Annotation Detail
Information
- Associated Genes
- BMF
- Associated Variants
- BMF A69P
- Source Database
- MMMP
- Description
- This mutation reduces BMF interaction with DLC2, which sequesters BMF to the cytoskeleton and in turn inhibits apoptosis
- MMMP State
- mut A69P
- MMMP Molecule
- BMF
- MMMP Relationship
- sensitivity to
- MMMP Drug
- CI-1040
- MMMP Drug Alias
- PD184352
- MMMP Model
- 3
- MMMP Reference
- VanBrocklin MW, Cancer Res 2009, 69:1985-94
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| CI-1040 | Sensitivity | true |