Annotation Detail
Information
- Associated Genes
- BCL2
- Associated Variants
- BCL2 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Mebendazole (an anthelmintic drug) seems to act through Bcl-2 phosphorylation, which prevents Bcl-2 interaction with pro-apoptotic protein Bax
- MMMP State
- downregulated by
- MMMP Molecule
- Bcl-2
- MMMP Modifier
- Bcl-2 siRNA
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Mebendazole
- MMMP Model
- 3
- MMMP Reference
- Doudican N, Mol Cancer Res 2008, 6:1308-15
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Mebendazole | Sensitivity | true |