Annotation Detail
Information
- Associated Genes
- BIRC5
- Associated Variants
- BIRC5 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis
- MMMP Molecule Alias
- BIRC5
- MMMP Modifier
- Survivin siRNA
- MMMP State
- downregulated by
- MMMP Molecule
- Survivin
- MMMP Relationship
- sensitivity to
- MMMP Drug
- TRAIL
- MMMP Model
- 3
- MMMP Reference
- Chawla-Sarkar M, Cell Death Differ 2004, 11:915-23
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| TRAIL | Sensitivity | true |