Annotation Detail
Information
- Associated Genes
- MYC
- Associated Variants
- MYC EXPRESSION
- Source Database
- MMMP
- Description
- In vitro data suggest that one of the major functions of c-MYC overexpression in melanoma progression is to continuously suppress BRAF(V600E)- or NRAS(Q61R)-dependent senescence programs. Accordingly, MYC knockdown leads to cell cycle arrest or apoptosis
- MMMP State
- expressed
- MMMP Molecule
- MYC
- MMMP Molecule Alias
- c-Myc
- MMMP Relationship
- sensitivity to
- MMMP Drug
- MYC siRNA
- MMMP Model
- 3
- MMMP Reference
- Zhuang D, Oncogene 2008, 27:6623-34
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| MYC siRNA | Sensitivity | true |