Annotation Detail
Information
- Associated Genes
- KIT
- Associated Variants
- KIT D820Y
- Source Database
- MMMP
- Description
- Acral lentiginous melanoma. While imatinib did not affect the proliferation of SM3 cells, sunitinib showed marked growth inhibition against this cell harboring the D820Y mutation
- MMMP State
- mut D820Y
- MMMP Molecule
- KIT
- MMMP Molecule Alias
- c-KIT
- MMMP Relationship
- no relationship with
- MMMP Drug
- Imatinib
- MMMP Drug Alias
- Gleevec (R)
- MMMP Model
- 3
- MMMP Reference
- Ashida A, Int J Cancer 2009, 124:862-8
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Imatinib | Resitance or Non-Reponse | true |