Annotation Detail
Information
- Associated Genes
- FGF2
- Associated Variants
- FGF2 EXPRESSION
- Source Database
- MMMP
- Description
- bFGF overexpression can result in resistance against temozolomide mediated by demethylation of the O6-methylguanine-DNA-methyltransferase promoter
- MMMP State
- expressed
- MMMP Molecule
- FGF-2
- MMMP Molecule Alias
- Fibroblast growth factor 2 (bFGF)
- MMMP Relationship
- no relationship with
- MMMP Drug
- Doxorubicin
- MMMP Drug Alias
- Adriamycin (R)
- MMMP Model
- 3
- MMMP Reference
- Fontijn D, Mol Cancer Ther 2007, 6:2807-15
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Doxorubicin | Resitance or Non-Reponse | true |