Annotation Detail
Information
- Associated Genes
- CFLAR
- Associated Variants
- CFLAR UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Cisplatin inhibits c-FLIP protein expression and phosphorylation to restore TRAIL-induced caspase-8-initiated apoptosis in melanoma cells, thus providing a new combined therapeutic strategy for melanomas
- MMMP State
- inhibited by
- MMMP Molecule
- FLIP
- MMMP Molecule Alias
- c-FLIP
- MMMP Modifier
- Cisplatin
- MMMP Modifier Alias
- CDDP
- MMMP Relationship
- sensitivity to
- MMMP Drug
- TRAIL
- MMMP Model
- 3
- MMMP Reference
- Song JH, Clin Cancer Res 2003, 9:4255-66
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| TRAIL | Sensitivity | true |