Annotation Detail
Information
- Associated Genes
- BMF
- Associated Variants
- BMF UNDEREXPRESSION
- Source Database
- MMMP
- Description
- CI-1040: MEK inhibitor. BMF expression is necessary for MEK inhibition to be therapeutically effective
- MMMP State
- downregulated by
- MMMP Molecule
- BMF
- MMMP Modifier
- BMF siRNA
- MMMP Relationship
- resistance to
- MMMP Drug
- CI-1040
- MMMP Drug Alias
- PD184352
- MMMP Model
- 3
- MMMP Reference
- VanBrocklin MW, Cancer Res 2009, 69:1985-94
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| CI-1040 | Resitance or Non-Reponse | true |