2006 September 2014
NCT00385788 Completed Phase 2 Allogeneic Blood Stem Cell Transplantation and Adoptive Immunotherapy for Hodgkin's Disease July 2005 August 2016
NCT00388635 Completed Phase 1/Phase 2 Velcade-Melphalan-Prednisone in Older Untreated Multiple Myeloma Patients. April 2004 December 2008
NCT00392691 Completed Phase 1 Melphalan, Yttrium Y 90 Ibritumomab Tiuxetan, and Rituximab Followed by Autologous Stem Cell Transplant in Treating Older Patients With Non-Hodgkin's Lymphoma That Has Relapsed or Not Responded to Previous Treatment October 2006 May 2013
NCT00405756 Completed Phase 3 A Study to Compare MPR With MP in Newly Diagnosed Multiple Myeloma Subjects 65 Years Old or Older. January 2007 April 2016
NCT00406978 Completed Phase 1/Phase 2 Melphalan, Prednisone, Thalidomide and Defibrotide in Relapsed Multiple Myeloma Patients February 2006 April 2014
NCT00410982 Completed Phase 1 Gemcitabine Plus Busulfan, Melphalan and Hematopoietic Cell Transplant for Advanced Lymphoid Malignancies December 2006 September 2012
NCT00421811 Completed Phase 1/Phase 2 A Study of ADH-1 in Combination With Normothermic Isolated Limb Infusion of Melphalan April 2007 March 2009
NCT00423514 Completed Phase 1/Phase 2 Clofarabine, Melphalan, and Thiotepa Followed By a Donor Stem Cell Transplant in Treating Patients With High-Risk and/or Advanced Hematologic Cancer or Other Disease November 20, 2006 June 18, 2021
NCT00423709 Completed N/A Allogeneic Blood Stem Cell Transplantation January 1998 August 2007
NCT00427557 Completed Phase 2 Cellular Therapy With Cord Blood Cells October 2006 November 2010
NCT00427765 Completed Phase 2 Busulfan Plus Melphalan Conditioning Regimen for Lymphoid Malignancies or Multiple Myeloma December 2004 November 2010
NCT00429572 Completed Phase 2 Mini-Allogeneic Peripheral Blood Progenitor Cell Transplantation For Recurrent or Metastatic Breast Cancer January 1998 May 2008
NCT00439556 Completed Phase 2 Bortezomib and Chemotherapy in Treating Participants With Lymphoid Malignancies Undergoing Stem Cell Transplant February 13, 2007 June 7, 2018
NCT00454480 Completed Phase 2/Phase 3 Combination Chemotherapy With or Without Gemtuzumab Ozogamicin or Tipifarnib in Treating Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes August 2006
NCT00469209 Completed Phase 1/Phase 2 Velcade, Trisenox, Vitamin C and Melphalan for Myeloma Patients June 2006 December 2008
NCT00472056 Completed Phase 2 Rituximab in Addition to Autologous Transplantation With BEAM for Patients With Lymphoid Malignancies March 2005 June 2012
NCT00477035 Completed Phase 1 Post-transplant Autologous Cytokine-induced Killer (CIK) Cells for Treatment of High Risk Hematologic Malignancies May 2006 March 2011
NCT00477750 Completed Phase 1/Phase 2 Melphalan, Prednisone, and Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma June 2005 August 5, 2013
NCT00477815 Completed Phase 1 Rituximab, Yttrium Y 90 Ibritumomab Tiuxetan, Melphalan, and Autologous Peripheral Stem Cell Transplant in Treating Patients With Previously Treated Multiple Myeloma May 31, 2005 May 7, 2018
NCT00477971 Completed Phase 3 Low-Dose Melphalan and Dexamethasone Compared With High-Dose Melphalan Followed By Autologous Stem Cell Transplant in Treating Patients With Primary Systemic Amyloidosis October 2005 December 2014
NCT00482846 Completed Phase 1 Melphalan and Palifermin in Treating Patients Undergoing An Autologous Peripheral Stem Cell Transplant for Stage II or III Multiple Myeloma June 2007 September 2012
NCT00498316 Completed Phase 1 Cord Blood Expansion on Mesenchymal Stem Cells July 3, 2007 October 2016
NCT00505895 Completed Phase 2 FM 140 vs FM100 Study in Patients With Multiple Myeloma January 2002 May 2013
NCT00506129 Completed Phase 2 Allogeneic Transplantation in Patients With Cutaneous T-Cell Lymphoma September 2003 June 2015
NCT00507416 Completed Phase 3 Velcade,Thalidomide, and Dexamethasone Versus Velcade and Dexamethasone Versus Velcade, Melphalan, and Prednisone June 2007 March 2013
NCT00520767 Completed Phase 2 Bortezomib, Melphalan, and Dexamethasone in Treating Patients With Primary Amyloidosis or Light Chain Deposition Disease September 2007 June 6, 2019
NCT00521014 Completed Phase 2 GM-CSF and Rituximab After Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Follicular Non-Hodgkin Lymphoma October 2007 July 2013
NCT00536601 Completed N/A High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors June 29, 2006 July 9, 2018
NCT00536978 Completed Phase 2 Natural Killer (NK) Cell Adback After Allogeneic Stem Cell Transplant With Campath-IH Plus Chemorx for Patients With Lymphoid Malignancies September 2007 November 2010
NCT00544570 Completed N/A High-Dose Chemotherapy in Treating Patients Undergoing Stem Cell Transplant for Recurrent or Refractory Hodgkin's Lymphoma April 1998 December 2007
NCT00547196 Completed N/A AlloHCT From Matched Unrelated Donors in Pts w/ Advanced Hematologic Malignancies & Disorders August 16, 2005 May 28, 2024
NCT00550784 Completed Phase 1 Combination Chemotherapy and Autologous Peripheral Stem Cell Transplant in Treating Patients With Stage III, Stage IV, or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer January 2001 October 2014
NCT02497404 Completed Phase 2 Azacytidine Prior to in Vivo T-cell Depleted Allo Stem Cell Transplant for Patients With Myeloid Malignancies in CR February 13, 2015 June 17, 2021
NCT00001576 Completed Phase 1 A Phase I Study of Isolated Hepatic Perfusion With Escalating Dose Melphalan Followed by Postoperative Hepatic Arterial Floxuridine and Leucovorin for Metastatic Unresectable Colorectal Cancers of the Liver July 1997 March 2002
NCT00001587 Completed Phase 1 A Phase I Study of Isolated Hepatic Portal and Arterial Perfusion (IHP) With Escalating Dose Melphalan for Primary or Metastatic Unresectable Cancers of the Liver September 1997 March 2001
NCT00002548 Completed Phase 3 SWOG-9321 Melphalan, TBI, and Transplant vs Combo Chemo in Untreated Myeloma January 1994 November 2006
NCT00002556 Completed Phase 3 Combination Chemotherapy With or Without High Dose Cyclophosphamide and Recombinant Interferon Alfa-2b in Treating Patients With Previously Untreated Stage I-III Multiple Myeloma July 1994
NCT00002594 Completed Phase 2 Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors September 1994 March 2007
NCT00002601 Completed Phase 2 Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma September 1994 September 2014
NCT00002630 Completed Phase 2 High-Dose Melphalan, Total-Body Irradiation, and Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma in First Relapse June 1993 May 2001
NCT00002678 Completed Phase 3 Combination Chemotherapy in Treating Patients With Multiple Myeloma June 2, 1995 December 21, 2009
NCT00002680 Completed Phase 2 Sequential High-Dose Chemotherapy and Stem Cell Transplantation in Treating Patients With Chemotherapy-Sensitive Metastatic Breast Cancer February 1994 December 2000
NCT00002730 Completed Phase 1 Chemotherapy in Treating Children With Neuroblastoma June 1996
NCT00002750 Completed Phase 1 Melphalan in Patients With Neoplastic Meningitis December 1992 May 2001
NCT00002802 Completed Phase 3 Therapy Based on Stage of Disease and Risk Assessment in Treating Children With Neuroblastoma July 1990 September 2003
NCT00002810 Completed Phase 2 High-Dose Melphalan Followed by Peripheral Stem Cell Transplant in Treating Patients With Amyloidosis May 1996 May 2006
NCT00002835 Completed Phase 3 Combination Chemotherapy in Treating Patients With Lymphoma October 30, 1995 February 4, 2004
NCT00002945 Completed Phase 3 High Dose Chemotherapy, Peripheral Stem Cell Transplantation, and Interleukin-2 in Treating Patients With Acute Myeloid Leukemia December 1996 August 2011
NCT00002973 Completed Phase 2 Melphalan and Whole-Body Hyperthermia in Treating Patients With Advanced Melanoma December 1995 December 2000
NCT00002977 Completed Phase 1 Melphalan and Thiotepa Followed by Peripheral Stem Cell Transplantation in Treating Patients With Epithelial Ovarian Cancer in Complete Remission January 1997
NCT00002982 Completed Phase 2 Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Older Patients With Refractory or Relapsed Intermediate-Grade Non-Hodgkin's Lymphoma January 1997 October 2005
NCT00003007 Completed Phase 2 Interferon Alfa Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Multiple Myeloma July 1996 January 2004
NCT00003080 Completed Phase 1 Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Persistent or Platinum Refractory Stage III or IV Ovarian Cancer September 1996 May 2001
NCT00003081 Completed Phase 1 Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Radiation Therapy in Treating Patients With Ewing's Sarcoma, Peripheral Primitive Neuroectodermal Tumor, or Rhabdomyosarcoma March 1998 January 2002
NCT00003146 Completed Phase 2 Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma November 1997 June 2001
NCT00003199 Completed Phase 2 Combination Chemotherapy and Peripheral Blood Stem Cell Transplant Followed By Aldesleukin and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast Cancer November 1997 December 2009
NCT00003215 Completed Phase 3 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Aggressive Non-Hodgkin's Lymphoma April 1997 March 2004
NCT00003335 Completed Phase 2 Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer January 1998 January 2012
NCT00003336 Completed Phase 2 Pilot Study Of Unrelated UCB Transplant for Non-Malignant Hematologic Conditions January 1998 February 2006
NCT00003353 Completed Phase 2 High-Dose Melphalan Plus Peripheral Stem Cell Transplantation in Treating Patients With Primary Systemic Amyloidosis November 16, 1998
NCT00003392 Completed Phase 2 High-Dose Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Metastatic Breast Cancer September 1997 January 2003
NCT00003396 Completed Phase 2 Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer September 1998 December 2002
NCT00003397 Completed Phase 2 Peripheral Stem Cell Transplantation Plus Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma September 1998 December 2002
NCT00003399 Completed Phase 2 Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Multiple Myeloma September 1998 September 2002
NCT00003400 Completed Phase 2 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Prostate Cancer September 1998 March 2000
NCT00003401 Completed Phase 2 Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Multiple Myeloma January 1999 September 2002
NCT00003402 Completed Phase 2 Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia January 1999 December 2002
NCT00003413 Completed Phase 2 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer September 1998 February 2001
NCT00003416 Completed Phase 2 S9805, High-Dose Melphalan Plus Peripheral Stem Cell Transplantation Followed by Interferon Alfa in Treating Patients With Waldenstrom's Macroglobulinemia September 1998 January 2004
NCT00003425 Completed Phase 1/Phase 2 Phase I/II Study of Escalating-Dose Melphalan w/Autologous SCS & Amifostine Cytoprotect December 1997
NCT00003554 Completed Phase 2 Rituximab in Treating Patients With Multiple Myeloma November 1998 April 2004
NCT00003631 Completed Phase 2 Chemotherapy Plus Radiation Therapy in Treating Patients With Refractory or Relapsed Hodgkin's Lymphoma August 1998
NCT00003632 Completed Phase 2 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Central Nervous System Lymphoma September 1998
NCT00003661 Completed Phase 2 Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer June 1998 March 2006
NCT00003662 Completed Phase 2 Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases August 1998 January 2001
NCT00003727 Completed Phase 2 Chemotherapy and Peripheral Stem Cell Transplantation Followed by Immunotherapy in Treating Patients With Chronic Myelogenous Leukemia March 1999 February 2008
NCT00003789 Completed Phase 3 Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Locally Advanced Melanoma of the Arm or Leg March 1999
NCT00003816 Completed Phase 2/Phase 3 Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic Cancer October 19, 1998 July 12, 2019
NCT00003899 Completed Phase 1 Chemotherapy Plus Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors January 1999 November 2001
NCT00003954 Completed Phase 1/Phase 2 Melphalan and Stem Cell Transplant Before Total-Body Irradiation and Donor Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma March 1999
NCT00003957 Completed Phase 2 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Non-Hodgkin's Lymphoma December 1998 August 2001
NCT00003972 Completed Phase 3 Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Stage II or Stage IIIA Breast Cancer July 1998 March 2003
NCT00004056 Completed Phase 1 Combination Chemotherapy Followed by Melphalan and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Acute Myeloid Leukemia October 1999 March 2007
NCT00004088 Completed Phase 2 Combination Chemo, Peripheral Stem Cell Transplant, Biological Therapy, Pamidronate and Thalidomide for Multiple Myeloma April 13, 1999 January 9, 2018
NCT00004158 Completed Phase 1/Phase 2 Radiation Therapy Using Holmium Ho 166 DOTMP Plus Melphalan and Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma June 1999 January 2006
NCT00556127 Completed Phase 2 Rituximab in Addition to Chemotherapy With Autologous Stem Cell Transplantation as Treatment Diffuse Large B-Cell Lymphoma June 2002 September 2006
NCT00564200 Completed Phase 2 MINIALO-VELCADE2005: A Study of Bortezomib (Velcade) Treated Multiple Myeloma Patients Pre and Post Allogeneic Haematopoietic Progenitor Cell Transplant With no Myeloablative Conditioning November 2007 October 2014
NCT00565968 Completed Phase 1 Sorafenib and Isolated Limb Infusion of Melphalan in Treating Patients With Stage III Melanoma of the Arm or Leg October 2007
NCT00566098 Completed Phase 1/Phase 2 Activated White Blood Cells With ASCT for Newly Diagnosed Multiple Myeloma November 2007 October 2018
NCT00567567 Completed Phase 3 Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma November 5, 2007 March 31, 2022
NCT00574496 Completed Phase 2 Combination Chemotherapy Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or High-Risk Primary Refractory Hodgkin Lymphoma November 13, 2007 August 2, 2022
NCT00577096 Completed N/A Effects of Exercise in Combination With Epoetin Alfa October 2001 June 2004
NCT00577278 Completed Phase 2 A Phase II Study of Allo-HCT for B-Cell NHL Using Zevalin, Fludarabine and Melphalan October 3, 2007 December 14, 2023
NCT00589563 Completed Phase 2 Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer May 2007 February 2012
NCT00591630 Completed Phase 2 Zevalin/BEAM/Rituximab vs BEAM/Rituximab With or Without Rituximab in Autologous Stem Cell Transplantation November 14, 2007 March 5, 2020
NCT00602706 Completed Phase 1/Phase 2 Samarium Sm 153 Lexidronam Pentasodium and High-Dose Melphalan in Treating Patients With Multiple Myeloma Undergoing Stem Cell Transplant January 2000 July 2010
NCT00621400 Completed Phase 1/Phase 2 Lenalidomide in Combination With Melphalan and Dexamethasone in Newly-diagnosed Light-chain (AL)-Amyloidosis January 2008 December 2009
NCT00641030 Completed Phase 1 Clofarabine and High-Dose Melphalan Followed by Donor Stem Cell Transplant in Patients With Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Myelodysplastic Syndromes July 2007 January 2011
NCT00651937 Completed Phase 2 Trial of Two Stem Cell Doses To Reduce Transplant Induced Symptom Burden March 2008 January 2016
NCT00661544 Completed Phase 1/Phase 2 Arsenic Trioxide With Ascorbic Acid and Melphalan for Myeloma Patients March 2004 June 2007
NCT00679367 Completed Phase 2 Melphalan, Lenalidomide, and Dexamethasone in Treating Patients With Primary Systemic Amyloidosis May 2008 May 2015
NCT00683046 Completed Phase 2 T-Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Hematologic Malignancies November 2001 December 2014
NCT00691015 Completed Phase 2 Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplant May 2008 April 2014
NCT00695409 Completed Phase 2 Yttrium-90 Ibritumomab Tiuxetan Plus High-Dose BEAM Followed By ASCT For Relapsed B-Cell Non-Hodgkin Lymphoma March 18, 2008 March 27, 2017
NCT00734149 Completed Phase 2 Bortezomib With Melphalan and Prednisone for Multiple Myeloma July 2004 February 2008
NCT00743288 Completed Phase 1/Phase 2 Melphalan and Panobinostat (LBH589) for the Treatment of Patients With Recurrent Multiple Myeloma July 2008 December 2012
NCT00784823 Completed Phase 1/Phase 2 Study Combining Bortezomib With High Dose Melphalan to Treat Multiple Myeloma January 2007 December 2013
NCT00789256 Completed N/A Low Dose Melphalan and Bortezomib for AML and High-Risk MDS September 2004 December 2008
NCT00790647 Completed Phase 2 Melphalan, Bortezomib, and Stem Cell Transplant in Treating Patients With Primary Systemic Amyloidosis June 2008 November 2014
NCT00792142 Completed Phase 2 Bortezomib, Thalidomide, and Dexamethasone After Melphalan and Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma January 16, 2008 April 21, 2014
NCT00793572 Completed Phase 2 Autologous or Syngeneic Stem Cell Transplant Followed by Donor Stem Cell Transplant and Bortezomib in Treating Patients With Newly Diagnosed High-Risk, Relapsed, or Refractory Multiple Myeloma October 2008 October 2016
NCT00793845 Completed Phase 2 Tandem High-dose Chemotherapy and Autologous Stem Cell Rescue in Patients With High-risk Neuroblastoma August 2008 January 2018
NCT00824135 Completed Phase 1 Haploidentical Hematopoietic Stem Cell Transplantation Using A Novel Clofarabine Containing Conditioning Regimen For Patients With Refractory Hematologic Malignancies January 2009 December 2016
NCT00840684 Completed Phase 1/Phase 2 Laromustine, Daunorubicin, and Cytarabine in Treating Patients With Acute Myeloid Leukemia January 2009
NCT00856388 Completed N/A Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders January 14, 2009 March 13, 2019
NCT00890500 Completed Phase 1 Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies. January 2011 October 2013
NCT00890552 Completed N/A A Pilot Study of Lenalidomide, Melphalan and Dexamethasone in AL Amyloidosis April 2009 October 2012
NCT00899847 Completed Phase 2 Phase 2 Study of Autologous Followed by Nonmyeloablative Allogeneic Transplantation Using TLI & ATG May 2009 December 2014
NCT00911859 Completed Phase 2 A Study to Compare CNTO 328 (Anti-IL-6 Monoclonal Antibody) and VELCADE-Melphalan-Prednisone (VMP) With VMP Alone in Previously Untreated Multiple Myeloma Patients June 2009 April 2013
NCT00916058 Completed Phase 1/Phase 2 Conditioning Regimen of Bendamustine and Melphalan Followed by Transplant in Patients With Multiple Myeloma April 23, 2009 March 1, 2018
NCT00936936 Completed Phase 2 High-dose Chemotherapy for Poor-Prognosis Relapsed Germ-Cell Tumors June 2, 2009 January 11, 2024
NCT00943592 Completed Phase 1/Phase 2 Clofarabine-Melphalan-Alemtuzumab Conditioning in Patients With Advanced Hematologic Malignancies March 2006 November 2013
NCT00948922 Completed Phase 2 Melphalan+Bortezomib as a Conditioning Regimen for Autologous and Allogeneic Stem Cell Transplants in Multiple Myeloma June 18, 2009 May 14, 2019
NCT00968760 Completed Phase 1 CD19-specific T Cell Infusion in Patients With B-Lineage Lymphoid Malignancies June 20, 2011 April 23, 2020
NCT00985959 Completed Phase 1 A Study of JNJ-26866138 (Bortezomib) in Untreated Multiple Myeloma Patients Who Are Not Candidates for Hematopoietic Stem Cell Transplant (HSCT) July 2008 June 2010
NCT00992446 Completed Phase 2 Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma September 2, 2010 October 29, 2019
NCT01008462 Completed Phase 2 Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia March 18, 2010 June 30, 2018
NCT01010217 Completed Phase 2 Mismatched Transplantation Using High-dose Post-transplant Cyclophosphamide November 5, 2009 October 5, 2017
NCT01035463 Completed Phase 1/Phase 2 Lenalidomide Therapy After Chemotherapy & Stem Cell Transplant in Treating Chemotherapy Resistan Non-Hodgkin Lymphoma November 12, 2009 July 27, 2018
NCT01039025 Completed Phase 2 TMC (Topotecan, Cyclophosphamide and Melphalan) for Multiple Myeloma February 18, 2002 May 19, 2006
NCT01045460 Completed Phase 2 Trial of Activated Marrow Infiltrating Lymphocytes Alone or in Conjunction With an Allogeneic Granulocyte Macrophage Colony-stimulating Factor (GM-CSF)-Based Myeloma Cellular Vaccine in the Autologous Transplant Setting in Multiple Myeloma January 15, 2010 June 2020
NCT01078454 Completed Phase 3 Melphalan and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Systemic Light-Chain Amyloidosis November 2010 November 27, 2012
NCT01079936 Completed Phase 1/Phase 2 Lenalidomide and High-Dose Melphalan March 2010 March 2015
NCT01083316 Completed Phase 2 Bortezomib and Dexamethasone Followed by High-Dose Melphalan and Stem Cell Transplantation for Primary (AL) Amyloidosis September 2009 September 4, 2020
NCT01119066 Completed Phase 2 HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies May 3, 2010 March 30, 2021
NCT01141712 Completed Phase 2 Autologous Transplant in HIV Patients (BMT CTN 0803) April 2010 June 2016
NCT01200329 Completed Phase 2 High-Dose Gemcitabine, Busulfan and Melphalan for Patients With Refactory Hodgkin's Disease June 2011 December 6, 2018
NCT01237249 Completed Phase 2 Study of Treatment for Newly Diagnosed Multiple Myeloma Patients Older Than 65 Years With Sequential Melphalan/Prednisone/Velcade (MPV) Followed by Revlimid/Low Dose Dexamethasone (Rd) Versus Alternating Velcade/Melphalan/Prednisone (MPV) With Revlimid/Low Dose Dexamethasone February 2011 May 2016
NCT01237951 Completed Phase 2 High-Dose Gemcitabine, Busulfan and Melphalan With Hematopoietic-Cell Support for Patients With Poor-Risk Myeloma November 8, 2010 September 20, 2017
NCT01256398 Completed Phase 2 Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia December 14, 2010 November 15, 2021
NCT01279694 Completed Phase 1/Phase 2 Trial of Carfilzomib Plus Melphalan and Prednisone in Elderly Untreated Patients With Multiple Myeloma (CARMYSAP) October 2010 February 2014
NCT01335685 Completed Phase 1/Phase 2 Study of Oral Ixazomib in Combination With Melphalan and Prednisone in Participants With Newly Diagnosed Multiple Myeloma June 27, 2011 December 29, 2016
NCT01341262 Completed Phase 2 THAL-DEX Incorporated Into Double PBSC Autotransplantation for Untreated Multiple Myeloma (MM) March 2002 January 2009
NCT01408563 Completed Phase 2 Reduced Intensity Double Umbilical Cord Blood Transplantation December 2011 June 2017
NCT01413178 Completed Phase 3 A Randomized Trial to Compare Busulfan + Melphalan 140 mg/m2 With Melphalan 200 mg/m2 as Preparative Regimen for Autologous Hematopoietic Stem Cell Transplantation for Multiple Myeloma September 30, 2011 March 10, 2019
NCT01421173 Completed Phase 1 Vorinostat With Gemcitabine, Busulfan, and Melphalan With Stem Cell Transplant (SCT) in Relapsed or Refractory Lymphoid Malignancies August 2011 September 2015
NCT01471067 Completed Phase 1 Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies July 13, 2012 April 25, 2017
NCT01505569 Completed N/A Auto Transplant for High Risk or Relapsed Solid or CNS Tumors October 20, 2011 February 1, 2024
NCT01526603 Completed N/A High Dose Chemotherapy and Autologous Transplant for Neuroblastoma March 28, 2012 May 30, 2023
NCT01529827 Completed Phase 2 Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies February 28, 2012 August 29, 2019
NCT01538472 Completed Phase 1/Phase 2 Y Zevalin and BEAM in Autologous Stem Cell Transplantation (ASCT) for Lymphoma September 2003 November 2011
NCT01605032 Completed Phase 2 Busulfan, Melphalan, and Bortezomib Before First-Line Stem Cell Transplant in Treating Patients With Multiple Myeloma February 2012 March 2018
NCT01625351 Completed Phase 1 A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas August 20, 2012 February 10, 2020
NCT01626092 Completed N/A Reduced-Intensity Hematopoietic Stem Cell Transplant for High Risk Lysosomal and Peroxisomal Disorders July 11, 2012 November 2013
NCT01690143 Completed Phase 1/Phase 2 Carfilzomib + High Dose Melphalan as Preparative Regimen for Autologous Hematopoietic Stem Cell Transplantation May 2012 November 1, 2017
NCT01702831 Completed Phase 2 Busulfan & Melphalan Conditioning for Autologous Stem Cell Transplant (ASCT) and Lenalidomide Maintenance October 1, 2013 July 31, 2022
NCT01702961 Completed N/A Rituxan + BEAM and Auto Stem Cell Transplant for High Risk Lymphoma or Hodgkin's Disease June 2002 January 2017
NCT01731886 Completed Phase 4 Lenalidomide and Dexamethasone With/Without Stem Cell Transplant in Patients With Multiple Myeloma September 2012 April 11, 2017
NCT01807611 Completed Phase 2 Haploidentical Donor Hematopoietic Progenitor Cell and NK Cell Transplantation for Hematologic Malignancy May 16, 2013 September 27, 2021
NCT01818752 Completed Phase 3 Phase 3 Study of Carfilzomib, Melphalan, Prednisone vs Bortezomib, Melphalan, Prednisone in Newly Diagnosed Multiple Myeloma July 8, 2013 November 4, 2016
NCT01824693 Completed Phase 2 Busulfan, Cyclophosphamide, and Melphalan or Busulfan and Fludarabine Phosphate Before Donor Hematopoietic Cell Transplant in Treating Younger Patients With Juvenile Myelomonocytic Leukemia June 24, 2013 December 31, 2017
NCT01842308 Completed Phase 1/Phase 2 Carfilzomib and Melphalan Before Stem Cell Transplant in Treating Patients With Multiple Myeloma June 4, 2013 October 28, 2019
NCT01849783 Completed Phase 2 Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma April 4, 2013 September 30, 2020
NCT01877837 Completed Phase 3 Stem Cell Transplantation for Sickle Cell Anemia June 2011 September 2021
NCT01904136 Completed Phase 1/Phase 2 Natural Killer Cells Before and After Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia April 22, 2014 February 28, 2022
NCT01916252 Completed Phase 3 Bortezomib (Velcade®), Lenalidomide (Revlimid®) and IV Busulfan (Busilvex®) in Patients Under 65 Years Old September 2013 November 16, 2016
NCT01921387 Completed Phase 1/Phase 2 Radiolabeled Monoclonal Antibody and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With High-Risk Lymphoid Malignancies October 9, 2013 July 26, 2020
NCT01936090 Completed Phase 1 Bortezomib, Melphalan, and Total-Body Irradiation Before Stem Cell Transplant in Treating Patients With Multiple Myeloma August 2013 February 16, 2018
NCT01983969 Completed Phase 1/Phase 2 Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma November 7, 2013 November 22, 2017
NCT01998503 Completed Phase 3 Bortezomib and Dexamethasone Followed by ASCT Compared With ASCT Alone in Treating Patients With AL Amyloidosis December 2007 August 2013
NCT01998971 Completed Phase 1 A Study of JNJ-54767414 (HuMax CD38) (Anti-CD38 Monoclonal Antibody) in Combination With Backbone Treatments for the Treatment of Patients With Multiple Myeloma February 18, 2014 January 11, 2024
NCT02007863 Completed N/A Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and Myelodysplasia August 2008 June 2014
NCT02043847 Completed Phase 1 Total Marrow Irradiation With High Dose Melphalan Prior to Autologous Transplant for Relapsed or Refractory Multiple Myeloma (BMT-03) January 14, 2014 September 14, 2016
NCT02059239 Completed Phase 1/Phase 2 Bendamustine Bridge to Autologous or Allogeneic Transplant for Relapsed/Refractory Lymphoma June 4, 2014 June 15, 2020
NCT02072863 Completed Phase 1/Phase 2 A Study of Oprozomib, Melphalan, and Prednisone in Transplant Ineligible Patients With Newly Diagnosed Multiple Myeloma January 2014 September 2015
NCT02097134 Completed Phase 1 Intra-arterial Melphalan in Treating Younger Patients With Unilateral Retinoblastoma October 31, 2014 September 30, 2023
NCT02130869 Completed Phase 1 A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas October 10, 2014 December 20, 2017
NCT02197221 Completed Phase 3 Bortezomib-Melphalan Conditioning Regimen vs Melphalan for Frontline Transplant Eligible Patients With Multiple Myeloma January 2015 December 31, 2018
NCT02206425 Completed Phase 1/Phase 2 Ixazomib as a Replacement for Carfilzomib and Bortezomib for Multiple Myeloma Patients September 2014 March 6, 2018
NCT02331368 Completed Phase 2 Phase 2 Multi-center Study of Anti-PD-1 During Lymphopenic State After HDT/ASCT for Multiple Myeloma June 2015 June 2017
NCT02390544 Completed Phase 1 A Pharmacokinetic Study of Melphalan in Children May 8, 2015 September 23, 2018
NCT02435901 Completed Phase 1/Phase 2 HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity December 2008 December 2019
NCT02440464 Completed Phase 2 Allogeneic Hematopoietic Stem Cell Transplantation With Ixazomib for High Risk Multiple Myeloma (BMT CTN 1302) August 2015 October 1, 2020
NCT02472392 Completed Phase 1 Study To Examine Toxicity Of Allogeneic Stem Cell Transplantation For Relapsed Or Therapy Refractory Ewings Sarcoma April 2013 December 2016
NCT02474563 Completed Observational Study to Evaluate the Efficacy and Safety of Bortezomib, Melphalan, Prednisone (VMP) in Participants With Multiple Myeloma May 2011 May 2014
NCT00001296 Completed Phase 3 A Randomized Phase III Trial of Hyperthermic Isolated Limb Perfusion With Melphalan, Tumor Necrosis Factor, and Interferon-Gamma in Patients With Locally Advanced Extremity Melanoma February 1992 October 2000
NCT02504359 Completed Phase 1 Combination Chemotherapy and Donor Stem Cell Transplant Followed by Ixazomib Citrate Maintenance Therapy in Treating Patients With Relapsed High-Risk Multiple Myeloma July 20, 2015 September 9, 2020
NCT02506959 Completed Phase 2 Panobinostat, Gemcitabine Hydrochloride, Busulfan, and Melphalan Before Stem Cell Transplant in Treating Patients With Refractory or Relapsed Multiple Myeloma September 14, 2015 June 3, 2024
NCT02581007 Completed Phase 2 Reduced Intensity Conditioning Transplant Using Haploidentical Donors October 26, 2015 December 28, 2020
NCT02660281 Completed Phase 1 URMC Related Haplo-identical Donor BMT October 2015 January 7, 2021
NCT02707393 Completed Phase 2/Phase 3 Allogeneic Stem Cell Transplantation for Children With CML April 30, 2009 December 1, 2020
NCT02728102 Completed Phase 2 Dendritic Cell/Myeloma Fusion Vaccine for Multiple Myeloma (BMT CTN 1401) July 2016 December 9, 2022
NCT02756572 Completed Phase 2 Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms September 22, 2016 July 1, 2020
NCT02766465 Completed Phase 2 Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503) November 2016 May 2, 2023
NCT02771197 Completed Phase 2 Lymphodepletion and Anti-PD-1 Blockade to Reduce Relapse in AML Patient Not Eligible for Transplant September 28, 2016 July 31, 2023
NCT02780609 Completed Phase 1/Phase 2 Selinexor Plus High-Dose Melphalan (HDM) Before Autologous Hematopoietic Cell Transplantation for Multiple Myeloma July 20, 2017 February 23, 2021
NCT02867800 Completed Phase 1 Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease July 2016 December 30, 2023
NCT02880293 Completed N/A Haploidentical (Half-matched) Related Donor Stem Cell Transplantation Using Killer Immunoglobulin-like Receptors in Addition to Normal Selection Factors to Determine the Best Donor August 23, 2016 November 20, 2023
NCT02917096 Completed Phase 1 Ruxolitinib Phosphate and Chemotherapy Given Before and After Reduced Intensity Donor Stem Cell Transplant in Treating Patients With Myelofibrosis November 13, 2016 August 31, 2023
NCT02960646 Completed Phase 1 Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies January 18, 2017 February 13, 2023
NCT03019640 Completed Phase 2 Umbilical Cord Blood NK Cells, Rituximab, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma October 10, 2017 August 16, 2021
NCT03072771 Completed Phase 1 Blinatumomab Consolidation Post Autologous Stem Cell Transplantation in Patients With Diffuse Large B-Cell Lymphoma (DLBCL) August 1, 2017 October 30, 2023
NCT03096782 Completed Phase 2 Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma October 13, 2017 September 20, 2022
NCT03187223 Completed Phase 2 Bendamustine and Melphalan in Myeloma July 20, 2017 May 28, 2020
NCT03217812 Completed Phase 3 A Study of VELCADE (Bortezomib) Melphalan-Prednisone (VMP) Compared to Daratumumab in Combination With VMP (D-VMP), in Participants With Previously Untreated Multiple Myeloma Who Are Ineligible for High-Dose Therapy (Asia Pacific Region) November 23, 2017 March 8, 2024
NCT03393611 Completed Phase 1 CPX-351 Salvage Therapy Followed by Haplo-Cord Transplant for Relapsed/Refractory Leukemia or Myelodysplastic Syndrome November 30, 2012 November 18, 2021
NCT03412565 Completed Phase 2 A Study to Evaluate Subcutaneous Daratumumab in Combination With Standard Multiple Myeloma Treatment Regimens April 26, 2018 April 18, 2024
NCT03426969 Completed Early Phase 1 Combination Chemotherapy, Total Body Irradiation, and Donor Blood Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis January 31, 2018 September 21, 2020
NCT03609827 Completed Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients September 1, 2015 May 31, 2021
NCT03792815 Completed Phase 2 Busulfan, Melphalan and Etoposide as Conditioning for Autologous Transplantation for Non-Hodgkin's Lymphoma (NHL) October 2009 September 2013
NCT03794167 Completed Phase 2 BuCE Versus BuME as Conditioning Therapy in Non-Hodgkin's Lymphoma June 1, 2012 November 30, 2018
NCT04682405 Completed Phase 2 Uproleselan (GMI-1271) for GI Toxicity Prophylaxis During Melphalan-Conditioned Autologous Hematopoietic Cell Transplantation (Auto-HCT) for Multiple Myeloma (MM) May 5, 2021 November 11, 2022
NCT01728051 No longer available Expanded Access Study of Melphalan With Delcath CS-PHP System in Patients With Ocular/Cutaneous Melanoma Mets to Liver
NCT00799539 No longer available A Study to Further Assess Safety and Effectiveness Data of the Bortezomib(Velcade)/Melphalan/Prednisone (BMP) Regimen in Previously Untreated and Transplant Ineligible Multiple Myeloma Patients
NCT06022939 Not yet recruiting Phase 3 Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis July 1, 2024 October 29, 2030
NCT06207799 Not yet recruiting Phase 2 Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma July 30, 2024 December 31, 2031
NCT05303727 Not yet recruiting Phase 2 Allogeneic Hematopoietic Stem Cell Transplantation for 4/M Neuroblastoma August 2022 August 2027
NCT06377540 Not yet recruiting Phase 2 MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma August 1, 2024 September 1, 2027
NCT06287944 Not yet recruiting Phase 1 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome June 18, 2024 February 24, 2027
NCT05903937 Not yet recruiting Phase 1 Locoregional Administration of TIL and Lymphodepletion in Patients With Melanoma and Liver Metastases December 31, 2023 December 31, 2029
NCT05565105 Not yet recruiting Phase 2 CD34+ Transplants for Leukemia and Lymphoma June 2024 June 2031
NCT05863845 Not yet recruiting N/A Efficacy and Safety of Venetoclax Combined With BEAM Pretreatment in Autologous Transplantation for DLBCL June 1, 2023 November 30, 2025
NCT05139004 Recruiting Phase 1 90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrome July 19, 2022 December 13, 2024
NCT02605421 Recruiting Phase 2 Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma June 2016 July 2025
NCT04370301 Recruiting Phase 2 Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis February 9, 2021 August 31, 2029
NCT06195891 Recruiting Phase 1 Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome September 28, 2024 June 21, 2027
NCT03016806 Recruiting Phase 1 Umbilical Cord Blood Transplantation From Unrelated Donors June 2015 June 2026
NCT03602235 Recruiting Phase 1 High Dose Ascorbic Acid for Plasma Cell Disorders March 5, 2019 August 31, 2026
NCT05735717 Recruiting Phase 2 MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies May 11, 2023 November 30, 2030
NCT04384692 Recruiting Phase 2 Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis December 18, 2020 December 31, 2029
NCT00692939 Recruiting Phase 1/Phase 2 Autologous Stem Cell Transplantation for Crohn's Disease June 26, 2012 December 2026
NCT02727803 Recruiting Phase 2 Personalized NK Cell Therapy in CBT May 19, 2016 May 31, 2025
NCT05436418 Recruiting Phase 1/Phase 2 The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation November 18, 2022 July 2, 2027
NCT01962415 Recruiting Phase 2 Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT February 4, 2014 November 2024
NCT05457556 Recruiting Phase 3 Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome March 15, 2023 December 1, 2027
NCT05466318 Recruiting Phase 3 ChiCGB vs BEAM in High-risk or R/R Lymphomas July 1, 2022 December 30, 2025
NCT05504291 Recruiting Phase 2 A Study to Give Treatment Inside the Eye to Treat Retinoblastoma November 4, 2022 December 31, 2026
NCT03579875 Recruiting Phase 2 Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders November 13, 2018 January 5, 2029
NCT05508009 Recruiting Phase 1/Phase 2 Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor January 10, 2023 October 2034
NCT03570983 Recruiting Phase 2 A Trial Comparing Single Agent Melphalan to Carmustine, Etoposide, Cytarabine, and Melphalan (BEAM) as a Preparative Regimen for Patients With Multiple Myeloma Undergoing High Dose Therapy Followed by Autologous Stem Cell Reinfusion September 5, 2018 December 2024
NCT05636787 Recruiting Phase 2 Clinical Trial Investigating the Chemotherapeutic Compound Treosulfan (Trecondi® Ideogen) in Myeloma Patients June 6, 2023 April 2028
NCT04018937 Recruiting Phase 2 Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation March 22, 2019 January 2027
NCT02790515 Recruiting Phase 2 Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation July 14, 2016 July 1, 2025
NCT04098393 Recruiting Phase 1 Giving Chemotherapy for a Shortened Amount of Time Before a Stem Cell Transplantation September 18, 2019 September 2025
NCT03494569 Recruiting Phase 1 Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome July 6, 2018 November 11, 2028
NCT06172296 Recruiting Phase 3 Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma April 19, 2024 December 31, 2029
NCT01804634 Recruiting Phase 2 Reduced Intensity Haploidentical BMT for High Risk Solid Tumors March 27, 2013 January 2030
NCT04483206 Recruiting Phase 1 Personalized Autologous Transplant for Multiple Myeloma May 20, 2021 December 31, 2026
NCT04221035 Recruiting Phase 3 High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN) November 5, 2019 November 2032
NCT06158828 Recruiting Phase 1/Phase 2 Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML May 15, 2024 May 31, 2030
NCT04530487 Recruiting Phase 2 Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults August 19, 2020 May 9, 2025
NCT06140966 Recruiting Phase 2 Study to Evaluate the Safety and Efficacy of Daratumumab and Carfilzomib-based Induction/Consolidation/Maintenance Therapy in Transplant-eligible, Ultra High-risk, Newly Diagnosed Multiple Myeloma October 20, 2023 October 20, 2027
NCT06028828 Recruiting Phase 2 Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation September 11, 2023 September 2027
NCT04232085 Recruiting Phase 2 Reduced Intensity BMT for Immune Dysregulatory and Bone Marrow Failure Syndromes Using Post-Transplant Cyclophosphamide February 12, 2020 December 31, 2026
NCT01652092 Recruiting N/A Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies September 4, 2012 December 2026
NCT04799002 Recruiting Phase 3 Topotecan and Melphalan for Retinoblastoma March 11, 2021 December 30, 2027
NCT03856216 Recruiting Phase 2 Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation October 28, 2019 March 31, 2025
NCT04812470 Recruiting Phase 1 Hepatic Arterial Infusion of Autologous Tumor Infiltrating Lymphocytes in Patients With Melanoma and Liver Metastases February 6, 2023 February 2030
NCT03852407 Recruiting Phase 2 Allogeneic Hematopoietic Cell Transplantation From HLA-matched Donor After Flu-Mel-PTCy Versus Flu-Mel-ATG Reduced-intensity Conditioning February 4, 2019 November 1, 2038
NCT04150042 Recruiting Phase 1 SHARON: A Clinical Trial for Metastatic Cancer With a BRCA or PALB2 Mutation Using Chemotherapy and Patients' Own Stem Cells January 13, 2021 December 2025
NCT03829371 Recruiting Phase 4 STUDY COMPARING TWO STANDARD TREATMENTS IN AUTOLOGOUS STEM CELL TRANSPLANTATION INELIGIBLE POPULATION AFFECTED BY MULTIPLE MYELOMA January 3, 2019 January 3, 2030
NCT03125642 Recruiting Phase 2 Auto Stem Cell Transplant for Lymphoma Patients April 20, 2017 April 30, 2026
NCT02333162 Recruiting Phase 1 Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant December 5, 2014 December 1, 2028
NCT03118492 Recruiting Phase 1 Combination Chemotherapy, Total Body Irradiation, and Donor Blood Stem Cell Transplant in Treating Patients With Secondary Myelofibrosis May 24, 2017 March 24, 2025
NCT00357565 Recruiting Phase 2 Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia November 2005 December 2025
NCT06001385 Recruiting Phase 2 HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis December 8, 2023 June 30, 2026
NCT04937634 Recruiting Phase 1 Pharmacokinetic Study of Melphalan in Pediatric Hematopoietic Stem Cell Transplantation September 11, 2020 September 2023
NCT04982354 Recruiting Phase 1/Phase 2 Induction Therapy for Patients With FLT3 Mutated Acute Myeloid Leukemia July 5, 2022 August 1, 2032
NCT04994977 Recruiting Phase 1 Intra-Arterial Chemotherapy for Newly Diagnosed, Residual, or Recurrent Atypical Choroid Plexus Papilloma and Choroid Plexus Carcinoma Prior to Second-Look Surgery May 4, 2023 December 2026
NCT03736616 Recruiting Phase 2 Acalabrutinib Plus RICE for Relapsed/Refractory DLBCL August 16, 2019 September 2023
NCT04022239 Recruiting Phase 1/Phase 2 Bendamustine With or Without Cyclophosphamide in Preventing GVHD in Patients Undergoing Stem Cell Transplant March 13, 2020 July 31, 2025
NCT05031897 Recruiting Phase 2 Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Undergo a Hematopoietic Stem Cell Transplant October 25, 2021 October 1, 2024
NCT05088356 Recruiting Phase 1 Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft September 7, 2021 December 2025
NCT05115630 Recruiting Phase 1/Phase 2 Off-the-shelf NK Cells + SCT for Myeloid Malignancies April 8, 2022 June 1, 2024
NCT03073694 Recruiting Phase 2 Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis July 14, 2017 July 2025
NCT04904588 Recruiting Phase 2 HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide September 30, 2021 July 2024
NCT04903678 Recruiting N/A Intrathecal Chemotherapy for Central Nervous System Metastasis in Retinoblastoma May 1, 2021 May 1, 2030
NCT01704716 Recruiting Phase 3 High Risk Neuroblastoma Study 1.8 of SIOP-Europe (SIOPEN) February 2002 September 2026
NCT05617625 Suspended Phase 2 CD34+ Enriched Transplants to Treat Myelodysplastic Syndrome June 2024 June 2031
NCT01653418 Terminated Phase 2 Phase II Study of V-BEAM Conditioning Regimen Prior to Second Autologous Stem Cell Transplantation September 2012 December 2013
NCT01659658 Terminated Phase 3 Study of Dexamethasone Plus IXAZOMIB (MLN9708) or Physicians Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis December 26, 2012 July 11, 2022
NCT04205240 Terminated Phase 2 Reduce Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed Multiple Myeloma December 22, 2020 November 22, 2021
NCT01745913 Terminated Phase 2 Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies October 26, 2012 April 29, 2015
NCT01746173 Terminated Phase 2 CHOEP + High Dose Therapy + Auto SCT for T-Cell Lymphoma July 2013 October 2014
NCT00301860 Terminated N/A Donor Stem Cell Transplant Followed By Donor White Blood Cell Infusions in Treating Young Patients With Hematologic Cancer January 2003 November 2007
NCT01794572 Terminated Phase 1/Phase 2 Phase 1-2 Study of Total Bone Marrow Irradiation With Helicoidal Tomotherapy in 1st Myeloma Relapse April 24, 2013 January 7, 2020
NCT00290628 Terminated N/A Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer October 1999 April 2007
NCT01807286 Terminated Phase 1 Pomalidomide With Melphalan and Dexamethasone for Untreated Systemic AL Amyloidosis January 2014 February 2016
NCT00281879 Terminated Phase 2 Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer February 2006 March 2008
NCT00253721 Terminated Phase 1 Melphalan With BBBD in Treating Patients With Brain Malignancies May 1998 December 2016
NCT01875237 Terminated Phase 1/Phase 2 Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene December 27, 2013 March 7, 2017
NCT00003086 Terminated Phase 1/Phase 2 Repeated Bone Marrow Transplantation in Treating Women With Advanced Breast Cancer March 1997 January 28, 2001
NCT01907009 Terminated Phase 2/Phase 3 A Phase II Study Evaluating Intravenous Melphalan With Autologous Whole Blood Stem Cell Transplantation Over Three Cycles In Patients With Castration-Resistant Prostate Cancer (MEL-CAP) January 2013 December 22, 2016
NCT04412707 Terminated Phase 2 A PK, Safety and Tolerability Study of Peripheral and Central Infusion of Melflufen in RRMM Patients August 4, 2020 January 10, 2022
NCT04455139 Terminated Phase 2 A Prospective International Multicenter Clinical Trial for Eyes With Relapsed Retinoblastoma November 15, 2021 May 22, 2023
NCT02043860 Terminated Phase 1 Total Marrow Irradiation With High Dose Melphalan Prior to Autologous Transplant for Multiple Myeloma January 10, 2014 November 7, 2016
NCT00176839 Terminated Phase 2/Phase 3 Stem Cell Transplantation for Hematological Malignancies June 7, 2000 February 2012
NCT02116959 Terminated Phase 1 Alternating Systemic Chemotherapy and Intra-Arterial Melphalan (IAM) Chemotherapy in Children With Intra-Ocular Retinoblastoma July 23, 2014 May 25, 2019
NCT00121186 Terminated Phase 2 S0501 Fludarabine, Melphalan, and Donor Stem Cell Transplant Followed By Tacrolimus and Methotrexate in Treating Patients for Relapsed Lymphoma July 2005 December 2011
NCT02199041 Terminated Phase 2 Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen July 11, 2014 May 23, 2017
NCT02259348 Terminated Phase 2 Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation October 2014 March 2016
NCT02295722 Terminated Phase 1/Phase 2 GEMHDM2014 : Gem-HDM HDT and ASCT for Relapsed/ Refractory Lymphoma April 2015 January 2023
NCT02310997 Terminated Phase 2 Myloablative Cord Blood Transplant in Haematological Malignancies (MAC UCBT) July 2011 May 2015
NCT02353572 Terminated Phase 1/Phase 2 Melphalan and Bortezomib Prior to Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma November 2009 September 2011
NCT02366663 Terminated Phase 3 BEAM vs. 90-Yttrium Ibritumomab Tiuxetan (Zevalin®)/BEAM With ASCT for Relapsed DLBCL January 2015 October 2016
NCT02415036 Terminated Phase 2 Melphalan for Use With the Hepatic Delivery System Treatment in Patients With Unresectable Hepatocellular Carcinoma or Intra Hepatic Cholangiocarcinoma June 2014 December 2018
NCT00075608 Terminated Phase 2 2nd Autologous Stem Cell Transplant in Patients With Persistent/Recurrent (AL) Amyloidosis August 2001 October 2011
NCT02483000 Terminated Phase 1 Anti-CD20 Radioimmunotherapy Before Chemotherapy and Stem Cell Transplant in Treating Patients With High-Risk B-Cell Malignancies February 1, 2017 September 2, 2020
NCT02489500 Terminated Phase 3 Trial of High Dose Melphalan/Stem Cell Transplant With or Without Bortezomib June 2015 April 28, 2017
NCT02589145 Terminated Phase 1/Phase 2 Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype June 22, 2016 April 8, 2019
NCT02614560 Terminated Phase 1/Phase 2 A Study of Vadastuximab Talirine Given Prior to or After Allogeneic Hematopoietic Stem Cell Transplant in AML Patients November 2015 September 14, 2017
NCT02653196 Terminated Early Phase 1 A Multi-Institutional Pilot Study of Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Malignant Neuro-Epithelial and Other Solid Tumors September 2015 August 2017
NCT02700841 Terminated Phase 2 Enhancing Anti--Tetanus Vaccine Response After Autologous Stem Cell Transplantation January 9, 2020 December 21, 2022
NCT02716805 Terminated Phase 1 Phase 1 Study of Tremelimumab, Durvalumab, High-dose Chemotherapy, + Autologous Stem Cell Transplant December 13, 2016 February 16, 2018
NCT02750254 Terminated Phase 1 Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation June 27, 2016 October 14, 2020
NCT02773550 Terminated Phase 4 Treatment With a Scheme With Low Doses of Bortezomib / Melphalan / Prednisone (MPV) in Patients With Multiple Myeloma January 2014 July 2018
NCT00583622 Terminated Phase 2 Bevacizumab Plus Gemcitabine, Docetaxel, Melphalan, and Carboplatin in Ovarian Cancer Patients December 2007 January 2012
NCT00539500 Terminated Phase 2/Phase 3 Autologous Stem Cell Rescue With CD133+ Selected Cells in High-Risk Neuroblastoma October 2007 September 5, 2012
NCT00618540 Terminated Phase 2 Reduced Intensity Hematopoietic Cell Transplantation for Patients With Resistant Langerhans Cell Histiocytosis January 2007 May 2013
NCT00074269 Terminated Phase 2 Allogeneic Stem Cell Transplant After ATG, High-Dose Melphalan, and Fludarabine for Patients With Breast Cancer July 2003 March 2008
NCT00623077 Terminated Phase 1 MT2004-30: Tomotherapy for Solid Tumors August 2005 October 2016
NCT00635024 Terminated Phase 2 Anti-thymocyte Globulin and Melphalan in Treating Patients With Relapsed Multiple Myeloma May 2008 November 2010
NCT00637767 Terminated Phase 2 High-Dose Melphalan With or Without Radiolabeled Monoclonal Antibody in Treating Patients With Multiple Myeloma Undergoing an Autologous Stem Cell Transplant December 1, 2007 October 31, 2013
NCT00052884 Terminated Phase 1 Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation January 22, 2004 March 2011
NCT00681044 Terminated Phase 2 HD Melphalan and SCT in Patients With IGDD or LCDD October 2006 January 2016
NCT00793650 Terminated Phase 1/Phase 2 Combination High Dose Melphalan and Autologous Peripheral Blood Stem Cell (PBSC) Transplant With Bortezomib for Multiple Myeloma: A Dose and Schedule Finding Study May 2005 September 2011
NCT00800150 Terminated Phase 1 Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment November 2008 October 2010
NCT00801931 Terminated Phase 1/Phase 2 Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorders September 6, 2007 May 5, 2009
NCT00827099 Terminated Phase 2 Umbilical Cord Blood (UCB) Transplant, Fludarabine, Melphalan, and Anti-thymocyte Globulin (ATG) in Treating Patients With Hematologic Cancer June 2006 November 2009
NCT00843310 Terminated Phase 2 Combination of Revlimid, Melphalan and Dexamethasone as First Line Treatment for Multiple Myeloma November 2008 October 2011
NCT00523809 Terminated Phase 2 Allogeneic Hematopoietic Stem Cell Transplantation With Bevacizumab for Advanced Solid Tumor August 2007 October 2011
NCT00505921 Terminated Phase 2 Autologous and Allogenic Transplantation With Campath-1H for T-Cell Lymphoma March 2003 November 2009
NCT00916045 Terminated Phase 2 Pilot Study of Unrelated Cord Blood Transplantation September 2009 March 2012
NCT00920153 Terminated Phase 3 Three Different Therapy Regimens in Treating Patients With Previously Untreated Hodgkin Lymphoma May 2008 March 2016
NCT03259516 Terminated Phase 1/Phase 2 Nivolumab With Chemotherapy in Refractory MDS May 25, 2017 December 25, 2018
NCT00943293 Terminated Phase 1 Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies May 2003 January 2012
NCT01050764 Terminated Phase 1/Phase 2 Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells June 2009 June 2014
NCT00429026 Terminated Phase 2 Conditioning Regimen in Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation January 2004 March 2008
NCT01116128 Terminated Phase 2 Dasatinib in Combination With Melphalan and Prednisone to Treat Relapsed and Refractory Multiple Myeloma Patients February 2008 May 2011
NCT03615105 Terminated Phase 2 Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched Donors July 25, 2018 March 6, 2024
NCT03615144 Terminated Phase 2 TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated Donors July 23, 2018 November 13, 2020
NCT00003926 Terminated Phase 1 Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors November 1998 August 2003
NCT01350258 Terminated Phase 1/Phase 2 Bone Marrow Transplant Using a Reduced Intensity Regimen That is Given in Two Steps April 2011 August 2012
NCT01359254 Terminated Phase 2 Cord Blood Transplantation for Patients With Cancer April 2010 June 2012
NCT01393769 Terminated Phase 2 Intra-arterial Chemotherapy With Melphalan for the Treatment of Retinoblastoma (RTB) in Advanced Intraocular Stage November 2009 May 2013
NCT01453088 Terminated Phase 2 Auto Transplant High Dose Melphalan vs High Dose Melphalan+Bortezomib in Pts With Multiple Myeloma Age 65 Years or Older June 24, 2010 May 1, 2022
NCT01500161 Terminated Phase 2 Pooled Unrelated Donor Umbilical Cord Blood Transplant For Hematologic Malignancy Needing Allogeneic Stem Cell Transplant Without Related HLA-Match November 2011 November 2013
NCT01518153 Terminated Phase 2 Planned Donor Lymphocyte Infusion (DLI) After Allogeneic Stem Cell Transplantation (SCT) February 2012 August 2014
NCT01548573 Terminated Phase 2 Tandem Auto Transplantation in Myeloma Patients With <12 Months of Prior Treatment May 2012 August 2014
NCT01598025 Terminated N/A Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor May 2, 2012 October 16, 2017
NCT01617213 Terminated Phase 2 Autologous Stem Cell Transplantation and Maintenance Therapy for Multiple Myeloma April 2012
NCT01658904 Terminated Phase 1/Phase 2 Carfilzomib and Stem Cell Transplant for Plasma Cell Myeloma July 2012 April 2014
NCT00003815 Unknown status Phase 3 Chemotherapy and Radiation Therapy Plus Bone Marrow Transplantation in Treating Patients With Aggressive Non-Hodgkin's Lymphoma June 1994
NCT00003163 Unknown status Phase 2 Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma or Other B-cell Cancers September 1997
NCT00436761 Unknown status Phase 1 Busulfan, Melphalan, and Antithymocyte Globulin Followed By Umbilical Cord Blood Transplant in Treating Young Patients With Refractory or Relapsed Malignant Solid Tumors May 2004
NCT00334932 Unknown status Phase 1/Phase 2 Doxorubicin Hydrochloride Liposome, Melphalan, and Bortezomib in Treating Patients With Relapsed or Refractory Stage I, Stage II, or Stage III Multiple Myeloma February 2006
NCT00003578 Unknown status Phase 3 High Dose Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Intermediate- or High-Grade Non-Hodgkin's Lymphoma January 1993
NCT03583424 Unknown status Phase 1/Phase 2 Venetoclax, Carmustine, Etoposide, Cytarabine, and Melphalan Before Stem Cell Transplant in Treating Participants With Relapsed or Refractory Non-Hodgkin Lymphoma September 10, 2018 December 31, 2022
NCT04380376 Unknown status Phase 2 Low-doses Melphalan Inhalation in Patients With COVID-19 (CoronavIrus Disease 2019) Pneumonia April 30, 2020 October 30, 2020
NCT00417053 Unknown status Phase 3 Combination Chemotherapy in Treating Infants With Newly Diagnosed Neuroblastoma Who Are Undergoing Surgery With or Without Autologous Bone Marrow or Peripheral Stem Cell Transplant
NCT00410631 Unknown status Phase 3 Observation, Combination Chemotherapy, Radiation Therapy, and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma October 2004
NCT01920516 Unknown status Isolated Limb Perfusion of Melphalan for Melanoma and Sarcoma Treatment July 2013 July 2020
NCT04264078 Unknown status Early Phase 1 Anti-CD7 U-CAR-T Cell Therapy for T/NK Cell Hematologic Malignancies March 1, 2021 June 1, 2023
NCT00008307 Unknown status Phase 2 Combination Chemotherapy Followed by Donor Bone Marrow Transplant or Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer or Genetic Disorders April 1998
NCT00004903 Unknown status Phase 2 Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma October 1999
NCT00181025 Unknown status Phase 2 Isolated Pelvic and Limb Perfusion in the Treatment of Locally Advanced Sarcoma of Pelvis and Limbs' Girdle May 2004
NCT00526734 Unknown status Phase 2 High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Newly Diagnosed Stage I, Stage II, or Stage III Multiple Myeloma February 2006
NCT02784054 Unknown status Phase 2 Reduced Dose Radiotherapy Following High Dose Chemotherapy in Intracranial Non-germinomatous Germ Cell Tumor April 2014 March 2023
NCT00669812 Unknown status Phase 2 High-Dose Chemotherapy Given Together With Peripheral Blood Stem Cell Transplant in Treating Patients With Intestinal T-Cell Lymphoma February 2008
NCT00030719 Unknown status Phase 3 Combination Chemotherapy With or Without Filgrastim Before Surgery, High-Dose Chemotherapy, and Radiation Therapy Followed by Isotretinoin With or Without Monoclonal Antibody in Treating Patients With Neuroblastoma December 2001
NCT04264039 Unknown status Early Phase 1 Anti-CD19 U-CAR-T Cell Therapy for B Cell Hematologic Malignancies April 1, 2020 April 1, 2022
NCT00028886 Unknown status Phase 3 Combination Chemotherapy With or Without Thalidomide in Treating Patients With Multiple Myeloma March 2001
NCT02784015 Unknown status Phase 2 Response Based Treatment for Children With Unresectable Localized Soft Tissue Sarcoma May 2016 May 2023
NCT00550992 Unknown status N/A Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia January 2006
NCT00526318 Unknown status N/A Combination Chemotherapy Followed by Stem Cell Transplant and Isotretinoin in Treating Young Patients With High-Risk Neuroblastoma January 2007
NCT00720447 Unknown status Phase 2 Donor Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma November 2008
NCT00747877 Unknown status Phase 3 High-Dose Melphalan and a Second Stem Cell Transplant or Low-Dose Cyclophosphamide in Treating Patients With Relapsed Multiple Myeloma After Chemotherapy April 2008
NCT00025636 Unknown status Phase 3 Combination Chemotherapy and Peripheral Stem Cell Transplant in Treating Patients With Relapsed Hodgkin's Lymphoma July 2001
NCT02544425 Unknown status Phase 2 VP-16, Ifosfamide, Dexamethasone, L-asparaginase Chemotherapy in Patients With Extranodal Natural Killer T Cell Lymphoma (VIDL+ASCT) February 21, 2016 November 30, 2021
NCT03061656 Unknown status Phase 2 Tandem High Dose Chemotherapy With 131I-MIBG Treatment in High Risk Neuroblastoma January 1, 2009 December 31, 2018
NCT01572688 Unknown status N/A Safety and Efficacy Study of High Dose Melphalan to Treat Multiple Myeloma November 2011 June 2014
NCT00317408 Unknown status N/A Combination Chemotherapy Followed By Stem Cell Transplant in Treating Young Patients With Progressive or Relapsed Anaplastic Large Cell Lymphoma April 2004
NCT00084695 Unknown status Phase 2 Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases September 2003
NCT00209222 Unknown status Phase 3 Efficacy of R-CHOP vs R-CHOP/R-DHAP in Untreated MCL July 2004 December 2014
NCT00002599 Unknown status Phase 3 Combination Chemotherapy and Interferon Alfa With or Without Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloma September 1994
NCT00025103 Unknown status Phase 2 Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney May 2001
NCT00907036 Unknown status Phase 2 Fludarabine Phosphate, Melphalan, and Alemtuzumab Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed Hodgkin Lymphoma July 2009
NCT00908180 Unknown status Phase 2 Carmustine, Etoposide, Cytarabine, Melphalan, and Alemtuzumab Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma July 2009
NCT00003603 Unknown status Phase 3 Chemotherapy Plus Steroid Therapy in Treating Patients With Multiple Myeloma March 1998
NCT00025064 Unknown status Phase 2 Combination Chemotherapy With or Without Radiation Therapy and Peripheral Stem Cell Transplant in Treating Children With Hodgkin's Lymphoma January 2000
NCT04278040 Unknown status Phase 2 Inhalations of Ultra-low Doses of Melphalan for the Treatment of Non-cystic Fibrosis Bronchiectasis June 20, 2018 December 30, 2021
NCT00024193 Unknown status Phase 2 Chemotherapy and Surgery Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Neuroblastoma April 1999
NCT00020566 Unknown status Phase 3 Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing's Sarcoma February 2001
NCT00016887 Unknown status Phase 3 Chemotherapy Followed by Radiation Therapy and Peripheral Stem Cell Transplant Compared With Chemotherapy Plus Interferon Alfa in Treating Patients With Stage III or Stage IV Mantle Cell Lymphoma December 2000
NCT00983398 Unknown status Phase 1/Phase 2 Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors July 9, 2009 December 31, 2022
NCT00014339 Unknown status Phase 3 Chemotherapy With or Without Wobe-Mugos E in Treating Patients With Stage II or Stage III Multiple Myeloma March 2000
NCT03385096 Unknown status Phase 2/Phase 3 Mel vs BUCY+VP-16 Conditioning Regimen for MM Undergoing Auto-HSCT January 2, 2018 December 2021
NCT02109861 Unknown status Early Phase 1 Microdose Study of Melphalan, Bortezomib and Dexamethasone January 2014 December 2015
NCT00002653 Unknown status Phase 3 Combination Chemotherapy With or Without Cyclophosphamide and Prednisone in Treating Older Patients With Multiple Myeloma September 1993
NCT01619761 Unknown status Phase 1 NK Cells in Cord Blood Transplantation May 3, 2013 November 2021
NCT00002989 Unknown status Phase 3 Combination Chemotherapy With or Without Idarubicin and Peripheral Stem Cell Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome March 1997
NCT00085345 Withdrawn Phase 2 Melphalan, Arsenic Trioxide, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT00504101 Withdrawn Phase 1 Bortezomib, Arsenic Trioxide, and Melphalan in Treating Patients Undergoing an Autologous Stem Cell Transplant For Multiple Myeloma June 2007 June 2011
NCT01795430 Withdrawn N/A Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma July 2013
NCT01055301 Withdrawn Phase 2 S0833, Bortezomib, Thalidomide, Lenalidomide, Combination Chemotherapy, and Autologous Stem Cell Transplant in Treating Patients With Newly Diagnosed Multiple Myeloma July 2011 July 2011
NCT00085449 Withdrawn Phase 1/Phase 2 Alemtuzumab Plus Fludarabine and Melphalan With or Without Cyclosporine, Mycophenolate Mofetil, and Low-Dose Total-Body Irradiation Therapy Followed by Donor Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer May 2006 January 2007
NCT02701673 Withdrawn Phase 1/Phase 2 Belinostat Combined With Azacitidine/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Refractory or Relapsed Lymphoma June 2016
NCT01969942 Withdrawn Phase 1 A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcoma April 2013 October 2016
NCT03579927 Withdrawn Phase 1/Phase 2 CAR.CD19-CD28-zeta-2A-iCasp9-IL15-Transduced Cord Blood NK Cells, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Participants With B-cell Lymphoma October 3, 2019 October 3, 2019
NCT02114502 Withdrawn Phase 2 Carfilzomib/SAHA Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant in Myeloma September 2014
NCT03100877 Withdrawn Phase 1/Phase 2 Melphalan, Total Marrow Irradiation, and Autologous Stem Cell Transplantation in Treating Patients With High-Risk Multiple Myeloma January 2018 May 24, 2020
NCT02528877 Withdrawn Phase 1 Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis November 2015
NCT04282174 Withdrawn Phase 2 CD34+ Enriched Transplants From HLA-Compatible Patients With Hematologic Malignancies September 2022 March 1, 2030
NCT00003435 Withdrawn Phase 1 Antiviral Therapy Plus Either Peripheral Stem Cell or Umbilical Cord Blood Transplantation in Treating Patients Who Are HIV Positive and Have Hematologic Cancer May 1998
NCT00661336 Withdrawn Phase 1 A Phase I Trial of Normothermic Isolated Limb Infusion (ILI) With Melphalan Plus Buthionine Sulfoximine (BSO) in Patients With Locally Advanced Malignant Melanoma April 2008
NCT00723658 Withdrawn Phase 2 S0629, Observation or Combination Chemotherapy, Bortezomib, Thalidomide, and Rituximab Followed By Two Autologous Peripheral Blood Stem Cell Transplants in Treating Patients With Waldenstrom Macroglobulinemia September 2008
NCT02961816 Withdrawn Phase 2 Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed Lymphoma June 2017 June 2021
NCT00968396 Withdrawn Phase 2 Ex-Vivo Depletion of Myeloma Cells From Peripheral Blood Progenitor Cell Grafts February 2013
NCT03003728 Withdrawn Phase 2 2015-10: Expanded Natural Killer Cells and Elotuzumab for High-Risk Myeloma Post- Autologous Stem Cell Transplant (ASCT) November 1, 2019 July 8, 2020
NCT00972101 Withdrawn Phase 1 Infusion of Expanded Cord Blood T Cells September 2009 September 2011
NCT01769911 Withdrawn N/A Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma February 2015
NCT02507076 Withdrawn N/A Isolated Limb Perfusion With Melphalan in Treating Patients With Stage IIIB-IV Melanoma or Sarcoma April 2012 July 2014
NCT05228249 Withdrawn Phase 1 Loncastuximab Tesirine in Combination With Chemotherapy Prior to Stem Cell Transplant for the Treatment of Recurrent or Refractory Diffuse Large B-Cell Lymphoma April 2023 October 1, 2027
NCT00995059 Withdrawn Phase 1/Phase 2 Bortezomib Before Donor Stem Cell Transplant in Treating Patients With Multiple Myeloma
NCT01531244 Withdrawn Phase 1/Phase 2 Isolated Limb Infusion Chemotherapy With Targeted Gene Therapy for Advanced, Unresectable Extremity Melanoma December 2014 February 2016
NCT04521946 Withdrawn Phase 1 Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer January 14, 2021 December 20, 2022
NCT01251172 Withdrawn Phase 2 RO4929097 After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma December 2010
NCT04466475 Withdrawn Phase 1 Radioimmunotherapy (211At-OKT10-B10) and Chemotherapy (Melphalan) Before Stem Cell Transplantation for the Treatment of Multiple Myeloma January 27, 2024 September 30, 2027
NCT03506802 Withdrawn Phase 1 TCR Genetically Engineered PBMC and PBSC After Melphalan Conditioning Regimen in Treating Participants With Relapsed and Refractory Multiple Myeloma July 10, 2018 June 25, 2019
NCT02447055 Withdrawn Early Phase 1 Allogeneic Stem Cell Transplantation for Patients With Multiple Myeloma December 2015 June 2016