Annotation Detail
Information
- Associated Genes
- CSPG4
- Associated Variants
- CSPG4 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- HMW-MAA inhibition seems to act through inhibition of alpha3beta1 integrin/PI3K signaling
- MMMP State
- downregulated by
- MMMP Molecule
- HMW-MAA
- MMMP Molecule Alias
- gp240, CSPG4, NG2, High molecular weight melanoma associated antigen
- MMMP Modifier
- HMW-MAA siRNA
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Doxorubicin
- MMMP Drug Alias
- Adriamycin (R)
- MMMP Model
- 3
- MMMP Reference
- Chekenya M, Oncogene 2008, 27:5182-94
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Doxorubicin | Sensitivity | true |