Fenretinide
Information
- Drug Name
- Fenretinide
- Description
- Entry(CIViC)
CIViC
[No Data.]
Annotation
| Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
|---|---|---|---|---|---|---|
| siRNA-mediated knockdown of ATF4 resulted in a a s... | ATF4 | ATF4 UNDEREXPRESSION | Resitance or Non-Reponse | true | MMMP | detail |
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06181760 | Completed | Phase 1 | A Study to Evaluate the Safety of Fenretinide in Healthy Volunteers | November 22, 2023 | February 13, 2024 |
| NCT00002646 | Completed | Phase 3 | Hormone Therapy in Treating Postmenopausal Women With Receptor-Positive Breast Cancer | October 1995 | |
| NCT00003075 | Completed | Phase 3 | Fenretinide in Treating Patients With Cervical Neoplasia | March 5, 1993 | May 1, 2001 |
| NCT00003099 | Completed | Phase 2 | Chemoprevention Therapy Plus Surgery in Treating Women With Breast Cancer | May 1996 | January 2003 |
| NCT00003191 | Completed | Phase 1 | Fenretinide in Treating Children With Solid Tumors | March 1998 | |
| NCT00026091 | Completed | Phase 2 | Fenretinide in Treating Patients With Recurrent or Metastatic Ovarian Epithelial or Primary Peritoneal Cancer | September 2001 | |
| NCT00053326 | Completed | Phase 2 | Fenretinide in Treating Children With Recurrent or Resistant Neuroblastoma | May 2003 | |
| NCT00077402 | Completed | Phase 2 | Fenretinide In Treating Patients With Advanced or Metastatic Hormone-Refractory Prostate Cancer | November 2003 | February 2011 |
| NCT00080899 | Completed | Phase 2 | Fenretinide in Treating Patients With Biochemically Recurrent Hormone-Naïve Prostate Cancer | June 2004 | January 2009 |
| NCT00098800 | Completed | N/A | Fenretinide in Preventing Ovarian Cancer in Participants Who Are at High Risk for Developing Ovarian Cancer and Planning to Undergo Surgery to Remove the Ovaries | October 2004 | November 2006 |
| NCT00104923 | Completed | Phase 1 | Fenretinide in Treating Patients With Refractory or Relapsed Hematologic Cancer | February 2005 | April 2017 |
| NCT00387504 | Completed | Phase 1 | Fenretinide in Treating Patients With Metastatic or Unresectable Malignant Solid Tumors | November 2006 | |
| NCT00429936 | Completed | Phase 2 | Study of Fenretinide in the Treatment of Geographic Atrophy Associated With Dry Age-Related Macular Degeneration | December 2006 | May 2010 |
| NCT00646230 | Completed | Phase 1 | N2004-03: Intravenous Fenretinide in Treating Young Patients With Recurrent or Resistant Neuroblastoma | December 2006 | March 2012 |
| NCT02141958 | Completed | Phase 1 | Safety Study of Fenretinide in Adult Patients With Cystic Fibrosis | April 2014 | February 2015 |
| NCT00001378 | Completed | Phase 1 | A Pilot Trial of Tamoxifen and 4-HPR (4-N-Hydroxyphenyl Retinamide) in Persons at High Risk for Developing Breast Cancer | January 1994 | November 2000 |
| NCT00003250 | Completed | Phase 1 | Fenretinide in Treating Patients With Solid Tumors | May 1998 | December 2008 |
| NCT00003601 | Completed | Phase 2 | Tretinoin With or Without Fenretinide in Treating Patients With Dysplastic Nevus Syndrome | February 23, 1999 | March 2, 2004 |
| NCT00004154 | Completed | Phase 3 | Fenretinide in Treating Patients Who Have Undergone Surgery for Bladder Cancer | July 30, 1998 | March 1, 2005 |
| NCT00004161 | Completed | Phase 2 | Fenretinide in Treating Patients With Leukoplakia of the Mouth | June 1997 | January 2004 |
| NCT00005819 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients With Advanced Solid Tumors | April 2000 | August 2006 |
| NCT00006080 | Completed | Phase 2 | Fenretinide in Treating Patients With Recurrent Malignant Glioma | September 25, 2000 | November 1, 2004 |
| NCT00006471 | Completed | Phase 2 | Fenretinide in Treating Patients With Recurrent or Metastatic Head and Neck Cancer | September 2000 | July 2004 |
| NCT00009971 | Completed | Phase 2 | Fenretinide in Treating Patients With Recurrent Small Cell Lung Cancer | November 2000 | |
| NCT00011973 | Completed | Phase 2 | Chemotherapy in Treating Patients With Advanced Kidney Cancer | December 2000 | October 2005 |
| NCT04234048 | Recruiting | Phase 1 | Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma | December 18, 2023 | November 2025 |
| NCT00546455 | Suspended | Phase 2 | A Randomized, Double-blind Study of the Effects of Fenretinide Administered in Subjects With Obesity | December 2007 | January 2099 |
| NCT01479192 | Terminated | Phase 3 | Fenretinide in Healthy Young Women at Genetic and Familial Risk | December 2009 | December 2015 |
| NCT00075491 | Terminated | Phase 2 | Neoadjuvant and Adjuvant Fenretinide Compared With Adjuvant Fenretinide Alone in Treating Patients Who Are Undergoing Surgical Resection For Recurrent Glioblastoma Multiforme | December 2003 | |
| NCT00003223 | Terminated | Phase 2 | SWOG-9507, Fenretinide in Treating Patients With Neoplasia of the Mouth | December 1997 | March 2000 |
| NCT00017134 | Terminated | N/A | Fenretinide Followed by Surgery Compared With Surgery Alone in Preventing Ovarian Cancer in Patients at Increased Risk | September 2002 | |
| NCT01187810 | Terminated | Phase 1 | Fenretinide in Children With Recurrent/Resistant ALL, AML, and NHL | August 2010 | April 2018 |
| NCT00288067 | Terminated | Phase 1/Phase 2 | Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma | October 2005 | July 2013 |
| NCT00009932 | Unknown status | Phase 1 | Combination Chemotherapy in Treating Patients With Solid Tumors | January 2001 | |
| NCT02495415 | Unknown status | Phase 2 | Trial of Intravenous Fenretinide Emulsion for Patients With Relapsed/Refractory Peripheral T-cell Lymphomas | December 2016 | December 2021 |
| NCT00534898 | Withdrawn | Phase 3 | Bexarotene and Fenretinide as Addition to Antipsychotic Treatment in Schizophrenia Patients |