patent ductus arteriosus
Information
- Disease name
- patent ductus arteriosus
- Disease ID
- DOID:13832
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03782610 | Active, not recruiting | Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes | April 1, 2019 | June 2026 | |
| NCT04667455 | Active, not recruiting | N/A | Improving Care for Children With Congenital Heart Disease. | February 17, 2020 | October 2024 |
| NCT02739087 | Active, not recruiting | N/A | Radiation-Free Heart Catheterization Using MRI | March 2015 | December 2024 |
| NCT00440804 | Completed | Phase 3 | Safety and Efficacy Study of Ibuprofen l-Lysine Solution in Premature Infants for Treatment of PDA | December 2002 | August 2005 |
| NCT00485160 | Completed | Phase 3 | Ibuprofen vs. Continuous Indomethacin in the Treatment of PDA | February 2002 | September 2006 |
| NCT00500305 | Completed | N/A | The Use of B-type Natriuretic Peptide (BNP) to Predict Closure of a Patent Ductus Arteriosus (PDA) in Premature Infants | April 2004 | March 2007 |
| NCT00642330 | Completed | Phase 4 | Comparative Study of Efficacy and Safety of Oral Ibuprofen and Intravenous Ibuprofen in Closure of Patent Ductus Arteriosus in Very Low Birth Weight Infants | January 2007 | December 2007 |
| NCT00713700 | Completed | N/A | AMPLATZER Duct Occluder II Clinical Study | August 2008 | October 5, 2016 |
| NCT00728117 | Completed | N/A | Feeding During Ibuprofen or Indomethacin Treatment of Preterm Infants | July 2008 | September 2012 |
| NCT00162903 | Completed | Nitric Oxide, Endothelin-1, and the Patency of Ductus Arteriosus in Preterm Infants | January 2002 | December 2002 | |
| NCT00187447 | Completed | Phase 2 | Comparison of 2 Different Indomethacin Dosing Protocols to Treat Infants Delivered at <28 Weeks Gestation With a Persistent Patent Ductus Arteriosus | August 2003 | July 2006 |
| NCT00217191 | Completed | Phase 4 | Ibuprofen and Renal Function in Premature Infants | September 2004 | September 2006 |
| NCT00795990 | Completed | Timing for the Medical Treatment of Patent Ductus Arteriosus in Preterm Infants | November 2008 | November 2014 | |
| NCT01261117 | Completed | N/A | Efficacy and Safety of Oral Versus Intravenous Ibuprofen for PDA Treatment in ELBW Infants | January 2009 | June 2011 |
| NCT01428180 | Completed | Influence of Treatment for Patent Ductus Arteriosus on Cerebral Oxygenation in Preterm Infants | April 2011 | March 2016 | |
| NCT01479218 | Completed | N/A | Safety and Effectiveness Study With a New PDA Occluder for Closure of Patent Ductus Arteriosus | November 2011 | May 2014 |
| NCT01497054 | Completed | Do Elevated BNP Levels Predict Hemodynamically Significant PDAs | December 2011 | April 2013 | |
| NCT01511887 | Completed | N/A | Safety and Efficacy of Ibuprofen in Term Newborns With Patent Ductus Arteriosus (PDA) | January 2011 | January 2012 |
| NCT01536158 | Completed | Phase 4 | Oral Paracetamol Versus Oral Ibuprofen in Management of Patent Ductus Arteriosus in Preterm Infants: A Randomised Controlled Trial | February 2012 | December 2012 |
| NCT01593163 | Completed | Phase 3 | Echocardiographically Guided Versus Standard Ibuprofen Treatment for Patent Ductus Arteriosus | May 2009 | March 2010 |
| NCT01630278 | Completed | Phase 3 | Early Ibuprofen Treatment of Patent Ductus Arteriosus (PDA) in Premature Infants (TRIOCAPI) | March 2012 | June 2019 |
| NCT01758913 | Completed | N/A | Closure of Patent Ductus Arteriosus With Indomethacin or Ibuprofen in Extreme Low Birth Weight Infants | February 2007 | February 2012 |
| NCT01790750 | Completed | N/A | Pocket Echocardiography System (PES) for Detection of PDA in Neonates | February 2013 | May 2013 |
| NCT01929733 | Completed | Long Term Results of 450 Percutaneous Closures of PDA in a Single Center | January 1998 | August 2013 | |
| NCT01958320 | Completed | Phase 2 | Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus | December 2013 | June 2017 |
| NCT02621528 | Completed | N/A | Lifetech CeraFlex™ Post-Market Surveillance Study | October 2015 | February 2020 |
| NCT02750228 | Completed | PDA Post NICU Discharge | May 2016 | June 30, 2020 | |
| NCT02884219 | Completed | N/A | Early Treatment Versus Expectative Management of PDA in Preterm Infants | December 23, 2016 | March 15, 2022 |
| NCT03008876 | Completed | N/A | IV Acetaminophen and Patent Ductus Arteriosus | January 1, 2017 | June 30, 2019 |
| NCT03022253 | Completed | Phase 3 | Platelet Transfusion for Treatment of Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates | March 2016 | March 20, 2017 |
| NCT03055858 | Completed | N/A | AMPLATZER Duct Occluder II Additional Sizes | June 5, 2017 | April 5, 2022 |
| NCT03103022 | Completed | Phase 1 | Combination of Acetaminophen and Ibuprofen in the Management of Patent Ductus Arteriosus | June 12, 2017 | April 30, 2019 |
| NCT03277768 | Completed | Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus. | May 1, 2015 | August 23, 2018 | |
| NCT03289390 | Completed | Treatment of a PDA With Acetaminophen in Preterm Neonates: Exploring Various Indications | August 1, 2017 | June 30, 2019 | |
| NCT03551600 | Completed | Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus | October 2015 | June 30, 2022 | |
| NCT03723889 | Completed | Patent Ductus Arteriosus and Splanchnic Oxygenation at First Feed | November 1, 2013 | October 31, 2016 | |
| NCT03860428 | Completed | N/A | Early Treatment Versus Expectant Management of PDA in Preterm Infants | February 15, 2019 | July 20, 2021 |
| NCT04077333 | Completed | N/A | MISA to NRDS：a Multicenter Study in China | July 1, 2017 | March 30, 2019 |
| NCT04123691 | Completed | Cardio-respiratory Events in Preterm Infants During Transition | February 21, 2018 | September 2, 2019 | |
| NCT04126512 | Completed | Timing of Surgical PDA Ligation and Neonatal Outcomes | September 25, 2019 | December 31, 2019 | |
| NCT04184245 | Completed | Hemodynamic Responses to Cardio-respiratory Events in Preterm Infants | February 22, 2018 | January 3, 2020 | |
| NCT06152796 | Not yet recruiting | Phase 2 | Comparision Between Paracetamol and Ibuprofen in Closure of Patent Ductus Arteriosus | December 1, 2023 | January 1, 2026 |
| NCT06045130 | Not yet recruiting | PUFAs in Preterm Infants | September 21, 2023 | August 31, 2026 | |
| NCT06256211 | Not yet recruiting | Phase 1/Phase 2 | Assessment of Therapeutic Effect of Rectal Vs. Intravenous Paracetamol in The Treatment of Patent Ductus Arteriosus (PDA) in Neonates | March 1, 2024 | December 30, 2024 |
| NCT03648437 | Recruiting | Phase 1 | Paracetamol And Ibuprofen/Indomethacin in Closing Patent Ductus Arteriosus | September 3, 2018 | March 1, 2024 |
| NCT04371081 | Recruiting | Amplatzer Piccolo Occluder Japan Post-marketing Database Surveillance | April 1, 2020 | May 31, 2025 | |
| NCT05264753 | Recruiting | PMCF Study to Evaluate Efficacy, Safety of the Occlutech PDA Occluder in Patients With Patent Ductus Arteriosus Defects | December 20, 2021 | November 25, 2026 | |
| NCT03456336 | Recruiting | Phase 3 | Management of the PDA Trial | December 3, 2018 | March 2029 |
| NCT05639309 | Recruiting | Liver Regional Oxygen Saturation in Preterm Patent Ductus Arteriosus | January 13, 2023 | October 31, 2025 | |
| NCT04986839 | Recruiting | Phase 2/Phase 3 | PAIR (Paracetamol and Ibuprofen Research) Pilot Trial | September 3, 2021 | January 1, 2024 |
| NCT04984057 | Recruiting | N/A | Optimal Dose of Surfactant for Preterm Infants With Respiratory Distress Syndrome | August 1, 2021 | December 31, 2024 |
| NCT06298344 | Recruiting | Early Phase 1 | The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease | May 1, 2024 | January 1, 2025 |
| NCT04347720 | Recruiting | Canadian National PDA Treatment Study | January 1, 2020 | September 1, 2023 | |
| NCT03701074 | Terminated | Phase 2 | Randomized Controlled Trial to Evaluate the Safety and Efficacy of Acetaminophen in Preterm Infants Used in Combination With Ibuprofen for Closure of the Ductus Arteriosus | December 15, 2018 | December 2, 2020 |
| NCT03026192 | Terminated | Near Infrared Spectroscopy to Determine Patent Ductus Arteriosus Closure | December 2016 | June 30, 2018 | |
| NCT03982342 | Terminated | N/A | Preliminary Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low-weight Infants | October 10, 2020 | August 31, 2021 |
| NCT03537144 | Terminated | Phase 3 | Acetaminophen vs Indomethacin in Treating hsPDA | June 2016 | September 2018 |
| NCT00767039 | Terminated | Phase 4 | Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants | January 2005 | January 2009 |
| NCT00802685 | Terminated | N/A | Timing of PDA Closure and Respiratory Outcome in Premature Infants | November 2007 | February 2011 |
| NCT00833365 | Terminated | N/A | Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure | January 2009 | November 2011 |
| NCT00961753 | Terminated | Phase 4 | Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates | August 2009 | October 2010 |
| NCT00750581 | Terminated | Phase 2/Phase 3 | An Escalating Dose Indomethacin for the Treatment of Persistent Patent Ductus Arteriosus (PDA) In Preterm Infants | August 2008 | January 2013 |
| NCT02894970 | Unknown status | A New Device for Measuring of Lung Photoplethysmography and Pulmonic Arterial Saturation | October 2016 | July 2017 | |
| NCT04397913 | Unknown status | Population Pharmacokinetics and Dosage Individualization of Paracetamol and Ibuprofen in Children With PDA | May 25, 2020 | May 6, 2023 | |
| NCT04415554 | Unknown status | Aminoglycosides and Duct | July 2021 | December 2022 | |
| NCT04672629 | Unknown status | Clinical Profile of Neonates Having Patent Ductus Arteriosus | April 1, 2021 | February 2022 | |
| NCT03265782 | Unknown status | Phase 4 | Paracetamol Versus Ibuprofen for PDA Closure | June 2015 | January 2018 |
| NCT04964531 | Unknown status | Effect of PDA Closure on the Left Ventricular Remodeling | July 2021 | February 2023 | |
| NCT01291654 | Unknown status | Phase 2 | Paracetamol and Patent Ductus Arteriosus (PDA) | April 2012 | |
| NCT00616382 | Unknown status | Phase 2 | Treating the Resistant Patent Ductus Arteriosus (PDA) | March 2008 | |
| NCT01544972 | Unknown status | Phase 4 | Serum Level Measurement of Oral Paracetamol and Oral Ibuprofen for Patent Ductus Arteriosus Treatment in Preterm Infants | February 2012 | December 2012 |
| NCT02380040 | Unknown status | Plethismographic Perfusion Index in Neonates | March 2015 | March 2017 | |
| NCT04291222 | Unknown status | N/A | Feasibility, Efficacy and Safety of IBS ® for Implantaiton in the PDA in Duct-dependent Cyanotic CHD | December 11, 2018 | August 2021 |
| NCT02819414 | Unknown status | Phase 2 | Paracetamol Treatment of the Borderline Significant PDA | June 2016 | January 2019 |
| NCT02910609 | Unknown status | International Experience in Timing And Choices for Ductal Closure in Patent Ductus Arteriosus:INTERPDA Trial | January 2017 | March 2018 | |
| NCT04270240 | Unknown status | A NEW SCORING SYSTEM FOR PREDICTION OF PDA | January 15, 2019 | February 15, 2021 | |
| NCT02220270 | Unknown status | Hyperion™ International Registry Trial | May 2015 | August 2017 | |
| NCT04026464 | Withdrawn | Phase 2 | Addition of Acetaminophen in Standard PDA Management | April 2021 | May 12, 2021 |
| NCT00554307 | Withdrawn | Brain, Gut and Kidney Blood Flow During Medical Closure of PDA | November 2007 | December 2009 | |
| NCT01070745 | Withdrawn | Phase 2 | Second Course of Therapy for Resistant Patent Ductus Arteriosus (PDA) | June 2010 | |
| NCT01028183 | Withdrawn | Impact of Maternal-infant Therapeutics on Safety, Mortality, and Disability | August 2010 | July 2013 |
- Disase is a (Disease Ontology)
- DOID:1682
- Cross Reference ID (Disease Ontology)
- GARD:7342
- Cross Reference ID (Disease Ontology)
- ICD10CM:Q25.0
- Cross Reference ID (Disease Ontology)
- ICD9CM:747.0
- Cross Reference ID (Disease Ontology)
- MESH:D004374
- Cross Reference ID (Disease Ontology)
- MIM:607411
- Cross Reference ID (Disease Ontology)
- NCI:C84492
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:156928009
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0013274
- Exact Synonym (Disease Ontology)
- Patent ductus Botalli
- Disase Synonym (Disease Ontology)
- ductus arteriosus, Patent
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0001643
- OMIM Phenotype Series Number (OMIM)
- PS607411
- ICD10 preferred id (Insert disease from ICD10)
- D0013688
- ICD10 class code (Insert disease from ICD10)
- Q25.0