herpes simplex
Information
- Disease name
- herpes simplex
- Disease ID
- DOID:8566
- Description
- "A viral infectious disease that results_in_formation_of lesions, located_in mouth, located_in face, located_in genitalia, or located_in hands, has_material_basis_in Human herpesvirus 1 or has_material_basis_in Human herpesvirus 2, which are transmitted_by direct contact with an active lesion or body fluid of an infected person." [url:http\://en.wikipedia.org/wiki/Herpes_simplex, url:https\://www.aad.org/public/diseases/a-z/herpes-simplex-overview]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05298254 | Active, not recruiting | Phase 1/Phase 2 | A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Targeted Immunotherapy Against HSV in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent Genital Herpes | March 7, 2022 | July 5, 2026 |
| NCT00000635 | Completed | N/A | Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients With AIDS: Open Label Pilot Study of Topical Trifluridine | April 1992 | |
| NCT00000654 | Completed | Phase 2 | The Tolerance of HIV-Infected Patients With Herpes Group Virus Infections to Oral Doses of FIAU | February 1993 | |
| NCT00000985 | Completed | Phase 3 | Comparison of Foscarnet Versus Vidarabine in the Treatment of Herpes Infection in Patients With AIDS Who Have Not Had Success With Acyclovir | October 1990 | |
| NCT00001115 | Completed | N/A | The Effect of Acyclovir Treatment of the Herpes Simplex Virus (HSV) Infection on HIV Levels in the Blood | June 2005 | |
| NCT00001648 | Completed | Structure of the Herpes Simplex Virus Receptor | August 20, 1997 | April 13, 2010 | |
| NCT00001649 | Completed | Phase 3 | Valaciclovir to Prevent Transmission of Herpes Simplex Virus | August 1997 | August 2003 |
| NCT00002000 | Completed | N/A | A Study to Compare the Efficacy and Safety of Valacyclovir Hydrochloride ( 256U87 ) Versus Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected Patients | ||
| NCT00002021 | Completed | N/A | An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies | ||
| NCT00002084 | Completed | N/A | A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients | ||
| NCT00002116 | Completed | Phase 1 | A Phase I/II Study of the Safety and Efficacy of Topical 1-(S)-(3-Hydroxy-2-Phosphonylmethoxypropyl)Cytosine Dihydrate (Cidofovir; HPMPC) in the Treatment of Refractory Mucocutaneous Herpes Simplex Disease in Patients With AIDS | ||
| NCT00002144 | Completed | Phase 1 | The Pilot Study of Foscarnet Cream in the Treatment of Mucocutaneous Herpes Simplex Virus Infections in Immunocompromised Patients Unresponsive to Acyclovir Treatment | ||
| NCT00002181 | Completed | N/A | Cidofovir as a Treatment for Herpes Simplex in Patients With AIDS | ||
| NCT00000139 | Completed | Phase 3 | Herpetic Eye Disease Study (HEDS) II | October 1992 | |
| NCT00002272 | Completed | N/A | An Open, Multicenter Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies | ||
| NCT00002310 | Completed | N/A | SP-303T Applied to the Skin of Patients With Herpes Simplex Virus (HSV) Infection and AIDS Who Have Not Had Success With Acyclovir | ||
| NCT00002404 | Completed | N/A | The Effect of Valacyclovir on the Detection of HIV From Genital Herpes Lesions in HIV-Infected Patients | ||
| NCT00004644 | Completed | Phase 1/Phase 2 | Phase I/II Study of High-Dose Acyclovir for Central Nervous System or Disseminated Neonatal Herpes Simplex Virus Infection | February 1995 | |
| NCT00004757 | Completed | Phase 3 | Phase III Randomized, Placebo-Controlled Study of Acyclovir Oral Suspension for Neonatal Herpes Simplex Virus Infection Limited to the Skin, Eyes, and Mouth | August 1992 | |
| NCT00002186 | Completed | N/A | Double-Blind Placebo-Controlled Study Comparing the Combination of 15% SP-303 Gel With Acyclovir Versus Acyclovir Alone for the Treatment of Recurrent Herpes Simplex Virus (HSV) Infections in Subjects With Acquired Immunodeficiency Syndrome (AIDS) | ||
| NCT00973466 | Completed | Prevalence of Sexually Transmitted Infections (STIs) in HIV-infected Patients | May 2009 | June 2010 | |
| NCT00985335 | Completed | Phase 1 | Effectiveness of TheraNeem Lip Therapy for Herpes Simplex Labialis | August 2009 | March 2011 |
| NCT01176409 | Completed | Phase 3 | Can Valacyclovir Attenuate Inflammation in Antiretroviral-Treated HIV-Infected Individuals With Herpes Simplex Virus Type 2? | September 2010 | August 2013 |
| NCT01602562 | Completed | Phase 3 | Valaciclovir Hydrochloride Phase III for Hematopoietic Stem Cell Transplantation Patients | May 7, 2012 | May 24, 2013 |
| NCT01794897 | Completed | Phase 4 | Valacyclovir Augmentation for Cognitive and Functional Remediation in Schizophrenia | February 2013 | September 2016 |
| NCT01959295 | Completed | Phase 3 | Phase III Study of ASP2151 in Herpes Simplex Patients | August 2013 | |
| NCT02209324 | Completed | Phase 3 | Open-label Study of ASP2151 in Herpes Simplex Patients | November 2013 | |
| NCT02685956 | Completed | Clinical Evaluation of the Sentosa SA HSV1/2 Qualitative PCR Test | April 2016 | April 7, 2017 | |
| NCT02997982 | Completed | Phase 2 | Feasibility and Effects of Valaciclovir Treatment in Persons With Early Alzheimer's Disease | December 2016 | March 4, 2020 |
| NCT04239521 | Completed | The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata | October 1, 2020 | November 28, 2022 | |
| NCT04664127 | Completed | Study of the Efficacy and Safety of Combined Treatment of Patients With Severe Herpes Simplex (HSV) Infection by Valacyclovir and Interferon Inducer Kagocel | October 30, 2017 | October 29, 2018 | |
| NCT05989672 | Completed | Phase 1 | A Study on the Reactogenicity, Safety and Immune Response of a Targeted Immunotherapy Against HSV in Healthy Japanese Participants Aged 18-40 Years | August 8, 2023 | April 24, 2024 |
| NCT00006135 | Completed | Phase 3 | Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Limited to Skin, Eyes, and Mouth | June 1997 | |
| NCT00031447 | Completed | Phase 3 | Acyclovir Herpes Simplex Virus (HSV) Skin, Eye, and Mouth | August 1999 | April 2008 |
| NCT00031460 | Completed | Phase 3 | Acyclovir for Herpes Infections Involving the Central Nervous System in Neonates | December 1997 | April 2008 |
| NCT00098059 | Completed | Phase 3 | Famciclovir Pediatric Formulation in Children 1 to 12 Years of Age With Herpes Simplex Infection | February 2005 | December 2007 |
| NCT00161434 | Completed | Phase 4 | A Study of Valacyclovir to Suppress HSV and HIV Shedding in Coinfected Persons | March 2003 | June 2006 |
| NCT00164424 | Completed | Phase 2/Phase 3 | Episodic Acyclovir Therapy for Genital Ulcers | March 2005 | July 2011 |
| NCT00213031 | Completed | Phase 2 | Safety, Acceptability and Preliminary Effectiveness of PC-515 for Vaginal Use as a Possible Microbicide | February 2000 | December 2001 |
| NCT00224471 | Completed | Phase 3 | Study to Compare Safety and Immunogenicity of Commercial Scale Consistency Lots of Herpes Simplex Vaccine | December 2003 | January 2006 |
| NCT00224484 | Completed | Phase 3 | Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years Old | April 7, 2004 | July 24, 2007 |
| NCT00297206 | Completed | Phase 1 | A Safety And Tolerability Study Of Valaciclovir Oral Suspension In Infants And Children | January 25, 2003 | February 28, 2007 |
| NCT00378976 | Completed | Phase 3 | HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1, HSV-2 Co-infected Men. | August 2003 | July 2004 |
| NCT00448227 | Completed | Phase 2 | Pharmacokinetics, Acceptability and Safety of Famciclovir in Infants (1 Month to Less Than 12 Months) With Herpes Simplex Infection | October 2007 | |
| NCT00465205 | Completed | Phase 3 | HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1 Co-infected Persons | January 2005 | December 2007 |
| NCT00530777 | Completed | Phase 2 | HSV-2 Suppression to Reduce Maternal HIV-1 RNA Levels During Pregnancy and Breastfeeding | April 2008 | August 2010 |
| NCT00642785 | Completed | Activation of Alternative Cellular Energy (ACE) Pathway in the Therapy of Herpes Virus Infections | January 2008 | April 2008 | |
| NCT00698893 | Completed | Phase 1 | Evaluation of Safety of Candidate gD Vaccine, With or Without MPL in Healthy Herpes Simplex Virus-positive Adults | May 1, 1992 | July 1, 1992 |
| NCT00699764 | Completed | Phase 3 | Safety of a Herpes Simplex Candidate Vaccine (gD2t) With MPL and Its Efficacy to Prevent Genital Herpes Disease | March 1996 | October 1999 |
| NCT00855309 | Completed | Phase 3 | Acyclovir in Preventing Herpes Simplex Virus Infection in Patients With Neutropenia | November 2008 | November 2013 |
| NCT04065971 | Recruiting | Phase 4 | Randomized, Placebo-controlled, Double-blind Study of 2LHERP® in Orofacial Herpes Infections. | March 10, 2020 | June 30, 2024 |
| NCT05468619 | Recruiting | Phase 1 | Neonatal Phase 1 Valacyclovir Study | September 23, 2022 | November 29, 2024 |
| NCT06134492 | Recruiting | Phase 3 | Acyclovir in Mechanically Ventilated Patients With Pneumonia and HSV-1 in BAL | February 20, 2024 | December 2026 |
| NCT00138320 | Terminated | Herpevac Neonatal Substudy | August 2005 | May 2007 | |
| NCT04762511 | Terminated | Phase 1 | A Study on the Reactogenicity, Safety and Immune Response of a Vaccine Against Herpes Simplex Virus (HSV)-2 in Healthy Participants Aged 18-40 Years | March 2, 2021 | May 26, 2021 |
| NCT00194415 | Terminated | N/A | A Study of HSV Testing Among Pregnant Women | January 2004 | November 2006 |
| NCT03178747 | Unknown status | Phase 3 | Tzanck Smear With Methylene Blue Stain for Herpes | March 7, 2017 | March 6, 2018 |
| NCT00006132 | Unknown status | Phase 3 | Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous System | June 1997 | |
| NCT00587496 | Unknown status | Phase 1 | 30-Day Trial of Oral Valtrex or Valtrex Plus Aspirin on Shedding of HSV DNA in Tears and Saliva of Volunteers | April 2006 | July 2008 |
| NCT00005663 | Unknown status | Phase 3 | A Study of Valacyclovir as Treatment for Genital Herpes Simplex Virus in HIV-Infected Patients | June 1999 | |
| NCT00001054 | Withdrawn | Phase 1 | The Safety and Effectiveness of Valacyclovir HCl in the Treatment of Herpes Simplex or Varicella/Zoster Infections in HIV-1 Infected Children | January 2001 | |
| NCT02349828 | Withdrawn | Phase 2/Phase 3 | Antiviral Prophylaxis in a Burn Population | September 2015 | April 2016 |
- Disase is a (Disease Ontology)
- DOID:934
- Cross Reference ID (Disease Ontology)
- ICD10CM:B00.9
- Cross Reference ID (Disease Ontology)
- ICD9CM:054
- Cross Reference ID (Disease Ontology)
- MESH:D006561
- Cross Reference ID (Disease Ontology)
- NCI:C155871
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:88594005
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0019348
- Exact Synonym (Disease Ontology)
- Herpesvirus hominis disease
- MeSH unique ID (MeSH (Medical Subject Headings))
- D006561