Annotation Detail

Information
Associated Genes
ABCC1
Associated Variants
ABCC1 EXPRESSION
Source Database
MMMP
Description
The sensitivity of melanoma cell lines to daunomycin (DM) and doxorubicin (DOX), but not to vinblastine (VBL), etoposide (VP-16) and cisplatin (CDDP), analysed by an MTT-based survival assay, were inversely correlated with MRP-gene expression
MMMP State
expressed
MMMP Molecule
ABCC1
MMMP Molecule Alias
MRP1
MMMP Relationship
resistance to
MMMP Drug
Doxorubicin
MMMP Drug Alias
Adriamycin (R)
MMMP Model
3
MMMP Reference
Berger W, Int J Cancer 1997, 71:108-15
MMMP DNA/mRNA/Protein
mRNA
Drugs
Drug NameSensitivitySupported
DoxorubicinResitance or Non-Reponsetrue