genital herpes
Information
- Disease name
- genital herpes
- Disease ID
- DOID:8704
- Description
- "A herpes simplex that results_in infection located_in genital system, or located_in rectum, has_material_basis_in Human herpesvirus 1 or has_material_basis_in Human herpesvirus 2, which is transmitted_by sexual contact. The infection has_symptom sores, has_symptom fever, and has_symptom swollen glands." [url:http\://www.cdc.gov/std/herpes/stdfact-herpes.htm]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06033261 | Active, not recruiting | Phase 1/Phase 2 | A Study of mRNA-1608, a Herpes Simplex Virus -2 (HSV-2) Therapeutic Candidate Vaccine, in Healthy Adults 18 to 55 Years of Age With Recurrent HSV-2 Genital Herpes | September 6, 2023 | June 4, 2025 |
| NCT00129818 | Completed | Phase 4 | A Study to Evaluate the Effect of Famciclovir in Reducing Herpes Virus Shedding | July 2004 | October 2005 |
| NCT00231049 | Completed | Phase 1 | Trial Evaluating Safety, Tolerability and Immune Response of AG-707 | March 2006 | |
| NCT00262106 | Completed | Phase 3 | Trial to Evaluate PRO 2000/5 Gels for the Prevention of Vaginally Acquired HIV Infection | October 2005 | September 2009 |
| NCT00306787 | Completed | Phase 3 | Efficacy and Safety of Famciclovir 1-day Treatment Compared to 3-day Treatment With Valacyclovir in Adults With Recurrent Genital Herpes | March 2006 | February 2008 |
| NCT00362297 | Completed | Phase 4 | Randomized Trial to Evaluate Suppressive Effect of High-Dose Acyclovir Versus Once-Daily Valacyclovir on Persons With HSV-2 | September 2006 | September 2011 |
| NCT00477334 | Completed | Phase 4 | Patient-initiated Episodic Treatment of Recurrent Genital Herpes in Black Patients | June 2007 | March 2009 |
| NCT00495573 | Completed | HSV-2 Shedding Resolution After Acyclovir Treatment | June 2007 | March 2012 | |
| NCT00527618 | Completed | Phase 4 | Trial to Study the Effect of Dose of Herpes Simplex Virus-2 (HSV-2) Suppressive Therapy on HSV and HIV | December 2007 | March 2011 |
| NCT00723229 | Completed | Phase 4 | A Randomized Trial to Evaluated the Suppressive Effect of Acyclovir on Rapidly Cleared HSV-2 Reactivation | August 2008 | September 2011 |
| NCT00808405 | Completed | N/A | GUD Clinical and Virologic Response to Acyclovir in HIV Negative African Women | January 2009 | July 2010 |
| NCT01112956 | Completed | Serologic Assays for the Diagnosis of Herpes Simplex Virus Type 2 | July 2009 | February 2011 | |
| NCT01132716 | Completed | N/A | Bioequivalency Study of Valacyclovir Hydrochloride 1000 mg Under Fed Conditions | September 2006 | September 2006 |
| NCT01132729 | Completed | N/A | Bioequivalency Study of Valacyclovir Hydrochloride 1000 mg Under Fasting Conditions | September 2006 | September 2006 |
| NCT01281007 | Completed | Phase 3 | Efficacy of Oral Famciclovir 125mg Comparing to Aciclovir 200 mg Treatment in Patients With Active Recurrent Genital Herpes | July 2012 | March 2015 |
| NCT01346475 | Completed | Phase 4 | Randomized Trial to Evaluate Suppressive Effect of High-Dose Valacyclovir Versus Once-Daily Valacyclovir on Persons With HSV-2 | November 2008 | September 2011 |
| NCT01390805 | Completed | Special Drug Use Investigation for VALTREX (Valaciclovir) (Suppression Prophylaxis) | November 2006 | March 2011 | |
| NCT03080961 | Completed | N/A | The VIBLOK SAfety and perFormancE Trial | March 27, 2017 | November 13, 2017 |
| NCT03831165 | Completed | Phase 4 | Melatonin Effects on Genital Herpes in Brazilian Women | September 2, 2015 | December 28, 2021 |
| NCT05500053 | Completed | A Study of the Characteristics of Patients Diagnosed With Recurrent Symptomatic Genital Herpetic Disease | August 3, 2022 | December 31, 2022 | |
| NCT03595995 | Not yet recruiting | Phase 2 | A Phase 2 Trial to Evaluate the Safety and Efficacy of UB-621 | June 1, 2023 | June 30, 2024 |
| NCT05675228 | Recruiting | Knowledge of Young Adults About Genital Herpes | December 2, 2022 | July 1, 2023 | |
| NCT01765114 | Terminated | Phase 2 | A Study to Investigate the Efficacy, Safety and Tolerability of PEG in Patients With Genital Herpes | February 2013 | August 2014 |
| NCT03146403 | Terminated | Phase 2 | Maintenance Dose Study of GEN-003 in Subjects With Genital Herpes Infection | May 24, 2017 | June 11, 2018 |
| NCT00495716 | Terminated | Phase 4 | Effect of HSV-2 Suppressive Therapy on Sexual Behavior | January 2008 | June 2010 |
| NCT04222985 | Terminated | Phase 1 | Safety and Efficacy of 4 Investigational HSV 2 Vaccines in Adults With Recurrent Genital Herpes Caused by HSV 2 | February 18, 2020 | May 19, 2021 |
| NCT01658826 | Terminated | Phase 2 | Safety and Efficacy Comparator Trial of a New Drug Against Genital Herpes | October 2012 | July 2013 |
| NCT00124878 | Unknown status | Phase 3 | Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the Community | August 2003 | September 2009 |
- Disase is a (Disease Ontology)
- DOID:8566
- Cross Reference ID (Disease Ontology)
- ICD9CM:054.1
- Cross Reference ID (Disease Ontology)
- MESH:D006558
- Cross Reference ID (Disease Ontology)
- NCI:C14364
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:154333002
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0019342
- Exact Synonym (Disease Ontology)
- Genital herpes simplex
- Exact Synonym (Disease Ontology)
- Herpes Genitalis
- Exact Synonym (Disease Ontology)
- venereal herpes
- Exact Synonym (Disease Ontology)
- Virus-Genital Herpes