interstitial lung disease

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Information
Disease name
interstitial lung disease
Disease ID
DOID:3082
Description
"A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough." [url:https\://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215823/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
NCT ID Status Phase Summary Start date Completion date
NCT05716022 Active, not recruiting Hiatal Hernia and Pulmonary Involvement January 5, 2023 January 2025
NCT03485378 Active, not recruiting N/A Assessment of Precision Irradiation in Early NSCLC and Interstitial Lung Disease September 20, 2018 September 20, 2026
NCT02479126 Active, not recruiting Interstitial Lung Diseases in the Veterans Administration July 2016 June 2023
NCT03727568 Active, not recruiting N/A Study Comparing Two Different Methods of Cryobiopsy in the Interstitial Lung Diseases September 11, 2018 December 31, 2022
NCT03295279 Active, not recruiting WTC Chest CT Imaging Archive September 1, 2012 August 2026
NCT05630599 Active, not recruiting Remote Assessment of Lung Disease and Impact on Physical and Mental Health July 26, 2021 March 31, 2023
NCT04136223 Active, not recruiting Rheumatoid Arthritis-Associated Interstitial Lung Disease: Characterization of Lung Disease Progression March 1, 2021 May 31, 2024
NCT04227535 Active, not recruiting Deciphering Rheumatoid Arthritis-associated Interstitial Lung Disease Pathogenesis 2 February 3, 2020 October 1, 2027
NCT05068869 Active, not recruiting N/A Digital Outpatient Services September 12, 2021 December 31, 2024
NCT04928586 Active, not recruiting Phase 4 Immunosuppressant Combined With Pirfenidone in CTD-ILD August 16, 2019 June 1, 2025
NCT03215927 Active, not recruiting Phase 2 Abatacept for the Treatment of Myositis-associated Interstitial Lung Disease June 1, 2017 July 30, 2023
NCT04299945 Active, not recruiting N/A Effects of Drinking Beetroot Juice on Exercise Performance in Patients With Fibrotic Interstitial Lung Disease January 29, 2020 December 31, 2025
NCT05714787 Active, not recruiting Opportunistic Screening for Osteoporotic Vertebral Fractures in Patients With Diffuse Interstitial Lung Disease January 23, 2017 June 30, 2023
NCT04760548 Active, not recruiting Segmentation of Structural Abnormalities in Chronic Lung Diseases January 1, 2008 February 17, 2024
NCT05760508 Active, not recruiting Novel Markers of Disease Progression in Interstitial Lung Disease July 23, 2018 January 2024
NCT05572996 Available Inhaled Treprostinil Expanded Access Program in Pulmonary Hypertension Associated With Interstitial Lung Disease
NCT01462006 Completed N/A Double-blind Placebo-controlled Pilot Study of Sirolimus in Idiopathic Pulmonary Fibrosis (IPF) October 2011 March 2016
NCT01570764 Completed Phase 3 Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease January 14, 2013 February 22, 2018
NCT01600352 Completed Specific Autoantibody Testing in Patients With Interstitial Lung Disease May 2012 April 2017
NCT01713413 Completed N/A Effects of an Oxymizer on Endurance Time in Patients With Chronic Lung Diseases February 2012 March 2014
NCT01714518 Completed Cryobiopsy vs. VATS in Diagnosis of Interstitial Lung Diseases October 16, 2012 June 30, 2017
NCT01789996 Completed N/A The Six Minute Walk Test: Influence of Instruction on Results June 2010 December 2014
NCT01862926 Completed Phase 2/Phase 3 Rituximab Versus Cyclophosphamide in Connective Tissue Disease-ILD November 2014 January 2021
NCT01874223 Completed Prospective Validation of Cough, Dyspnea, and Quality of Life Questionnaires in Patients With IPF June 2013 November 4, 2018
NCT01894113 Completed N/A Prospective, Randomised Multicenter Study Comparing the Efficacy of Transbronchial Forceps Biopsy With Cryobiopsy to Diagnose Interstitial Lung Disease. January 2012 May 2014
NCT01906931 Completed Phase 2 Ambulatory Oxygen for ILD August 2013 February 2014
NCT01955824 Completed Phase 2/Phase 3 A Trial on Clinical Efficacy of 1% Versus 2% Lignocaine in Cough Suppression and Pain Relief in Patients Undergoing Flexible Bronchoscopy May 2014 November 2014
NCT01972685 Completed N/A Comparison of Transbronchial, Cryoprobe and VATS Biopsy For the Diagnosis of Interstitial Lung Disease (ILD) June 2013 March 30, 2018
NCT02019641 Completed N/A The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients With Interstitial Lung Disease May 23, 2015 May 24, 2023
NCT02036970 Completed Phase 2 Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT May 31, 2014 May 16, 2018
NCT02075762 Completed N/A Comparison of Transbronchial, Cryoprobe, and VATS Biopsy for the Diagnosis of Interstitial Lung Disease August 2013 December 2018
NCT02143687 Completed Phase 4 Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Exercise Performance May 2014 October 2021
NCT06007040 Completed Interstitial Lung Disease Associated January 2012 December 2021
NCT02197364 Completed The Role of KL-6 in the Clinical Diagnosis of ILD December 2013 May 2014
NCT02201654 Completed N/A Stylet vs No Stylet During EBUS TBNA June 2014 September 2015
NCT05993520 Completed Effects of Respiratory Muscle Functions on Interstitial Lung Disease: Sleep Quality, Dyspnea, and Fatigue June 1, 2020 June 1, 2023
NCT02426229 Completed Phase 1 Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma February 2016 June 21, 2018
NCT02497144 Completed N/A Neuromuscular Electrical Stimulation in Patients With Interstitial Lung Disease July 15, 2015 December 30, 2018
NCT05963048 Completed Phase 2/Phase 3 Rituxmab Versus IL-6 in Treating ILD December 1, 2021 June 1, 2023
NCT02594839 Completed Phase 1/Phase 2 Safety and Efficacy of Allogeneic Mesenchymal Stem Cells in Patients With Rapidly Progressive Interstitial Lung Disease February 2013 January 2018
NCT02622022 Completed Phase 4 Palliation of Dyspnea With Morphine in Patients With Interstitial Lung Disease January 2016 February 6, 2019
NCT02622412 Completed N/A Evaluation of a Multi-professional Breathlessness Service for Patients With Breathlessness Due to Any Advanced Disease March 2, 2015 April 30, 2019
NCT02630316 Completed Phase 2/Phase 3 Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE February 3, 2017 December 26, 2019
NCT05914909 Completed Phase 1 Safety, Tolerability, PK and PD Study of AD-214 Administered to Healthy Volunteers and Patients With Interstitial Lung Disease or Chronic Kidney Disease July 17, 2023 February 9, 2024
NCT02636452 Completed Cardiopulmonary Exercise Testing in Interstitial Lung Disease October 31, 2013 September 30, 2017
NCT00362739 Completed Blood Collection From Individuals With Lung Disease for Genetic Studies September 2005 August 2015
NCT05784207 Completed An In Silico Trial to Evaluate Prospectively the Performance of a Radiomics Algorithm for UIP Compared to Medical Doctors June 1, 2017 December 30, 2021
NCT03729583 Completed N/A The Effects of Breathing Retraining in Patients With Interstitial Lung Diseases July 1, 2017 May 18, 2018
NCT04481074 Completed N/A Inspiratory Muscle Training in Patients With Interstitial Lung Disease July 30, 2020 April 30, 2021
NCT04503044 Completed ILAs in CT Lung Cancer Screening Population January 30, 2021 June 30, 2021
NCT04803617 Completed Investigation of Pectoralis Muscle Strength in Elderly With Interstitial Lung Disease January 23, 2017 June 23, 2017
NCT04574050 Completed N/A SELF-BREATHE RCT for Chronic Breathlessness January 11, 2021 January 30, 2022
NCT04619680 Completed Phase 4 The Study of the Use of Nintedanib in Slowing Lung Disease in Patients With Fibrotic or Non-Fibrotic Interstitial Lung Disease Related to COVID-19 November 18, 2020 March 1, 2024
NCT00820729 Completed Biomarkers in Pulmonary Hypertension Associated to Interstitial Lung Disease March 2009 March 2011
NCT00882817 Completed Phase 4 Pulmonary Rehabilitation in Interstitial Lung Diseases April 2009 November 2011
NCT00883129 Completed Phase 2 Comparison of Therapeutic Regimens for Scleroderma Interstitial Lung Disease (The Scleroderma Lung Study II) September 2009 November 2015
NCT00926523 Completed Biomarkers in the Evaluation of Chronic Lung Disease June 2009 March 2011
NCT04711057 Completed N/A CENTR(AR): Lungs Moving April 1, 2021 December 31, 2023
NCT04715347 Completed Interstitial Lung Disease Within a Lung Cancer Screening November 11, 2017 June 30, 2020
NCT01055730 Completed The Impact of Pulmonary Rehabilitation in Interstitial Lung Disease February 2010 January 2013
NCT01064609 Completed N/A "Diagnostic Yield and Safety of Transbronchial Lung Biopsy Using Cryoprobes Versus Conventional Forceps. June 2011 September 2012
NCT00319033 Completed Phase 2/Phase 3 Open-label Study With Bosentan in Interstitial Lung Disease July 2004 February 2006
NCT06260930 Completed Value of Chest Ultrasonography in ILD Screening January 2017 December 2019
NCT03416075 Completed Mechanical Ventilation in Interstitial Lung Disease January 1, 2011 December 31, 2017
NCT05227443 Completed N/A Effects of Exercise Training on Respiratory Performance in Patients With Fibrosing Interstitial Lung Diseases January 16, 2020 July 30, 2021
NCT05095363 Completed N/A Palliative Care Planner (PCplanner) March 16, 2022 March 31, 2023
NCT00504361 Completed Blood Collection From Individuals With Lung Disease for Genetic Studies (Qatar) May 2006 May 2012
NCT03516994 Completed N/A Reducing Disparities in the Quality of Advance Care Planning for Older Adults August 1, 2018 April 15, 2024
NCT03599414 Completed CASPA: CArdiac Sarcoidosis in PApworth June 29, 2017 March 8, 2023
NCT03641742 Completed Families-At-risk for Interstitial Lung Disease Study January 15, 2018 July 1, 2023
NCT04988282 Completed Phase 4 Systemic Corticosteroids in Treatment of Post-COVID-19 Interstitial Lung Disease May 24, 2021 January 31, 2022
NCT04435327 Completed Lung Damage Caused by SARS-CoV-2 Pneumonia (COVID-19) October 5, 2020 March 18, 2022
NCT04982809 Completed N/A Cost-effectiveness Analysis of Three Corticosteroids in ILDs July 1, 2018 March 15, 2020
NCT04946708 Completed N/A Virtual Exercise Program in Interstitial Lung Disease (ILD) Patients September 1, 2021 May 17, 2022
NCT00677560 Completed The Natural History of Small Airways Physiology in Diseased and Healthy States June 22, 2010 July 10, 2013
NCT00678821 Completed Phase 2 Aerobic Exercise in Patients With Pulmonary Hypertension June 12, 2008 September 23, 2015
NCT03929120 Completed Phase 1 Allogeneic Bone Marrow Mesenchymal Stem Cells for Patients With Interstitial Lung Disease (ILD) & Connective Tissue Disorders (CTD) November 5, 2019 February 2, 2022
NCT04939558 Completed Cardiorespiratory Diagnostic Study June 2, 2021 November 30, 2022
NCT04061356 Completed Assessment of Exhaled Breath Condensate Hydrogen Peroxide (EBC H2O2) as Measured Using a New Device (Inflammacheck™) in Patients With Interstitial Lung Disease, Lung Cancer and Healthy Volunteers. October 30, 2018 September 14, 2019
NCT00705133 Completed Phase 2 Treprostinil Therapy For Patients With Interstitial Lung Disease And Severe Pulmonary Arterial Hypertension July 2008 April 2011
NCT04138173 Completed N/A Enhancing Physical Activity in Patients With Interstitial Lung Disease January 14, 2020 January 6, 2022
NCT04159584 Completed N/A Pilot Study: The Effects of Medical Music on Anxiety in Patients With ILD April 15, 2019 September 11, 2019
NCT04184180 Completed Effects of Inpatient Pulmonary Rehabilitation on Frailty in Patients After Lung-Transplantation December 2, 2019 March 16, 2020
NCT04879082 Completed Identification Of Occupational Exposures In Patients With ILD May 15, 2020 April 15, 2021
NCT04273867 Completed Assessing Health Related Quality of Life in Hypersensitivity Pneumonitis July 10, 2020 February 22, 2023
NCT04850521 Completed Remote Monitoring of Interstitial Lung Disease August 3, 2021 July 7, 2022
NCT04413149 Completed Anti-neutrophil Cytoplasmic Antibody in Interstitial Lung Disease. April 1, 2014 April 1, 2020
NCT04415671 Completed Phase 1 Phase 1 Safety, Tolerability, PK & PD Study of AD-214 Administered to Healthy Volunteers June 19, 2020 February 8, 2022
NCT04813900 Completed N/A Correlation Between Lung UltraSound Score and Hypoxemia for Interstitial Syndrome in Emergency Department April 1, 2021 August 30, 2021
NCT04430491 Completed To Evaluate the Use of Radiomics to Classify Between Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease January 1, 2005 July 1, 2017
NCT02858791 Completed MIF- Thyroxine Interactions in the Pathogenesis of Pulmonary Arterial Hypertension February 2013 December 21, 2017
NCT02896205 Completed Phase 3 Study to Compare the Efficacy of Mycophenolate Mofetil in Systemic Sclerosis Related Early Interstitial Lung Disease October 2016 July 1, 2017
NCT02934750 Completed N/A Pursed Lip Breathing in Interstitial Lung Disease October 2016 January 30, 2017
NCT02988388 Completed Lung Tissue Research Consortium February 23, 2017 February 21, 2019
NCT03018756 Completed Phase 3 Nebulized Fentanyl in Patients With Mild to Moderate Interstitial Lung Disease and Chronic Dyspnea January 2017 November 30, 2020
NCT03040674 Completed An Observational Outcomes Study for Autologous Cell Therapy Among Patients With COPD and Interstitial Lung Disease January 3, 2017 December 31, 2020
NCT03044431 Completed Autologous Stem Cell Treatment for Chronic Lung Disease Study April 1, 2016 June 9, 2017
NCT03068091 Completed N/A Assessment of Lung Movement With Computed Tomography (CT) July 1, 2017 October 31, 2018
NCT03221257 Completed Phase 2 Scleroderma Lung Study III - Combining Pirfenidone With Mycophenolate November 28, 2017 June 13, 2022
NCT03261037 Completed N/A A Study to Characterize the Disease Behavior of Idiopathic Pulmonary Fibrosis (IPF) and Interstitial Lung Disease (ILD) During the Peri-Diagnostic Period December 25, 2017 November 27, 2019
NCT00453713 Completed Race, Ethnicity, and Diffuse Parenchymal Lung Disease July 2006 August 2013
NCT03300583 Completed Toward Self-management in ILD June 1, 2018 December 30, 2020
NCT03302702 Completed N/A Duration of Exercise Program in Interstitial Lung Diseases. January 2014 January 2016
NCT03336736 Completed The Role of Physical Activity and Diet Within Pulmonary Sarcoidosis November 7, 2017 June 15, 2018
NCT03388580 Completed Predictors for Bronchoalveolar Lavage (BAL) Recovery Rate Derived From Quantified Computed Tomography (qCT) January 2017 September 2017
NCT03396120 Completed The FVC/DLCO Ratio is a Useful Predictor of Pulmonary Hypertension in Patients With Interstitial Lung Disease February 2, 2017 December 31, 2017
NCT05311345 Completed Integration of Cryobiopsies for ILD Diagnoses- Experience Based on 250 Biopsy Procedures. November 6, 2015 April 1, 2020
NCT04896138 Enrolling by invitation University of Virginia Natural History Study August 28, 2018 August 31, 2035
NCT04905693 Enrolling by invitation Phase 3 Extension Study of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis September 6, 2022 June 2026
NCT04326036 Enrolling by invitation Early Phase 1 Use of cSVF Via IV Deployment for Residual Lung Damage After Symptomatic COVID-19 Infection March 25, 2020 January 31, 2024
NCT05564637 Enrolling by invitation Phase 2 A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary Hypertension March 13, 2023 June 2024
NCT04016181 Enrolling by invitation The Edinburgh Lung Fibrosis Molecular Endotyping (ELFMEN) Study June 14, 2007 December 1, 2036
NCT05001009 Enrolling by invitation N/A Goals of Care Conversations Study September 13, 2022 September 30, 2025
NCT05450276 Enrolling by invitation Patient-Reported Outcome Study of Project ECHO for ILD July 2022 March 2024
NCT05609201 Enrolling by invitation PRospective Evaluation of Interstitial Lung DIsease Progression With Quantitative CT June 1, 2023 October 31, 2024
NCT04930289 Enrolling by invitation Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs October 15, 2021 December 30, 2025
NCT04532346 Not yet recruiting Early Phase 1 Hydroxychloroquine in Children's Interstitial Lung Diseases With Genetic Causes March 2024 October 2026
NCT06125288 Not yet recruiting Risk Factors and Prognostic Parameters of Interstitial Lung Disease in Children December 2023 February 2025
NCT06235645 Not yet recruiting dEtection of rheumAtoid aRthritis - Interstitial Lung dIseasE by Thoracic ultRasound March 2024 September 2026
NCT03800017 Not yet recruiting N/A Skeletal Muscle Function in Interstitial Lung Disease June 1, 2024 December 31, 2026
NCT06388421 Not yet recruiting DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) August 1, 2024 November 30, 2030
NCT04897048 Not yet recruiting N/A Effect of Short-term Oxygen During CPET in ILD July 1, 2023 December 1, 2024
NCT03870828 Not yet recruiting Clinical Characteristics of Interstitial Pneumonia With Autoimmune Features (IPAF) - a Multicenter Prospective Study March 18, 2019 December 31, 2025
NCT06325696 Not yet recruiting Phase 2 H01 in Adults With Interstitial Lung Disease (The SOLIS Study) June 23, 2024 December 31, 2025
NCT05785065 Not yet recruiting Phase 2 Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung Disease December 2023 December 2026
NCT04719078 Not yet recruiting N/A Thorax MRI for Evaluation of Lung Morphology, Ventilation and Perfusion June 1, 2023 December 31, 2023
NCT05947422 Not yet recruiting CT Quantitative Assessment of Interstitial Lung Disease August 1, 2023 October 1, 2024
NCT06326957 Not yet recruiting N/A Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention (SELF-BREATHE) May 2024 July 2028
NCT06174207 Not yet recruiting N/A Hyperoxia During Pulmonary Rehabilitation in Chronic Lung Disease - Does it Matter? January 1, 2024 April 30, 2025
NCT06182956 Not yet recruiting N/A NIV Versus HFO for Acute Exacerbations of Interstitial Lung Diseases January 1, 2024 December 31, 2026
NCT06416163 Not yet recruiting FIBRotic Interstitial Lung Disease With Nocturnal hypOXaemia and EXercise Induced desaTuRAtion July 1, 2024 July 1, 2029
NCT06297096 Not yet recruiting Phase 3 Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Disease April 1, 2024 March 30, 2028
NCT05986318 Not yet recruiting Phase 2 Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease May 1, 2024 December 31, 2032
NCT05999838 Not yet recruiting HR Chest CT Visual Scoring, Spirometry and Health Related Quality of Life in Evaluating Severity of ILD Patients October 2023 February 2025
NCT06447831 Recruiting Assessing Functional Capacity in Directly and Remotely Monitored Home-based Settings: A Protocol for a Multinational Validation Study in Individuals With Chronic Respiratory Diseases February 2, 2024 January 2026
NCT01280994 Recruiting Phase 2 Hyperpolarized 129Xe MRI for Imaging Pulmonary Function January 2011 December 2025
NCT02748798 Recruiting Early Phase 1 Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders November 10, 2020 December 22, 2023
NCT03297775 Recruiting Rheumatoid Arthritis Patients at Risk for Interstitial Lung Disease June 22, 2017 June 2027
NCT03478826 Recruiting Creation of a Biospecimen Repository From Patients With Interstitial Lung Diseases (ILD) August 1, 2018 January 2028
NCT03630211 Recruiting Phase 2 Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis July 31, 2018 August 1, 2025
NCT03814317 Recruiting Phase 2 Inhaled Treprostinil in Sarcoidosis Patients With Pulmonary Hypertension January 30, 2020 July 29, 2025
NCT03901196 Recruiting Multi-elemental Imaging of Lung Tissues With LIBS (Laser-induced Breakdown Spectroscopy) January 22, 2020 January 22, 2025
NCT03901534 Recruiting N/A Assessment of Continuous Positive Airway Pressure Therapy in IPF January 1, 2023 December 31, 2025
NCT04095351 Recruiting Connective Tissue Diseases and Lung Manifestations December 9, 2019 October 1, 2034
NCT04328181 Recruiting N/A Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT) January 29, 2021 January 29, 2026
NCT04624490 Recruiting Phase 1 Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease November 2, 2020 October 26, 2026
NCT04664192 Recruiting Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research June 4, 2021 December 1, 2026
NCT04676594 Recruiting Genentech Validation Tool for Pulmonary Fibrosis October 4, 2020 October 30, 2024
NCT04708782 Recruiting Phase 3 Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis June 1, 2021 June 2025
NCT04778046 Recruiting Phase 2 Pulmonary Hypertension SOLAR November 8, 2023 December 30, 2024
NCT04925375 Recruiting Phase 2 Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease July 14, 2021 July 2025
NCT05007340 Recruiting ILD-SARDs Registry and Biorepository August 24, 2021 August 2026
NCT05120934 Recruiting Phase 2 Efficacy of Two Doses of Duloxetine & Amitriptyline in Interstitial Lung Disease-related Cough November 1, 2021 December 2025
NCT05177471 Recruiting Efficacy and Safety of JAK Inhibitors in Systemic Sclerosis-associated Interstitial Lung Disease January 19, 2022 July 4, 2024
NCT05246293 Recruiting Phase 2 Tofacitinib in the Treatment of Rheumatoid Arthritis-related Interstitial Lung Disease. August 8, 2022 March 2, 2025
NCT05255991 Recruiting Phase 3 Multinational Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis October 4, 2022 June 2025
NCT05270668 Recruiting Phase 2 Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Systemic Sclerosis Associated With Interstitial Lung Disease (SSc-ILD) (MK-7240-007) July 13, 2022 December 30, 2028
NCT05345795 Recruiting Interstitial Lung Disease Trajectories in Patients With Systemic Sclerosis May 1, 2023 September 1, 2024
NCT05365802 Recruiting Early Phase 1 FAPI PET for Lung Fibrosis November 16, 2021 December 2026
NCT05372926 Recruiting N/A Physiological Effects of HFNC During Exercise in Patients With Fibrosing Interstitial Lung Diseases November 22, 2022 November 23, 2024
NCT05375435 Recruiting Phase 4 Efficacy and Safety of Triple Therapy in Patients With Anti-MDA5 Antibody-positive Dermatomyositis January 1, 2022 December 31, 2024
NCT05382572 Recruiting Pulmonary Fibrosis Foundation Community Registry July 11, 2022 July 1, 2025
NCT05391100 Recruiting Screening of Patients With Rheumatoid Arthritis for Interstitial Lung Disease February 1, 2022 December 2026
NCT05392881 Recruiting Interstitial Lung Disease Research Unit Biobank August 9, 2021 March 1, 2032
NCT05417776 Recruiting Phase 2 Collagen-targeted PET Imaging for Early Interstitial Lung Disease September 28, 2022 April 1, 2024
NCT05445817 Recruiting Pulmonary Care and Research Collaborative Patient Registry July 2022 March 2024
NCT05482607 Recruiting Evaluation of HRCT Patterns in Systemic Sclerosis-associated Interstitial Lung Disease January 1, 2023 October 1, 2024
NCT05505409 Recruiting Phase 4 Efficacy and Safety of Pirfenidone in CTD-ILD June 22, 2022 December 1, 2025
NCT05514522 Recruiting The UK Interstitial Lung Disease Long-COVID19 Study (UKILD-Long COVID): Understanding the Burden of Interstitial Lung Disease in Long COVID. August 18, 2021 March 31, 2024
NCT05631132 Recruiting N/A May Noninvasive Mechanical Ventilation (NIV) and/or Continuous Positive Airway Pressure (CPAP) Increase the Bronchoalveolar Lavage (BAL) Salvage in Patients With Pulmonary Diseases? September 4, 2022 June 1, 2024
NCT05631756 Recruiting N/A Correlation Between PaO2/FiO2 and Lung Ultrasound Score in the Intensive Care Unit January 26, 2023 December 30, 2024
NCT05646407 Recruiting N/A Move With Air: Exercise Training Study April 1, 2023 March 30, 2025
NCT05649722 Recruiting Phase 2/Phase 3 An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) May 11, 2023 May 31, 2024
NCT05659550 Recruiting N/A Move With Air: Physiological Response Assessment April 1, 2023 December 30, 2024
NCT05662124 Recruiting N/A ILD: Health Outcomes in Remote Digital Monitoring Versus Usual Care March 7, 2023 April 2025
NCT05681962 Recruiting Practice of Oxygenation and Respiratory Support During Fiberoptic Bronchoscopy February 15, 2023 April 30, 2024
NCT05746039 Recruiting Phase 1/Phase 2 Feasibility of Semaglutide in Advanced Lung Disease January 29, 2024 June 28, 2024
NCT05776225 Recruiting Pulmonary Hypertension Screening in Patients With Interstitial Lung Disease for Earlier Detection August 11, 2023 February 1, 2025
NCT05810493 Recruiting A Cohort of Patients With Phenotyped Diffuse Interstitial Lung Disease With Longitudinal Follow-up January 1, 2022 December 31, 2025
NCT05824910 Recruiting N/A Effect of Pulmonary Telerehabilitation and Telemonitoring for Patients With Chronic Respiratory Diseases May 20, 2024 December 30, 2024
NCT05827302 Recruiting N/A Integrating ePReBMs From Phoenix in Respiratory Diseases October 11, 2023 April 2028
NCT05830318 Recruiting Usability and Acceptability Study of the P-STEP Mobile Application August 23, 2023 January 31, 2024
NCT05892614 Recruiting Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD) October 26, 2023 December 2024
NCT05894148 Recruiting Phase 1 Clinical Study of Multiple Dose Genakumab for Injection in Chinese Healthy Adults March 6, 2023 November 30, 2023
NCT05895409 Recruiting A Multicenter Prospective Study of Risk Factors in Progressive Pulmonary Fibrosis July 27, 2023 June 1, 2028
NCT05916404 Recruiting N/A Effects of Upper Extremity Aerobic Exercise Training in Patients With Interstitial Lung Disease July 3, 2023 June 1, 2025
NCT05943535 Recruiting Phase 3 Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF) October 30, 2023 November 2027
NCT05998512 Recruiting Integrating Molecular, Genomic, Morphology and Environmental Features to Improve Precision Diagnosis and Treatment in Interstitial Lung Diseases (PRECISION-ILD) July 10, 2023 December 31, 2025
NCT06016959 Recruiting N/A Specialist Dietetic Intervention in Malnourished Patients With Fibrotic ILD: a Randomised Controlled Pilot Trial June 20, 2023 March 1, 2024
NCT06027333 Recruiting Self-efficacy and Well-being of Patients With Fibrotic Interstitial Lung Disease November 8, 2023 August 30, 2024
NCT06038630 Recruiting Phase 2 129Xe MRI Cardiopulmonary January 12, 2024 June 30, 2028
NCT06046547 Recruiting N/A Integrating Palliative Care Education in Pulmonary Rehabilitation September 1, 2023 June 2026
NCT06066658 Recruiting N/A Anxiety Management in Breathlessness. October 2023 June 2024
NCT06068647 Recruiting N/A Ultrasound and Respiratory Physiological Signals in Lung Diseases March 22, 2023 March 31, 2025
NCT06087692 Recruiting N/A Efficacy of Video-Based Interactive Game Therapy in Interstitial Lung Patients January 1, 2023 March 1, 2024
NCT06090149 Recruiting N/A Telemedical Assistance in Automatic Titration of Oxygen for Intensive Care Patients March 1, 2023 November 30, 2023
NCT06129240 Recruiting An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH December 28, 2023 October 31, 2026
NCT06133998 Recruiting N/A Effects of Incentive Spirometry With and Without Aerobic Exercises in Interstitial Lung Disease September 20, 2023 December 10, 2023
NCT06141603 Recruiting Comparison of Upper and Lower Limb Maximal Exercise Capacities and Muscle Oxygenation in Patients With ILD November 25, 2023 December 30, 2024
NCT06143540 Recruiting Clinical Study of 18F-FAPI-RGD in Interstitial Lung Disease Associated With Connective Tissue Disease August 16, 2023 July 2024
NCT06247397 Recruiting N/A Effect of HIgh-flow Therapy in Long-term Oxygen Therapy June 10, 2024 December 2028
NCT06397677 Recruiting Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease January 22, 2024 January 2034
NCT04843345 Suspended Sjogren's Lung Study April 1, 2021 April 1, 2030
NCT02615938 Suspended Phase 2 Hydroxychloroquin (HCQ) in Pediatric Interstitial Lung Disease (ILD) April 2015 April 2025
NCT04036721 Suspended Phase 4 Coorticosteroid Regimen in Patients With Anti-PD-1/PD-L1 Induced Pneumonitis October 1, 2019 February 1, 2026
NCT01203943 Terminated Phase 2 A Study to Characterize the Safety, PK and Biological Activity of CC-930 in Idiopathic Pulmonary Fibrosis (IPF) January 1, 2011 August 24, 2012
NCT01424033 Terminated Phase 2/Phase 3 A Clinical Trial for CTD-ILD Treatment December 2011
NCT00744614 Terminated Use Of Capnography As Surrogate Measure Of PC02 In Medical Intensive Care Unit (ICU) Patients November 2007 October 2010
NCT01381666 Terminated Phase 2 Evaluation of the Diagnostic Utility of INS316 in Patients With Interstitial Lung Diseases (01-701) January 2003 April 2004
NCT02633293 Terminated Phase 2/Phase 3 An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE September 15, 2016 August 1, 2021
NCT04837131 Terminated Phase 2 A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients April 28, 2021 February 23, 2024
NCT05079126 Terminated Phase 2 Study of Trans Sodium Crocetinate in Patients With Interstitial Lung Disease December 2, 2021 May 27, 2022
NCT02958917 Terminated Phase 2 Study of Efficacy and Safety of Pirfenidone in Patients With Fibrotic Hypersensitivity Pneumonitis June 5, 2017 March 2, 2021
NCT02813447 Terminated N/A Safety of Anti-Depressant for Chronic Obstructive Pulmonary Disease (SAD-COPD) August 2016 February 20, 2019
NCT05267418 Terminated N/A Effects of Automated Oxygen Titration Alone or With High Flow Nasal Therapy on Dyspnea and Exercise Tolerance February 26, 2019 March 30, 2021
NCT01559129 Terminated Phase 2 Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effectiveness for Patients With Systemic Sclerosis With Interstitial Lung Disease August 9, 2012 November 3, 2016
NCT03958162 Unknown status N/A The Comparison of Uniportal and Tubeless Video Assisted Thoracic Surgery and Transbronchial Lung Cryobiopsy in the Diagnosis of Interstitial Lung Disease June 1, 2019 June 1, 2020
NCT03824834 Unknown status Phase 2 Morphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent Breathlessness August 6, 2019 November 2020
NCT03770663 Unknown status Phase 3 Cyclophosphamide and Azathioprine vs Tacrolimus in Antisynthetase Syndrome-related Interstitial Lung Disease February 5, 2021 January 2, 2024
NCT03726398 Unknown status Phase 2/Phase 3 CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PH September 1, 2018 December 1, 2020
NCT03670576 Unknown status It's Not JUST Idiopathic Pulmonary Fibrosis Study November 11, 2018 November 11, 2022
NCT03560154 Unknown status N/A Effects of Whole Body Vibration Training in Patients With Interstitial Lung Disease January 2017 September 2020
NCT03467880 Unknown status Multicenter Study of Impulse Oscillometry in Chinese September 2016 December 2018
NCT05106556 Unknown status N/A Effect of Respiratory Muscle Training in Interstitial Lung Patients December 9, 2019 January 31, 2022
NCT05129410 Unknown status Phase 4 Clinical Study of MMF in Treatment of IIM-ILD and Its Effect on Peripheral Blood Treg Cells December 1, 2020 November 30, 2023
NCT02827734 Unknown status Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD) October 2015 December 2020
NCT03440489 Unknown status N/A Assessment of Skeletal Muscle Dysfunction in Patient With Idiopathic Pulmonary Fibrosis July 2018 July 2020
NCT02826265 Unknown status Evaluation of Novel Lung Function Parameters and Quantitative Computed Tomography (qCT) in Patients With Pulmonary Disease January 2016 December 2020
NCT02150616 Unknown status Phase 4 Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Breathing and Sleep May 2014 December 2020
NCT02824757 Unknown status The Effects of Glucocorticoids on Glucose Metabolism in Patients With Interstitial Lung Disease March 2016 March 2017
NCT03400839 Unknown status Best Clinical Endpoints That Likely Induce Worse Prognosis in Interstitial Lung Diseases September 15, 2017 October 1, 2023
NCT05335278 Unknown status N/A Tolerability and Safety of Nintedanib in Myositis Associated Interstitial Lung Disease: a Pilot Study June 1, 2021 May 31, 2023
NCT00637065 Unknown status Phase 4 Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study April 2008 August 2010
NCT02821689 Unknown status Phase 4 Pirfenidone in Progressive Interstitial Lung Disease Associated With Clinically Amyopathic Dermatomyositis July 2016 June 2018
NCT00168285 Unknown status N/A Pulmonary Rehabilitation in Interstitial Lung Disease March 2005 May 2007
NCT01809574 Unknown status The Role of Rheumatological Evaluation in the Management of Patients With Interstitial Lung Disease May 2013 March 2016
NCT01711151 Unknown status Interstitial Lung Disease Questionnaire November 2012 November 2013
NCT03238989 Unknown status Interstitial Lung Disease Registry Construction January 5, 2014 December 31, 2023
NCT02136394 Unknown status The Role of Gastroesophageal Reflux in Scleroderma Pulmonary Fibrosis February 2014 April 2017
NCT03099525 Unknown status Treatment Outcome and Prognostic Factors for Rheumatoid Arthritis (RA) Patients With Interstitial Lung Disease (ILD) October 2016 March 2022
NCT03084419 Unknown status Phase 2 APRIL (AbatacePt in Rheumatoid Arthritis-ILD) June 26, 2018 March 1, 2020
NCT02885961 Unknown status N/A The Coagulation Cascade in Idiopathic Pulmonary Fibrosis August 2016
NCT02235779 Unknown status N/A Diagnostic Yield of Transbronchial Cryobiopsy in Diagnosis of Interstitial Lung Diseases August 2014 December 2021
NCT02579304 Unknown status Diagnostic Value of Transbronchial Lung Cryobiopsy January 2019 June 2023
NCT04624191 Unknown status N/A Clinical Impact of HOME Oxygen SATURation Measurement (SATURHOME) November 11, 2020 June 30, 2023
NCT02563730 Unknown status N/A Open Label Trial of Utility of Cryobiopsy in the Multidisciplinary Diagnosis of Idiopathic Interstitial Lung Disease November 2014
NCT04544722 Unknown status N/A Clinical Study of Jianfei Kangfu Cao in the Treatment of pSS-ILD October 1, 2020 June 1, 2023
NCT04805086 Unknown status Phase 1/Phase 2 The MONACO Cell Therapy Study: Monocytes as an Anti-fibrotic Treatment After COVID-19 March 8, 2021 March 5, 2023
NCT04428957 Unknown status N/A Telemonitoring of Treatment Effects in Connective Tissue Disease-associated Interstitial Lung Disease (TEL-CTD-ILD) February 11, 2020 April 2022
NCT04331548 Unknown status Endobronchial Ultrasound Transbronchial Needle Aspiration Of Enlarged Mediastinal In Interstitial Lung Disease May 30, 2020 January 30, 2024
NCT04193592 Unknown status Phase 2 Efficacy and Safety of Pirfenidone Treatment in HPS-ILD December 1, 2019 December 31, 2022
NCT04139356 Unknown status N/A The Effect of Spontaneous Respiration on Pulse-oximetry Measurements September 1, 2019 December 15, 2019
NCT04098094 Unknown status Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases September 19, 2019 October 30, 2022
NCT04089826 Unknown status Long Term Oxygen Therapy in Patients With Interstitial Lung Disease September 2019 October 2020
NCT02278107 Unknown status N/A Evaluation of a Lightweight Nasal Interface and Ventilator in Patients With Respiratory Disease July 2014 December 2016
NCT03977415 Unknown status Interstitial Lung Disease in Early Rheumatoid Arthritis March 27, 2018 August 1, 2021
NCT00625079 Withdrawn Phase 4 Pulmonary Hypertension Secondary to Idiopathic Pulmonary Fibrosis And Treatment With Sildenafil February 2007 December 2009
Disase is a (Disease Ontology)
DOID:850
Cross Reference ID (Disease Ontology)
GARD:13336
Cross Reference ID (Disease Ontology)
ICD10CM:J84.9
Cross Reference ID (Disease Ontology)
MESH:D017563
Cross Reference ID (Disease Ontology)
MIM:PS619611
Cross Reference ID (Disease Ontology)
NCI:C164315
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:64667001
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0206062
Exact Synonym (Disease Ontology)
ILD