Annotation Detail
Information
- Associated Genes
- BRAF
- Associated Variants
- BRAF V600E
- Source Database
- MMMP
- Description
- CI-1040 is a MEK inhibitor. Mutation of BRAF is associated with enhanced and selective sensitivity to MEK inhibition when compared to either BRAF wild-type cells or cells harboring a RAS mutation
- MMMP State
- mut V600E
- MMMP Molecule
- BRAF
- MMMP Molecule Alias
- B-Raf
- MMMP Relationship
- sensitivity to
- MMMP Drug
- CI-1040
- MMMP Drug Alias
- PD184352
- MMMP Model
- 4
- MMMP Reference
- Solit DB, Nature 2006, 439:358-62
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| CI-1040 | Sensitivity | true |