ventricular septal defect

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Information
Disease name
ventricular septal defect
Disease ID
DOID:1657
Description
"A heart septal defect characterized by an opening in the interventricular septum, causing a shunt between ventricles." [url:http\://en.wikipedia.org/wiki/Ventricular_septal_defect, url:http\://www.merckmanuals.com/professional/pediatrics/congenital_cardiovascular_anomalies/ventricular_septal_defect_vsd.html]
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
GATA4 8 11,704,202 11,760,002 4
TBX20 7 35,202,430 35,254,100 4
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04667455 Active, not recruiting N/A Improving Care for Children With Congenital Heart Disease. February 17, 2020 October 2024
NCT04017975 Active, not recruiting Phase 2 Optical Tissue Identification for Myocardial Architecture December 20, 2019 September 2023
NCT01313832 Completed N/A The Effect of Remote Ischemic Preconditioning on the Ischemic Reperfusion Injury in Infants With Ventricular Septal Defect and Pulmonary Hypertension December 2010 April 2011
NCT01915277 Completed Phase 1 A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics April 2, 2014 October 17, 2017
NCT02138435 Completed Longterm Outcome After Ventricular Septal Defect Closure March 2014 August 2016
NCT02914652 Completed Phase 4 The Cardiopulmonary Effect of Inhaled Beta-2-agonists on Adult Patients Born With Ventricular Septum Defects. October 15, 2016 January 1, 2018
NCT03684161 Completed Cardiopulmonary Function in Adults Born With a Ventricular Septal Defect September 24, 2018 September 1, 2019
NCT00556361 Completed Phase 2 Use of Ketamine Prior to Cardiopulmonary Bypass in Children July 2004 November 2007
NCT01120964 Completed Phase 1/Phase 2 Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised Protocol September 2010 April 2012
NCT04417712 Completed Lifetech KONAR MFO Post-Market Clinical Follow-Up Study December 4, 2019 June 30, 2023
NCT04859036 Completed The Effect of Transcatheter Ventricular Septal Defect Closure on Heart Rate Variability Parameters April 1, 2016 April 1, 2017
NCT05200910 Completed The Effect of Transcatheter VSD Closure on Children's Appetite, Hormones and Growth July 16, 2018 January 1, 2020
NCT06214182 Enrolling by invitation Immune Heterogeneity Before and After Cardiopulmonary Bypass in Children January 1, 2024 December 31, 2024
NCT06298344 Recruiting Early Phase 1 The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease May 1, 2024 January 1, 2025
NCT05253209 Recruiting Phase 3 A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects June 29, 2022 February 10, 2024
NCT05688670 Recruiting Phase 4 Regional Anesthesia Following Pediatric Cardiac Surgery March 29, 2023 June 1, 2025
NCT05939713 Recruiting Cera™ VSD Occluder Post Market Clinical Follow-up October 13, 2023 December 2024
NCT03127748 Unknown status Cardiac Function After Transcatheter VSD Closure July 1, 2015 June 30, 2017
NCT03941691 Unknown status N/A A Trial to Evaluate the Safety and Efficacy of a Fully Degradable Ventricular Septal Defect (VSD) Closure April 11, 2019 April 20, 2021
Disase is a (Disease Ontology)
DOID:1681
Cross Reference ID (Disease Ontology)
GARD:7853
Cross Reference ID (Disease Ontology)
ICD10CM:Q21.0
Cross Reference ID (Disease Ontology)
ICD9CM:745.4
Cross Reference ID (Disease Ontology)
MESH:D006345
Cross Reference ID (Disease Ontology)
MIM:614429
Cross Reference ID (Disease Ontology)
MIM:614431
Cross Reference ID (Disease Ontology)
MIM:614432
Cross Reference ID (Disease Ontology)
NCI:C84506
Cross Reference ID (Disease Ontology)
ORDO:1480
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:156914003
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0018818
Exact Synonym (Disease Ontology)
Interventricular septal defect
Exact Synonym (Disease Ontology)
Ventricular septal abnormality
HPO alt_id (Human Phenotype Ontology)
HP:0001652
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0001629
OMIM Phenotype Series Number (OMIM)
PS614429
ICD10 preferred id (Insert disease from ICD10)
D0013652
ICD10 class code (Insert disease from ICD10)
Q21.0