Annotation Detail
Information
- Associated Genes
- MYC
- Associated Variants
- MYC UNDEREXPRESSION
- Source Database
- MMMP
- Description
- MYC downregulation sensitizes melanoma to radiation by inhibiting MLH1 and MSH2 expression. Sensitization is p53 independent
- MMMP State
- downregulated by
- MMMP Molecule
- MYC
- MMMP Molecule Alias
- c-Myc
- MMMP Modifier
- MYC antisense oligo
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Radiotherapy
- MMMP Model
- 3
- MMMP Reference
- Bucci B, Clin Cancer Res 2005, 11:2756-67
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Radiotherapy | Sensitivity | true |