Annotation Detail
Information
- Associated Genes
- IGF1
- Associated Variants
- IGF1 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- IGF1 acts through upregulation of Bcl-2, Bcl-xL and survivin
- MMMP State
- downregulated by
- MMMP Molecule
- IGF1
- MMMP Molecule Alias
- Insulin-like growth factor 1
- MMMP Modifier
- IGF1 siRNA
- MMMP Relationship
- sensitivity to
- MMMP Drug
- TRAIL
- MMMP Model
- 3
- MMMP Reference
- Hilmi C, J Invest Dermatol 2008, 128:1499-505
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| TRAIL | Sensitivity | true |